2010
The Relationship Between Mood, Stress, and Tobacco Smoking
Walderhaug E, Cosgrove K, Bhagwagar Z, Neumeister A. The Relationship Between Mood, Stress, and Tobacco Smoking. 2010, 147-161. DOI: 10.1007/978-1-4419-6373-4_10.Peer-Reviewed Original ResearchTobacco smokingPrimary addictive substancePositron emission tomographySingle photon emissionNicotine sharesTobacco smokeNicotine dependenceNicotine addictionHealthy peopleAbuse potentialEmission tomographyBehavioral effectsAnxiety disordersAddictive substancesSmokingHigh rateNicotineMolecular imagingMoodTomographyPsychostimulantsIndividuals
2004
Effects of beta-adrenoceptor blockade on components of human decision-making
Rogers R, Lancaster M, Wakeley J, Bhagwagar Z. Effects of beta-adrenoceptor blockade on components of human decision-making. Psychopharmacology 2004, 172: 157-164. PMID: 14716472, DOI: 10.1007/s00213-003-1641-5.Peer-Reviewed Original ResearchConceptsProbabilistic rewardsCortico-limbic systemsBrain imaging studiesSeries of choicesOrbitofrontal cortexEmotional aspectsSubjective stateSubjects designPunishment signalsCingulate cortexNegative ratingsProbability of losingNeurological patientsSubjective changesHealthy volunteersMoodRewardBeta-adrenoceptor blockadeCatecholamine systemsBeta-adrenoceptor blockersVisual analog scaleImaging studiesSlower heart rateCortexConclusionsThese results
2003
Acute SSRI Administration Affects the Processing of Social Cues in Healthy Volunteers
Harmer C, Bhagwagar Z, Perrett D, Völlm B, Cowen P, Goodwin G. Acute SSRI Administration Affects the Processing of Social Cues in Healthy Volunteers. Neuropsychopharmacology 2003, 28: 148-152. PMID: 12496951, DOI: 10.1038/sj.npp.1300004.Peer-Reviewed Original ResearchConceptsEmotional processingFacial expressionsFacial expression recognition taskExpression recognition taskAcute SSRI administrationBasic emotionsSocial cuesEmotional intensityNeural processesSocial informationRecognition taskEarly acute effectsReduced response timeEmotional standardsSubjective experienceSocial behaviorTesting sessionsSSRI administrationAcute administrationMoodSelective serotonin reuptake inhibitorsProcessingSerotonin reuptake inhibitorsRole of serotoninHealthy female volunteers
2002
Tryptophan Depletion Alters the Decision-Making of Healthy Volunteers through Altered Processing of Reward Cues
Rogers R, Tunbridge E, Bhagwagar Z, Drevets W, Sahakian B, Carter C. Tryptophan Depletion Alters the Decision-Making of Healthy Volunteers through Altered Processing of Reward Cues. Neuropsychopharmacology 2002, 28: 153-162. PMID: 12496952, DOI: 10.1038/sj.npp.1300001.Peer-Reviewed Original ResearchConceptsAmino acid drinkReward cuesOrbitofrontal cortexNegative outcomesReduced discriminationAltered processingTryptophan depletionHuman choiceCuesMonoamine neurotransmitter systemsAltered discriminationNeurotransmitter systemsBiasesDiscriminationCortexGamblesProcessingPsychiatric illnessCognitionHealthy volunteersAnhedoniaMoodFunctioningPresent studyLittle evidence
2000
Modelling a loss event: effect of imagined bereavement on the hypothalamic–pituitary–adrenal axis
McCLEERY J, BHAGWAGAR Z, SMITH K, GOODWIN G, COWEN P. Modelling a loss event: effect of imagined bereavement on the hypothalamic–pituitary–adrenal axis. Psychological Medicine 2000, 30: 219-223. PMID: 10722192, DOI: 10.1017/s0033291799001361.Peer-Reviewed Original ResearchConceptsNegative mood induction procedureNegative mood inductionMood induction procedureMood inductionRelevant psychosocial stressorsIndividual differencesCortisol responseSalivary cortisol responseTransient moodPsychological stateInduction procedureAcute cortisol responsePsychosocial stressorsMood disorders researchDisorder researchCortisol outputStressorsBereavementNeuroendocrine responsesMoodAdrenal axisDepressive illnessHealthy volunteersMusicImportant mediator