Crystal structure and conformation of a DNA–RNA hybrid duplex with a polypurine RNA strand: d(TTCTTBr5CTTC)–r(GAAGAAGAA)
Xiong Y, Sundaralingam M. Crystal structure and conformation of a DNA–RNA hybrid duplex with a polypurine RNA strand: d(TTCTTBr5CTTC)–r(GAAGAAGAA). Structure 1998, 6: 1493-1501. PMID: 9862803, DOI: 10.1016/s0969-2126(98)00148-8.Peer-Reviewed Original ResearchConceptsDNA-RNA hybrid duplexesRNA strandHybrid duplexesPolypurine tractDNA-RNA hybridsForm conformationMolecular replacement methodMinor groove sideRNA genomeShort stretchesBase pairsPlus-strand DNA synthesisRNase H activityDNA strandsTerminal base pairsRNase HSugar-phosphate backboneDNA synthesisRNase H.U3 region