2017
Incorporating patient-specific CT-based ophthalmic anatomy in modeling iodine-125 eye plaque brachytherapy dose distributions
Tien CJ, Astrahan MA, Kim JM, Materin M, Chen Z, Nath R, Liu W. Incorporating patient-specific CT-based ophthalmic anatomy in modeling iodine-125 eye plaque brachytherapy dose distributions. Brachytherapy 2017, 16: 1057-1064. PMID: 28778599, DOI: 10.1016/j.brachy.2017.06.014.Peer-Reviewed Original ResearchMeSH KeywordsBrachytherapyEye NeoplasmsHumansIodine RadioisotopesOphthalmoscopyRadiotherapy DosageRadiotherapy Planning, Computer-AssistedTomography, X-Ray ComputedConceptsEye modelDisc distanceDose differenceTumor apexPrescription doseOcular parametersPlaque SimulatorOcular structuresSubstantial dose differencesTarget volumePlaque positionDosimetric parametersPatientsClinical planningDosimetric impactSignificant differencesBrachytherapy planningSeed strengthPlaquesBrachytherapy dose distributionsDose distributionPatient-specific modelsDifferencesTumorsRetina
2011
An integrated approach to segmentation and nonrigid registration for application in image-guided pelvic radiotherapy
Lu C, Chelikani S, Papademetris X, Knisely JP, Milosevic MF, Chen Z, Jaffray DA, Staib LH, Duncan JS. An integrated approach to segmentation and nonrigid registration for application in image-guided pelvic radiotherapy. Medical Image Analysis 2011, 15: 772-785. PMID: 21646038, PMCID: PMC3164526, DOI: 10.1016/j.media.2011.05.010.Peer-Reviewed Original ResearchAlgorithmsBayes TheoremFemaleHumansImaging, Three-DimensionalMaleProstatic NeoplasmsRadiographic Image EnhancementRadiographic Image Interpretation, Computer-AssistedRadiotherapy, Computer-AssistedReproducibility of ResultsSensitivity and SpecificitySubtraction TechniqueSystems IntegrationTomography, X-Ray ComputedUterine Cervical Neoplasms
2010
Response to “Comment on ‘AAPM recommendations on dose prescription and reporting methods for permanent interstitial brachytherapy for prostate cancer: Report of Task Group 137’” [Med. Phys. 36, 5310–5322 (2009)]
Nath R, Bice WS, Butler WM, Chen Z, Meigooni AS, Narayana V, Rivard MJ, Yu Y. Response to “Comment on ‘AAPM recommendations on dose prescription and reporting methods for permanent interstitial brachytherapy for prostate cancer: Report of Task Group 137’” [Med. Phys. 36, 5310–5322 (2009)]. Medical Physics 2010, 37: 1933-1933. PMID: 20443515, DOI: 10.1118/1.3358143.Peer-Reviewed Original ResearchIntegrated Segmentation and Nonrigid Registration for Application in Prostate Image-Guided Radiotherapy
Lu C, Chelikani S, Chen Z, Papademetris X, Staib LH, Duncan JS. Integrated Segmentation and Nonrigid Registration for Application in Prostate Image-Guided Radiotherapy. Lecture Notes In Computer Science 2010, 13: 53-60. PMID: 20879214, DOI: 10.1007/978-3-642-15705-9_7.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsHumansImaging, Three-DimensionalMaleProstatic NeoplasmsRadiographic Image EnhancementRadiographic Image Interpretation, Computer-AssistedRadiotherapy, Computer-AssistedReproducibility of ResultsSensitivity and SpecificitySubtraction TechniqueSystems IntegrationTomography, X-Ray ComputedConceptsManual segmentationAutomatic segmentationImportant treatment parametersNonrigid registrationImage-guided radiotherapy systemReal patient dataNon-rigid registrationIntegrated SegmentationRegistration partRadiotherapy linear acceleratorSegmentationTreatment imagesImage qualityCone-beam CTTreatment parametersImagesPromising resultsPatient dataKey anatomical structuresLinear acceleratorRegistrationPrevious workRadiotherapy system
2009
AAPM recommendations on dose prescription and reporting methods for permanent interstitial brachytherapy for prostate cancer: Report of Task Group 137
Nath R, Bice WS, Butler WM, Chen Z, Meigooni AS, Narayana V, Rivard MJ, Yu Y. AAPM recommendations on dose prescription and reporting methods for permanent interstitial brachytherapy for prostate cancer: Report of Task Group 137. Medical Physics 2009, 36: 5310-5322. PMID: 19994539, PMCID: PMC2776817, DOI: 10.1118/1.3246613.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsBrachytherapyHumansIntraoperative CareMagnetic Resonance ImagingMaleModels, BiologicalProstatic NeoplasmsRadiometryRadiotherapy DosageTime FactorsTomography, X-Ray ComputedConceptsBiological equivalent doseTumor volumeDose prescriptionStandard of careProstate cancer patientsPermanent interstitial brachytherapyAcute single dosesEffects of edemaCancer patientsSurgical traumaIntraoperative implantationSingle dosesClinical trialsProstate cancerRadiobiological modelsCurrent recommendationsInterstitial brachytherapyMore specific guidelinesRoutine patient treatmentsDifferent dose distributionsTreatment planPatient treatmentTarget volumeMost implantsDose distributionConstrained non-rigid registration for use in image-guided adaptive radiotherapy
Greene WH, Chelikani S, Purushothaman K, Knisely JP, Chen Z, Papademetris X, Staib LH, Duncan JS. Constrained non-rigid registration for use in image-guided adaptive radiotherapy. Medical Image Analysis 2009, 13: 809-817. PMID: 19682945, PMCID: PMC2771756, DOI: 10.1016/j.media.2009.07.004.Peer-Reviewed Original ResearchAlgorithmsArtificial IntelligenceHumansMalePattern Recognition, AutomatedProstatic NeoplasmsRadiographic Image EnhancementRadiographic Image Interpretation, Computer-AssistedRadiotherapy, Computer-AssistedRadiotherapy, ConformalReproducibility of ResultsSensitivity and SpecificitySubtraction TechniqueTomography, X-Ray Computed
2008
Automated 2D–3D registration of portal images and CT data using line‐segment enhancement
Munbodh R, Chen Z, Jaffray DA, Moseley DJ, Knisely JP, Duncan JS. Automated 2D–3D registration of portal images and CT data using line‐segment enhancement. Medical Physics 2008, 35: 4352-4361. PMID: 18975681, PMCID: PMC3910153, DOI: 10.1118/1.2975143.Peer-Reviewed Original ResearchAlgorithmsArtificial IntelligenceHumansImaging, Three-DimensionalMalePattern Recognition, AutomatedProstatic NeoplasmsRadiographic Image EnhancementRadiographic Image Interpretation, Computer-AssistedRadiotherapy, Computer-AssistedReproducibility of ResultsSensitivity and SpecificitySubtraction TechniqueTomography, X-Ray ComputedA Constrained Non-rigid Registration Algorithm for Use in Prostate Image-Guided Radiotherapy
Greene W, Chelikani S, Purushothaman K, Chen Z, Knisely J, Staib L, Papademetris X, Duncan J. A Constrained Non-rigid Registration Algorithm for Use in Prostate Image-Guided Radiotherapy. Lecture Notes In Computer Science 2008, 11: 780-788. PMID: 18979817, PMCID: PMC2790815, DOI: 10.1007/978-3-540-85988-8_93.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsArtificial IntelligenceHumansImaging, Three-DimensionalMalePattern Recognition, AutomatedProstatic NeoplasmsRadiographic Image EnhancementRadiographic Image Interpretation, Computer-AssistedRadiotherapy, Computer-AssistedReproducibility of ResultsSensitivity and SpecificitySubtraction TechniqueTomography, X-Ray ComputedConceptsTreatment planProstate image-guided radiotherapyOriginal treatment planRadiation dosageImage-guided radiotherapyTreatment daysRadiotherapy treatment plansCritical organsDifferent patientsPatient dataDifferent treatment daysBladderRectumProstateFemurBone motionCT imagesDosageReal patient dataPatientsRadiotherapy
2004
A technique to re-establish dose distributions for previously treated brain cancer patients in external beam radiotherapy
Yue NJ, Knisely JP, Studholme C, Chen Z, Bond JE, Nath R. A technique to re-establish dose distributions for previously treated brain cancer patients in external beam radiotherapy. Medical Dosimetry 2004, 29: 31-41. PMID: 15023391, DOI: 10.1016/j.meddos.2003.09.004.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsBrain NeoplasmsHumansNeoplasm Recurrence, LocalRadiotherapy DosageRadiotherapy Planning, Computer-AssistedRetreatmentTomography, X-Ray ComputedConceptsPrevious treatmentCurrent treatmentTreatment planPrevious treatment sessionTime of reirradiationCurrent treatment planExternal beam radiotherapyBrain cancer patientsNew treatment planPatient coordinate systemDose distributionPatient anatomyCancer patientsTumor recurrenceCurrent patient anatomyBeam radiotherapyNew tumorsTreatment sessionsTreatment dose distributionsIsocenter coordinatesPatient positionNew patient anatomyBrain treatmentCollimator anglesRadiotherapy treatment
2003
Entropy-Based Dual-Portal-to-3-DCT Registration Incorporating Pixel Correlation
Bansal R, Staib LH, Chen Z, Rangarajan A, Knisely J, Nath R, Duncan JS. Entropy-Based Dual-Portal-to-3-DCT Registration Incorporating Pixel Correlation. IEEE Transactions On Medical Imaging 2003, 22: 29. PMID: 12703758, DOI: 10.1109/tmi.2002.806430.Peer-Reviewed Original ResearchConceptsRegistration frameworkImage dataMutual information-based registration algorithmRegistration parametersPortal imagesUltrasound image dataReal patient dataTomography image dataImage pixelsPixel correlationRegistration algorithmPatient setup verificationSegmentationPixel intensityMarkov random processInitial versionTransformation parametersAppropriate entropyImagesAlgorithmPatient dataFrameworkCT imagesLine processSetup verification
1999
Combined use of transverse and scout computed tomography scans to localize radioactive seeds in an interstitial brachytherapy implant
Yue N, Chen Z, Bond J, Son Y, Nath R. Combined use of transverse and scout computed tomography scans to localize radioactive seeds in an interstitial brachytherapy implant. Medical Physics 1999, 26: 502-505. PMID: 10227350, DOI: 10.1118/1.598548.Peer-Reviewed Original ResearchA minimax entropy registration framework for patient setup verification in radiotherapy
Bansal R, Staib L, Chen Z, Rangarajan A, Knisely J, Nath R, Duncan J. A minimax entropy registration framework for patient setup verification in radiotherapy. Computer Assisted Surgery 1999, 4: 287-304. PMID: 10631372, DOI: 10.1002/(sici)1097-0150(1999)4:6<287::aid-igs1>3.0.co;2-9.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsEntropyHumansModels, TheoreticalPhantoms, ImagingRadiotherapyTomography, X-Ray Computed