2024
The complexity of treatment-resistant depression: A data-driven approach
Rost F, Booker T, Gonsard A, de Felice G, Asseburg L, Malda-Castillo J, Koutoufa I, Ridsdale H, Johnson R, Taylor D, Fonagy P. The complexity of treatment-resistant depression: A data-driven approach. Journal Of Affective Disorders 2024, 358: 292-301. PMID: 38697222, DOI: 10.1016/j.jad.2024.04.093.Peer-Reviewed Original ResearchTreatment-resistant depressionPersonality disorderSuicide attemptsChronic course of depressionCourse of depressionCo-occurring problemsDuration of illnessPhysical health problemsAdverse childhood experiencesPhysical health conditionsDepressive illnessPsychiatric diagnosisSuicidal ideationOccupational functioningPersistent depressionSeverely impaired quality of lifeQuality of lifeChildhood experiencesPragmatic randomized controlled trialDepressionChronic courseSuicideRecall biasClinical descriptionImpaired quality of life
2023
The relationship between mood disorders, personality disorder and suicidality in adolescence: does general personality disturbance play a significant role in predicting suicidal behavior?
Williams R, Chiesa M, Moselli M, Frattini C, Casini M, Fonagy P. The relationship between mood disorders, personality disorder and suicidality in adolescence: does general personality disturbance play a significant role in predicting suicidal behavior? Borderline Personality Disorder And Emotion Dysregulation 2023, 10: 32. PMID: 37907967, PMCID: PMC10619325, DOI: 10.1186/s40479-023-00238-9.Peer-Reviewed Original ResearchSignificant risk factorsSix-month followRisk factorsMajor depressionSuicide attemptsSuicidal riskPersonality disorderSuicidal behaviorClinical monitoringSuicidal ideationMixed-effects Poisson regressionAssessment of PDsPersonality disturbancePersonality pathologyDSM-IV personality disordersCumulative risk factorsLogistic regression modelsSpecific personality disordersIndividual personality disordersMood disordersOutpatient unitKiddie-SADSLevels of severitySCID-IIEarly identification