2007
On the Need to Compensate for Edema-Induced Dose Reductions in Preplanned 131Cs Prostate Brachytherapy
Chen ZJ, Deng J, Roberts K, Nath R. On the Need to Compensate for Edema-Induced Dose Reductions in Preplanned 131Cs Prostate Brachytherapy. International Journal Of Radiation Oncology • Biology • Physics 2007, 70: 303-310. PMID: 17980500, PMCID: PMC2289996, DOI: 10.1016/j.ijrobp.2007.09.007.Peer-Reviewed Original ResearchConceptsDose reductionProstate brachytherapyDose compensationLarge edemaBiochemical recurrence-free survivalRecurrence-free survivalSignificant dose reductionEffects of edemaSublethal damage repairAdditional irradiationPrescription doseProstate cancerIndividual patientsEdemaEdema evolutionPrescribed doseProstate edemaEffective doseRadiobiologic effectsBrachytherapyDoseProstate implantsDose responseImplants
2006
Potential impact of prostate edema on the dosimetry of permanent seed implants using the new (model CS‐1) seeds
Chen Z, Deng J, Roberts K, Nath R. Potential impact of prostate edema on the dosimetry of permanent seed implants using the new (model CS‐1) seeds. Medical Physics 2006, 33: 968-975. PMID: 16696473, DOI: 10.1118/1.2179170.Peer-Reviewed Original Research
2005
Relative Biological Effectiveness of 103Pd and 125I Photons for Continuous Low-Dose-Rate Irradiation of Chinese Hamster Cells
Nath R, Bongiorni P, Chen Z, Gragnano J, Rockwell S. Relative Biological Effectiveness of 103Pd and 125I Photons for Continuous Low-Dose-Rate Irradiation of Chinese Hamster Cells. Radiation Research 2005, 163: 501-509. PMID: 15850411, DOI: 10.1667/rr3363.Peer-Reviewed Original ResearchConceptsContinuous low doseRate irradiationDose-rate effectInverse dose-rate effectCGy/hInitial dose rateChinese hamster lung cellsHigher initial dose rateLow doseHamster lung cellsLung cellsDose rateCell survivalX-ray beamRelative biological effectivenessChinese hamster cellsCellsImplantsAverage RBEHamster cellsBiological responsesBiological effectivenessMonoenergetic X-ray beam
2000
Dosimetric effects of needle divergence in prostate seed implant using and radioactive seeds
Nath S, Chen Z, Yue N, Trumpore S, Peschel R. Dosimetric effects of needle divergence in prostate seed implant using and radioactive seeds. Medical Physics 2000, 27: 1058-1066. PMID: 10841410, DOI: 10.1118/1.598971.Peer-Reviewed Original ResearchConceptsMinimum target doseIodine-125 implantsTarget doseDose coverageTumor biological effective doseTarget dose coverageBiological effective doseBase of prostateRadioactive seedsProstate seed implantsProstate seedPalladium-103Target volumeEffective doseDosimetric qualityDosePatient implantsDosimetric effectsSeed implantsProstateImplantsMagnitude of degradationActual implantationNeedle orientationActual configuration