1988
Transcriptional regulation of the interferon-beta 2/B cell differentiation factor BSF-2/hepatocyte-stimulating factor gene in human fibroblasts by other cytokines.
Walther Z, May LT, Sehgal PB. Transcriptional regulation of the interferon-beta 2/B cell differentiation factor BSF-2/hepatocyte-stimulating factor gene in human fibroblasts by other cytokines. The Journal Of Immunology 1988, 140: 974-7. PMID: 3276786, DOI: 10.4049/jimmunol.140.3.974.Peer-Reviewed Original ResearchConceptsPlatelet-derived growth factorIL-1 alphaGene transcriptionIFN-beta 1IFN-beta 2 mRNAIL-1 alpha inductionIL-1 alpha-treated cellsAlpha-treated cellsHuman diploid fibroblastsTranscriptional regulationCycloheximide-treated cellsTranscription assaysEnhance transcriptionConfluent quiescent culturesTranscriptional levelFactor genesTranscriptional activityNuclear runFS-4 cellsTranscriptionGene 2Levels of mRNAHepatocyte-stimulating factorDiploid fibroblastsGenes
1987
Rapid enhancement of beta 2-interferon/B-cell differentiation factor BSF-2 gene expression in human fibroblasts by diacylglycerols and the calcium ionophore A23187.
Sehgal PB, Walther Z, Tamm I. Rapid enhancement of beta 2-interferon/B-cell differentiation factor BSF-2 gene expression in human fibroblasts by diacylglycerols and the calcium ionophore A23187. Proceedings Of The National Academy Of Sciences Of The United States Of America 1987, 84: 3663-3667. PMID: 3108877, PMCID: PMC304935, DOI: 10.1073/pnas.84.11.3663.Peer-Reviewed Original ResearchConceptsGene expressionProtein kinase CProtein kinaseIFN-beta 2Cyclic nucleotide-dependent protein kinasesHuman fibroblastsFS-4 cellsKinase CCGMP-dependent protein kinaseRate of transcriptionProtein kinase C pathwayKinase C pathwayMRNA levelsFS-4 fibroblastsGene transcriptionVesicular stomatitis virusMin of additionCell growthGenesStomatitis virusC pathwayTranscriptionDiacylglycerolSynthetic diacylglycerolKinase