2024
Incorporating prior information in gene expression network-based cancer heterogeneity analysis
Li R, Xu S, Li Y, Tang Z, Feng D, Cai J, Ma S. Incorporating prior information in gene expression network-based cancer heterogeneity analysis. Biostatistics 2024, kxae028. PMID: 39074174, DOI: 10.1093/biostatistics/kxae028.Peer-Reviewed Original Research
2023
ZINBMM: a general mixture model for simultaneous clustering and gene selection using single-cell transcriptomic data
Li Y, Wu M, Ma S, Wu M. ZINBMM: a general mixture model for simultaneous clustering and gene selection using single-cell transcriptomic data. Genome Biology 2023, 24: 208. PMID: 37697330, PMCID: PMC10496184, DOI: 10.1186/s13059-023-03046-0.Peer-Reviewed Original ResearchConceptsSingle-cell transcriptomic dataCell heterogeneitySingle-cell RNA sequencing data analysisRNA sequencing data analysisCluster-specific genesGene selectionScRNA-seq datasetsSequencing data analysisNegative binomial mixture modelTranscriptomic dataCell lineagesCell typesBinomial mixture modelsBiological understandingBatch effectsDropout eventsLineagesGenesRaw countsCritical componentSelectionSystemic analysis