Rapid enhancement of beta 2-interferon/B-cell differentiation factor BSF-2 gene expression in human fibroblasts by diacylglycerols and the calcium ionophore A23187.
Sehgal PB, Walther Z, Tamm I. Rapid enhancement of beta 2-interferon/B-cell differentiation factor BSF-2 gene expression in human fibroblasts by diacylglycerols and the calcium ionophore A23187. Proceedings Of The National Academy Of Sciences Of The United States Of America 1987, 84: 3663-3667. PMID: 3108877, PMCID: PMC304935, DOI: 10.1073/pnas.84.11.3663.Peer-Reviewed Original ResearchMeSH KeywordsAntigens, Differentiation, B-LymphocyteAntigens, SurfaceB-LymphocytesCalcimycinCells, CulturedDiglyceridesFibroblastsGenesGlyceridesHumansInterferon Type IRNA, MessengerTranscription, GeneticConceptsGene expressionProtein kinase CProtein kinaseIFN-beta 2Cyclic nucleotide-dependent protein kinasesHuman fibroblastsFS-4 cellsKinase CCGMP-dependent protein kinaseRate of transcriptionProtein kinase C pathwayKinase C pathwayMRNA levelsFS-4 fibroblastsGene transcriptionVesicular stomatitis virusMin of additionCell growthGenesStomatitis virusC pathwayTranscriptionDiacylglycerolSynthetic diacylglycerolKinase