2024
Social isolation and likelihood of becoming centenarians: evidence from the Chinese longitudinal healthy longevity survey
Li Y, Jigeer G, Lv Y, Wang K, Peng Y, Sun L, Shi X, Gao X. Social isolation and likelihood of becoming centenarians: evidence from the Chinese longitudinal healthy longevity survey. BMC Geriatrics 2024, 24: 839. PMID: 39407128, PMCID: PMC11476547, DOI: 10.1186/s12877-024-05417-z.Peer-Reviewed Original ResearchConceptsChinese Longitudinal Healthy Longevity SurveySocial isolationLongevity SurveyAssociated with health outcomesHigher social isolation scoresConditional logistic regression modelsOldest-old peopleProspective nested case-control studyPublic health initiativesSocial isolation scoresOldest-old populationNested case-control studyDegree of social isolationLogistic regression modelsCase-control studyBackgroundSocial isolationHealth initiativesHealth outcomesLifestyle factorsCommunity-basedNever smokersOlder adultsYear of entryInverse associationIsolation scoresExposome-Wide Ranking to Uncover Environmental Chemicals Associated with Dyslipidemia: A Panel Study in Healthy Older Chinese Adults from the BAPE Study.
Ding E, Deng F, Fang J, Liu J, Yan W, Yao Q, Miao K, Wang Y, Sun P, Li C, Liu Y, Dong H, Dong L, Zhang X, Lu Y, Lin X, Ding C, Li T, Shi Y, Cai Y, Liu X, Godri Pollitt K, Ji J, Tong S, Tang S, Shi X. Exposome-Wide Ranking to Uncover Environmental Chemicals Associated with Dyslipidemia: A Panel Study in Healthy Older Chinese Adults from the BAPE Study. Environmental Health Perspectives 2024, 132: 97005. PMID: 39240788, PMCID: PMC11379127, DOI: 10.1289/ehp13864.Peer-Reviewed Original ResearchConceptsDyslipidemia markersCardiovascular diseaseMulti-omicsMarkers of dyslipidemiaExamination of cytokinesMeasurement of cytokinesSerum lipidomeSystemic inflammationMulti-omics profilingCardiac functionDyslipidemiaPrimary preventionClinical measuresSerumChinese adultsBlood transcriptomeImpact spectraCytokinesExposome-wide association studyInflammationMarkersBiomolecular pathwaysAssociationHealthy older adultsElectrocardiogramAssociation between dietary diversity changes and frailty among Chinese older adults: findings from a nationwide cohort study
Wang X, Zhong W, Zhang Y, Xiang J, Chen H, Li Z, Shen Q, Shen D, Song W, Fu Q, Gao J, Chen Z, Li C, Xie J, Liu D, Lv Y, Shi X, Mao C. Association between dietary diversity changes and frailty among Chinese older adults: findings from a nationwide cohort study. Nutrition Journal 2024, 23: 91. PMID: 39138490, PMCID: PMC11320915, DOI: 10.1186/s12937-024-00997-3.Peer-Reviewed Original ResearchConceptsDietary diversity scoreRisk of frailtyChinese older adultsOlder adultsSelf-reported health itemsChinese Longitudinal Healthy Longevity SurveyHigher risk of frailtyIncreased risk of frailtyOlder Chinese adultsFollow-up surveyNationwide cohort studyCox proportional hazards modelsHealth itemsLongevity SurveyFrailty incidencePrevent frailtyProportional hazards modelBackgroundDietary diversityChinese adultsFood groupsAssess frailtyPotential preventive measuresDiversity scoreComparing scoresCohort studyAssociation between Personal Abiotic Airborne Exposures and Body Composition Changes among Healthy Adults (60–69 Years Old): A Combined Exposome-Wide and Lipidome Mediation Approach from the China BAPE Study
Sun P, Guo X, Ding E, Li C, Ren H, Xu Y, Qian J, Deng F, Shi W, Dong H, Lin E, Guo P, Fang J, Zhang Q, Zhao W, Tong S, Lu X, Pollitt K, Shi X, Tang S. Association between Personal Abiotic Airborne Exposures and Body Composition Changes among Healthy Adults (60–69 Years Old): A Combined Exposome-Wide and Lipidome Mediation Approach from the China BAPE Study. Environmental Health Perspectives 2024, 132: 077005. PMID: 39028628, PMCID: PMC11259245, DOI: 10.1289/ehp13865.Peer-Reviewed Original ResearchConceptsFat mass indicatorsHealthy older adultsBayesian kernel machine regressionVisceral fat areaOlder adultsPercent body fatBody compositionBody fat massExposome-wide association studyPrevention of chronic diseasesAir pollution exposureBody composition indicatorsMediation analysisInBody 770 deviceHealthy adultsAssociated with increased body fat massBody composition changesKernel machine regressionBayesian kernel machine regression modelsChronic diseasesPollution exposureBody fatAssociation studiesAdverse health effectsFat area[Prediction model related to 6-year risk of frailty in older adults aged 65 years or above in China].
Zhou J, Qi L, Wang J, Liu S, Shi W, Ye L, Zhang Z, Zhang Z, Meng X, Cui J, Chen C, Lyu Y, Shi X. [Prediction model related to 6-year risk of frailty in older adults aged 65 years or above in China]. Chinese Journal Of Epidemiology 2024, 45: 809-816. PMID: 38889980, DOI: 10.3760/cma.j.cn112338-20231205-00333.Peer-Reviewed Original ResearchConceptsDaily living scoresPredictors of frailtyArea under the receiver operating characteristic curveIncident frailtyOlder adultsLiving scoresChinese Longitudinal Healthy Longevity SurveyRisk thresholdSelf-rated healthChinese older adultsRisk of incident frailtyRisk of frailtyFree of frailtyPhysical examination variablesCox proportional hazards regression modelsProportional hazards regression modelsRisk prediction modelInstrumental activitiesHazards regression modelsLongevity SurveyFrailty incidenceFollow-up timeDecision-curve analysisOlder personsReceiver operating characteristic curve[Exploring implementation strategies for healthy longevity among the elderly population in China based on the delphi method].
Chai X, Cui J, Ye L, Lyu Y, Shao R, Zhang J, Shi X. [Exploring implementation strategies for healthy longevity among the elderly population in China based on the delphi method]. Chinese Preventive Medicine 2024, 58: 883-890. PMID: 38955737, DOI: 10.3760/cma.j.cn112150-20230804-00056.Peer-Reviewed Original ResearchConceptsHarmony coefficientsImplementation strategiesHealthy longevityAuthority coefficientPromote healthy longevityExpert active coefficientElderly populationChinese elderly populationDelphi methodDelphi consultationConsultation questionnaireElderly care service industryPublic healthFeasibility scoreScore of feasibilityAverage scoreConsultationExpert discussionScoresLiterature reviewClinical medicineHealthy Lifestyle and the Likelihood of Becoming a Centenarian
Li Y, Wang K, Jigeer G, Jensen G, Tucker K, Lv Y, Shi X, Gao X. Healthy Lifestyle and the Likelihood of Becoming a Centenarian. JAMA Network Open 2024, 7: e2417931. PMID: 38900423, PMCID: PMC11190803, DOI: 10.1001/jamanetworkopen.2024.17931.Peer-Reviewed Original ResearchConceptsHealthy lifestyleCase-control studyLifestyle factorsOlder adultsChinese Longitudinal Healthy Longevity SurveySelf-reported chronic conditionsHealthy lifestyle scoreImprove lifestyle behaviorsChinese older adultsAssociated with life expectancyProspective nested case-control studyNested case-control studyLifestyle scoreLifestyle behaviorsLongevity SurveyOlder age groupsHealth outcomesChronic conditionsSociodemographic characteristicsCommunity-basedMental wellnessYear of entryMain OutcomesOdds ratioMiddle-aged[Exploring a definition of healthy longevity in Chinese population based on Delphi method].
Chai X, Cui J, Ye L, Zhou J, Shao R, Shi X, Lyu Y, Zhang J. [Exploring a definition of healthy longevity in Chinese population based on Delphi method]. Chinese Preventive Medicine 2024, 58: 629-635. PMID: 38715502, DOI: 10.3760/cma.j.cn112150-20230924-00220.Peer-Reviewed Original ResearchConceptsHealthy longevityMental healthNon-communicable disease indicatorsSelf-rated healthTwo-round Delphi consultationCognitive functionWell-beingChinese populationFunctions of daily lifeHigh disability rateSubjective well-beingGeriatric healthDelphi consultationPhysical healthFunctional abilityHearing functionElderly care service industryDelphi surveyExpert consultationDisability rateHealthPublic healthMeasurement toolsMultiple-choice questionsFamily members[Association of urinary cadmium level with body mass index and body circumferences among older adults over 65 years old in 9 longevity areas of China].
Zhang Z, Wu B, Qu Y, Li Y, Xu L, Lyu C, Chen C, Wang J, Xue K, Wei Y, Zhou J, Zheng X, Qiu Y, Luo Y, Liu J, Lyu Y, Shi X. [Association of urinary cadmium level with body mass index and body circumferences among older adults over 65 years old in 9 longevity areas of China]. Chinese Preventive Medicine 2024, 58: 227-234. PMID: 38387955, DOI: 10.3760/cma.j.cn112150-20230912-00181.Peer-Reviewed Original ResearchConceptsBody mass indexWaist circumferenceHip circumferenceCalf circumferenceOlder adultsBody circumferencesLongevity areasUrinary cadmium levelsLinear regression modelsMultiple linear regression modelUrinary cadmium concentrationCadmium levelsUrinary cadmiumAssociated with decreased BMIChange of body mass indexCadmium concentrationsRegression modelsSocio-demographic characteristicsRestricted cubic spline curvesRestricted cubic splinesAge of subjectsBiomarkers Cohort StudyHealth statusNegative linear associationWaistAssociations between serum per- and polyfluoroalkyl substances and thyroid hormones in Chinese adults: A nationally representative cross-sectional study
Xing Y, Li Z, Wang J, Qu Y, Hu Q, Ji S, Chang X, Zhao F, Lv Y, Pan Y, Shi X, Dai J. Associations between serum per- and polyfluoroalkyl substances and thyroid hormones in Chinese adults: A nationally representative cross-sectional study. Environment International 2024, 184: 108459. PMID: 38320373, DOI: 10.1016/j.envint.2024.108459.Peer-Reviewed Original ResearchConceptsRestricted cubic splinesBayesian kernel machine regressionNationally representative cross-sectional studyNonlinear dose-response associationDose-response associationChinese adult populationWeighted multiple linear regressionGeneral Chinese populationCross-sectional studyNationally representative dataYounger age groupsKernel machine regressionChinese adultsInverse associationG-computationPerfluoroheptane sulfonic acidQuantile-based g-computationAdult populationRepresentative dataSignificant associationPositive associationThyroid homeostasisChinese populationMultiple linear regressionAge groupsMediating Role of Liver Dysfunction in the Association between Arsenic Exposure and Diabetes in Chinese Adults: A Nationwide Cross-Sectional Study of China National Human Biomonitoring (CNHBM) 2017–2018
Ji S, Qu Y, Sun Q, Zhao F, Qiu Y, Li Z, Li Y, Song H, Zhang M, Zhang W, Fu H, Cai J, Zhang Z, Zhu Y, Cao Z, Lv Y, Shi X. Mediating Role of Liver Dysfunction in the Association between Arsenic Exposure and Diabetes in Chinese Adults: A Nationwide Cross-Sectional Study of China National Human Biomonitoring (CNHBM) 2017–2018. Environmental Science And Technology 2024, 58: 2693-2703. PMID: 38285630, DOI: 10.1021/acs.est.3c08718.Peer-Reviewed Original ResearchConceptsSerum alanine aminotransferaseLiver dysfunctionAlanine aminotransferaseNationwide cross-sectional studyRestricted cubic spline modelsGeneralized linear mixed modelsEffects of liver dysfunctionMediation analysisCross-sectional studyArsenic exposureAspartate aminotransferaseCubic spline modelsHuman biomonitoringAssociated with TADiabetes prevalenceChinese adultsLow-to-moderateLinear mixed modelsUrinary totalLowest quartileAlcohol consumptionLiver diseaseOverall populationDiabetes[Association of lifestyle and apolipoprotein E gene with risk for cognitive frailty in elderly population in China].
Zhong W, Wang X, Song W, Li C, Chen H, Chen Z, Lyu Y, Li Z, Shi X, Mao C. [Association of lifestyle and apolipoprotein E gene with risk for cognitive frailty in elderly population in China]. Chinese Journal Of Epidemiology 2024, 45: 41-47. PMID: 38228523, DOI: 10.3760/cma.j.cn112338-20231027-00254.Peer-Reviewed Original ResearchConceptsCognitive frailtyCox proportional hazards regression modelsProportional hazards regression modelsPhysical activityHazards regression modelsHealthy lifestyleLevels of physical activityChinese Longitudinal Healthy Longevity SurveyElderly populationRegular physical activityDietary diversityLevel of dietary diversityAssociation of lifestyleAPOE geneImpact of lifestyleRegression modelsAdditive interactionAPOE e4 alleleLifestyle scoreCombined lifestyleLongevity SurveyPhysical frailtyStudy participantsElderly personsLifestyle[Association of sleep duration and physical exercise with dyslipidemia in older adults aged 80 years and over in China].
Wu B, Li Y, Xu L, Zhang Z, Zhou J, Wei Y, Chen C, Wang J, Wu C, Li Z, Hu Z, Long F, Wu Y, Hu X, Li K, Li F, Luo Y, Liu Y, Lyu Y, Shi X. [Association of sleep duration and physical exercise with dyslipidemia in older adults aged 80 years and over in China]. Chinese Journal Of Epidemiology 2024, 45: 48-55. PMID: 38228524, DOI: 10.3760/cma.j.cn112338-20231007-00207.Peer-Reviewed Original ResearchConceptsRestricted cubic splinesPhysical exerciseSleep durationPerson yearsDose-response relationshipAssociation of sleep durationPositive dose-response relationshipImpact of sleep durationBlood lipid testRisk of dyslipidemiaAverage sleep durationRestricted cubic spline functionsCompeting risk modelBaseline surveyBiomarkers Cohort StudyCases of dyslipidemiaLipid testingFasting venous blood samplesInteraction of sleep durationCohort studyExerciseCompetitive risk model analysisDemographic characteristicsIncidence densityStudy subjectsVitamin B12 is associated negatively with anemia in older Chinese adults with a low dietary diversity level: evidence from the Healthy Ageing and Biomarkers Cohort Study (HABCS)
Liu L, Zhou J, Chen C, Qu Y, Wang J, Lu F, Liu Y, Cai J, Ji S, Li Y, Gu H, Zhao F, Lyu Y, Shi X. Vitamin B12 is associated negatively with anemia in older Chinese adults with a low dietary diversity level: evidence from the Healthy Ageing and Biomarkers Cohort Study (HABCS). BMC Geriatrics 2024, 24: 18. PMID: 38178043, PMCID: PMC10768404, DOI: 10.1186/s12877-023-04586-7.Peer-Reviewed Original ResearchConceptsVitamin B12 levelsDietary diversity scorePlasma vitamin B12 levelsB12 levelsFood frequency questionnaireDifferent dietary patternsOlder adultsFrequency questionnaireDietary patternsHigh vitamin B12 levelsVitamin B12Low dietary diversity scoreHigh dietary diversity scorePrevalence of anemiaElderly Chinese peopleBiomarker cohort studyOlder Chinese adultsCohort studyAnemia statusDecreased riskMean ageAnemiaChinese adultsConclusionThe relationshipConfounding factorsVitamin C Alleviates the Risk of Gestational Diabetes Mellitus Associated With Exposure to Metals
Wang Y, Wu W, Zhang P, Chen X, Feng Y, Yang H, Jin L, Huang H, Shi X, Wang S, Zhang Y. Vitamin C Alleviates the Risk of Gestational Diabetes Mellitus Associated With Exposure to Metals. Journal Of Diabetes Research 2024, 2024: 1298122. PMID: 39035682, PMCID: PMC11260216, DOI: 10.1155/2024/1298122.Peer-Reviewed Original ResearchConceptsRisk of gestational diabetes mellitusGestational diabetes mellitusVitamin C intakeDietary vitamin C intakeVitamin C supplement useExposure to heavy metalsHeavy metalsC intakeInductively coupled plasma mass spectrometryAssociated with increased risk of GDMGestational diabetes mellitus casesHigher dietary vitamin C intakeUnconditional logistic regression modelsAssociated with increased riskConcentrations of metalsLevels of mercuryExposure to metalsCase-control studyBlood levels of mercuryHigher blood levelsVitamin CVitamin C supplementationAssociated with metalsOxidative stress pathwaysEarly pregnancy
2023
Association of Daytime-Only, Nighttime-Only, and Compound Heat Waves With Preterm Birth by Urban-Rural Area and Regional Socioeconomic Status in China
Guo Y, Chen P, Xie Y, Wang Y, Mu Y, Zhou R, Niu Y, Shi X, Zhu J, Liang J, Liu Q. Association of Daytime-Only, Nighttime-Only, and Compound Heat Waves With Preterm Birth by Urban-Rural Area and Regional Socioeconomic Status in China. JAMA Network Open 2023, 6: e2326987. PMID: 37566422, PMCID: PMC10422195, DOI: 10.1001/jamanetworkopen.2023.26987.Peer-Reviewed Original ResearchConceptsCase-crossover studySocioeconomic statusPreterm birthNational Maternal Near Miss Surveillance SystemChina's National Maternal Near Miss Surveillance SystemRegional socioeconomic statusSingleton live birthsAssociated with higher riskAssociated with preterm birthGestational ageUrban-rural areasUrban-rural communitiesMaternal healthSingleton birthsMain OutcomesHeat wave exposureCompound heat wavesSocioeconomic regionsWeeks of gestationOdds ratioBirth dataMaternal ageConsecutive daysRural populationSurveillance system