2022
Skin dose distributions between Stanford and rotational techniques in total skin electron therapy (TSET)
Ding G, Chen Z, Zhong W, Zhu T. Skin dose distributions between Stanford and rotational techniques in total skin electron therapy (TSET). Medical Physics 2022, 49: 6646-6653. PMID: 35972019, DOI: 10.1002/mp.15907.Peer-Reviewed Original ResearchMeSH KeywordsElectronsHumansMonte Carlo MethodRadiotherapy DosageRadiotherapy Planning, Computer-AssistedSkinSkin NeoplasmsConceptsTotal skin electron therapyDose coverageStanford techniqueAdvanced-stage cutaneous T-cell lymphomaCutaneous T-cell lymphomaSkin dose distributionRotational techniqueT-cell lymphomaPatient's postureSimilar dose coverageDose distributionExtended treatment distancesElectron therapyMean doseEffective treatmentSame patientSmall dose differencesClinical settingPatient treatmentSkin dosesRealistic clinical settingsSkin doseDoseDifferent posturesDistribution of dose
2020
A general-purpose Monte Carlo particle transport code based on inverse transform sampling for radiotherapy dose calculation
Liang Y, Muhammad W, Hart GR, Nartowt BJ, Chen ZJ, Yu JB, Roberts KB, Duncan JS, Deng J. A general-purpose Monte Carlo particle transport code based on inverse transform sampling for radiotherapy dose calculation. Scientific Reports 2020, 10: 9808. PMID: 32555530, PMCID: PMC7300009, DOI: 10.1038/s41598-020-66844-7.Peer-Reviewed Original ResearchConceptsPhoton transportBoundary crossing algorithmMonte Carlo particle transport codeMonte Carlo methodTransport simulationsAcceptance-rejection samplingRadiotherapy dose calculationsPhoto-electric effectParticle transport codeEGSnrc simulationsCarlo methodBremsstrahlung eventsInelastic scatteringPair productionRayleigh scatteringThread divergenceMC simulationsTransport codeMC codeHistory schemeParticle transportCrossing algorithmInverseElectron transportSimulation accuracy
2019
Deployment and performance of model-based dose calculation algorithm in 192Ir shielded cylinder brachytherapy
Tien CJ, Chen ZJ. Deployment and performance of model-based dose calculation algorithm in 192Ir shielded cylinder brachytherapy. Brachytherapy 2019, 18: 883-889. PMID: 31444132, DOI: 10.1016/j.brachy.2019.07.006.Peer-Reviewed Original Research
2018
Monte Carlo dosimetry modeling of focused kV x‐ray radiotherapy of eye diseases with potential nanoparticle dose enhancement
Yan H, Ma X, Sun W, Mendez S, Stryker S, Starr‐Baier S, Delliturri G, Zhu D, Nath R, Chen Z, Roberts K, MacDonald CA, Liu W. Monte Carlo dosimetry modeling of focused kV x‐ray radiotherapy of eye diseases with potential nanoparticle dose enhancement. Medical Physics 2018, 45: 4720-4733. PMID: 30133705, DOI: 10.1002/mp.13144.Peer-Reviewed Original ResearchConceptsX-ray beamMC simulation programEye plaque treatmentCentral axis depth doseMC simulationsDose distributionBeam focusingEye Physics plaquesPhantom irradiationDose enhancementEnergy spectrumDepth doseLens modelingDosimetry modelingPhotoelectric absorptionKV rangeKV X-ray beamsBeamEBT3 filmSimulation programEnergy regimeModelingX-ray techniquesHalf maximumMore flexibility
2015
Concomitant Imaging Dose and Cancer Risk in Image Guided Thoracic Radiation Therapy
Zhang Y, Wu H, Chen Z, Knisely JP, Nath R, Feng Z, Bao S, Deng J. Concomitant Imaging Dose and Cancer Risk in Image Guided Thoracic Radiation Therapy. International Journal Of Radiation Oncology • Biology • Physics 2015, 93: 523-531. PMID: 26460994, DOI: 10.1016/j.ijrobp.2015.06.034.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAgedAged, 80 and overAorta, ThoracicBody SizeBreastChildChild, PreschoolCone-Beam Computed TomographyFemaleHeartHumansLungMaleMiddle AgedMonte Carlo MethodOrgans at RiskPhantoms, ImagingPhotonsPrecision MedicineProtonsRadiation DosageRadiography, ThoracicRadiotherapy, Image-GuidedRisk AssessmentSex FactorsSpinal CordThoracic WallThoraxConceptsConcomitant imaging doseThoracic radiation therapyCancer riskRadiation therapyMean dosesCardiac substructuresKilovoltage cone-beamImaging doseAdverse eventsPediatric patientsMedian dosesCancer patientsRight ventricleExtra radiation doseSpinal cordHigh dosesPatientsCone beamPlanning CT imagesChest dimensionsDosesPatient sizeImaging guidanceTherapyDose
2011
Testicular Doses in Image-Guided Radiotherapy of Prostate Cancer
Deng J, Chen Z, Yu JB, Roberts KB, Peschel RE, Nath R. Testicular Doses in Image-Guided Radiotherapy of Prostate Cancer. International Journal Of Radiation Oncology • Biology • Physics 2011, 82: e39-e47. PMID: 21489702, DOI: 10.1016/j.ijrobp.2011.01.071.Peer-Reviewed Original ResearchConceptsImage-guided radiotherapyTesticular dosesFull-fan modeProstate cancerFemoral headLess doseCBCT scansHalf-fan modeProstate cancer patientsKilovoltage cone-beamCancer patientsIntensity-modulated radiotherapy (IMRT) treatmentKilovoltage CBCTSuperior-inferior directionCone beamDosesCBCT fieldProstate patientsRectumDoseProstateMore doseRadiotherapy treatmentPatientsRadiotherapyKilovoltage Imaging Doses in the Radiotherapy of Pediatric Cancer Patients
Deng J, Chen Z, Roberts KB, Nath R. Kilovoltage Imaging Doses in the Radiotherapy of Pediatric Cancer Patients. International Journal Of Radiation Oncology • Biology • Physics 2011, 82: 1680-1688. PMID: 21477943, DOI: 10.1016/j.ijrobp.2011.01.062.Peer-Reviewed Original ResearchConceptsPediatric cancer patientsCancer patientsTesticular shieldingSpinal cordKilovoltage cone-beamCBCT dosesMean dosesClinical conditionsDose reductionLarge dosesFemoral headPatientsCBCT scansCone beamDosesFull-fan modeOptical nerveCBCT fieldCordDose increaseImaging dosesScanning protocolOARsRadiotherapyHalf-fan mode
2008
Clinical implementation of enhanced dynamic wedges into the Pinnacle treatment planning system: Monte Carlo validation and patient-specific QA
Ahmad M, Deng J, Lund MW, Chen Z, Kimmett J, Moran MS, Nath R. Clinical implementation of enhanced dynamic wedges into the Pinnacle treatment planning system: Monte Carlo validation and patient-specific QA. Physics In Medicine And Biology 2008, 54: 447-465. PMID: 19098353, DOI: 10.1088/0031-9155/54/2/018.Peer-Reviewed Original ResearchIce as a water-equivalent solid medium for brachytherapy dosimetric measurements
Song H, Chen Z, Yue N, Wu Q, Yin FF. Ice as a water-equivalent solid medium for brachytherapy dosimetric measurements. Radiation And Environmental Biophysics 2008, 48: 145-151. PMID: 19066926, DOI: 10.1007/s00411-008-0205-9.Peer-Reviewed Original ResearchConceptsSolid phantomWater conversion factorNon-negligible uncertaintiesMono-energetic photonsPrecise positioningLow-energy photon-emitting brachytherapy sourcesChemical compositionBrachytherapy sourcesPositioning advantageDosimetric measurementsExperimental determinationNecessary precisionDosimetric characteristicsPhantomIceBrachytherapy dosimetryPositioningConversion factorPhotonsUncertaintyKeVEvaluation of an electron Monte Carlo dose calculation algorithm for electron beams
Hu YA, Song H, Chen Z, Zhou S, Yin F. Evaluation of an electron Monte Carlo dose calculation algorithm for electron beams. Journal Of Applied Clinical Medical Physics 2008, 9: 1-15. PMID: 18716583, PMCID: PMC5722292, DOI: 10.1120/jacmp.v9i3.2720.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsElectronsMonte Carlo MethodParticle AcceleratorsRadiotherapy Planning, Computer-AssistedConceptsElectron Monte Carlo dose calculation algorithmMonte Carlo dose calculation algorithmGrid sizeDose calculation algorithmCalculation grid sizeCalculation algorithmEMC algorithmElectron beamMonte Carlo simulationsElectron beam directionMeasurement dataCutout factorsCalculation iterationsCarlo simulationsDose distributionMeV electron beamLinac headBeam characteristicsBeam dataBeam directionMinimal measurementsMaximum discrepancyAlgorithmDose calculationsBeam
2005
Dose rate constant of a Cesium‐131 interstitial brachytherapy seed measured by thermoluminescent dosimetry and gamma‐ray spectrometry
Chen Z, Bongiorni P, Nath R. Dose rate constant of a Cesium‐131 interstitial brachytherapy seed measured by thermoluminescent dosimetry and gamma‐ray spectrometry. Medical Physics 2005, 32: 3279-3285. PMID: 16372409, DOI: 10.1118/1.2098127.Peer-Reviewed Original Research
2001
Dose rate constant and energy spectrum of interstitial brachytherapy sources
Chen Z, Nath R. Dose rate constant and energy spectrum of interstitial brachytherapy sources. Medical Physics 2001, 28: 86-96. PMID: 11213926, DOI: 10.1118/1.1333748.Peer-Reviewed Original Research