L-Selectin-Dependent Lymphoid Occupancy Is Required to Induce Alloantigen-Specific Tolerance
Bai Y, Liu J, Wang Y, Honig S, Qin L, Boros P, Bromberg JS. L-Selectin-Dependent Lymphoid Occupancy Is Required to Induce Alloantigen-Specific Tolerance. The Journal Of Immunology 2002, 168: 1579-1589. PMID: 11823485, DOI: 10.4049/jimmunol.168.4.1579.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, MonoclonalCell MovementCells, CulturedFingolimod HydrochlorideGraft SurvivalHeart TransplantationImmunosuppressive AgentsIsoantigensKineticsL-SelectinLymph NodesLymphocyte ActivationLymphoid TissueMiceMice, KnockoutPropylene GlycolsSphingosineSpleenT-LymphocytesTransplantation ToleranceConceptsAlloantigen-specific toleranceIndefinite allograft survivalAllograft survivalLymph nodesT cellsLymph node homingSecondary lymphoid organsWild-type recipientsImmunosuppressive regimenPeripheral tolerizationCardiac allograftsAdoptive transferConcurrent administrationPeripheral bloodLymphoid organsLymphoid tissueHistologic examinationHoming receptorImmune regulationT lymphocytesTolerizationAg processingAlloantigensImmunosuppressantsLymphocytes