Social isolation and likelihood of becoming centenarians: evidence from the Chinese longitudinal healthy longevity survey
Li Y, Jigeer G, Lv Y, Wang K, Peng Y, Sun L, Shi X, Gao X. Social isolation and likelihood of becoming centenarians: evidence from the Chinese longitudinal healthy longevity survey. BMC Geriatrics 2024, 24: 839. PMID: 39407128, PMCID: PMC11476547, DOI: 10.1186/s12877-024-05417-z.Peer-Reviewed Original ResearchConceptsChinese Longitudinal Healthy Longevity SurveySocial isolationLongevity SurveyAssociated with health outcomesHigher social isolation scoresConditional logistic regression modelsOldest-old peopleProspective nested case-control studyPublic health initiativesSocial isolation scoresOldest-old populationNested case-control studyDegree of social isolationLogistic regression modelsCase-control studyBackgroundSocial isolationHealth initiativesHealth outcomesLifestyle factorsCommunity-basedNever smokersOlder adultsYear of entryInverse associationIsolation scoresLeisure-time activities and disability among Chinese community-dwelling oldest old: evidence from the Chinese Longitudinal Healthy Longevity Study
Zhong W, Wang X, Liang F, Song W, Chen Z, Li Z, Shen Q, Shen D, Nan Y, Xiang J, Li C, Ye Z, Huang H, Wang J, Lv Y, Shi X, Mao C. Leisure-time activities and disability among Chinese community-dwelling oldest old: evidence from the Chinese Longitudinal Healthy Longevity Study. European Journal Of Public Health 2024, ckae129. PMID: 39254527, DOI: 10.1093/eurpub/ckae129.Peer-Reviewed Original ResearchLeisure-time activitiesRisk of disabilityOlder adultsChinese Longitudinal Healthy Longevity StudyChinese Longitudinal Healthy Longevity SurveyActivities of daily livingChinese community-dwellingCox proportional hazards modelsPublic health problemLeisure-timeLongevity SurveyAcceleration of population agingCommunity-dwellingProportional hazards modelDaily livingPhysical performanceWatching TVHealth problemsFrequent engagementDaily activitiesAffecting disabilityDisabilityHazards modelPopulation agingLongevity StudyAssociation between dietary diversity changes and frailty among Chinese older adults: findings from a nationwide cohort study
Wang X, Zhong W, Zhang Y, Xiang J, Chen H, Li Z, Shen Q, Shen D, Song W, Fu Q, Gao J, Chen Z, Li C, Xie J, Liu D, Lv Y, Shi X, Mao C. Association between dietary diversity changes and frailty among Chinese older adults: findings from a nationwide cohort study. Nutrition Journal 2024, 23: 91. PMID: 39138490, PMCID: PMC11320915, DOI: 10.1186/s12937-024-00997-3.Peer-Reviewed Original ResearchConceptsDietary diversity scoreRisk of frailtyChinese older adultsOlder adultsSelf-reported health itemsChinese Longitudinal Healthy Longevity SurveyHigher risk of frailtyIncreased risk of frailtyOlder Chinese adultsFollow-up surveyNationwide cohort studyCox proportional hazards modelsHealth itemsLongevity SurveyFrailty incidencePrevent frailtyProportional hazards modelBackgroundDietary diversityChinese adultsFood groupsAssess frailtyPotential preventive measuresDiversity scoreComparing scoresCohort studyAssociation between Personal Abiotic Airborne Exposures and Body Composition Changes among Healthy Adults (60–69 Years Old): A Combined Exposome-Wide and Lipidome Mediation Approach from the China BAPE Study
Sun P, Guo X, Ding E, Li C, Ren H, Xu Y, Qian J, Deng F, Shi W, Dong H, Lin E, Guo P, Fang J, Zhang Q, Zhao W, Tong S, Lu X, Pollitt K, Shi X, Tang S. Association between Personal Abiotic Airborne Exposures and Body Composition Changes among Healthy Adults (60–69 Years Old): A Combined Exposome-Wide and Lipidome Mediation Approach from the China BAPE Study. Environmental Health Perspectives 2024, 132: 077005. PMID: 39028628, PMCID: PMC11259245, DOI: 10.1289/ehp13865.Peer-Reviewed Original ResearchConceptsFat mass indicatorsHealthy older adultsBayesian kernel machine regressionVisceral fat areaOlder adultsPercent body fatBody compositionBody fat massExposome-wide association studyPrevention of chronic diseasesAir pollution exposureBody composition indicatorsMediation analysisInBody 770 deviceHealthy adultsAssociated with increased body fat massBody composition changesKernel machine regressionBayesian kernel machine regression modelsChronic diseasesPollution exposureBody fatAssociation studiesAdverse health effectsFat areaAnalysis of changes in social isolation, loneliness, or both, and subsequent cognitive function among older adults: Findings from a nationwide cohort study
Huang Q, Zhang P, Shen D, Gao J, Li Z, Lv Y, Shi X, Mao C. Analysis of changes in social isolation, loneliness, or both, and subsequent cognitive function among older adults: Findings from a nationwide cohort study. Alzheimer's & Dementia 2024, 20: 5674-5683. PMID: 38946708, PMCID: PMC11350036, DOI: 10.1002/alz.14080.Peer-Reviewed Original ResearchAssociated with accelerated cognitive declineCognitive impairment riskPersistent lonelinessSocial isolationCognitive declineOlder adultsImpairment riskChinese Longitudinal Healthy Longevity SurveyIncident cognitive impairmentCognitive impairmentAssociation of changesNationwide cohort studyAccelerated cognitive declineCognitive functionLongevity SurveyCohort studyChanging statusLonelinessRisk factorsRegression modelsTobit regression modelCox modelShort-termRiskAdultsPersonal exposure to airborne organic pollutants and lung function changes among healthy older adults
Guo X, Ren H, Sun P, Ding E, Fang J, Fang K, Ma X, Li C, Li C, Xu Y, Cao K, Lin E, Guo P, Pollitt K, Tong S, Tang S, Shi X. Personal exposure to airborne organic pollutants and lung function changes among healthy older adults. Environmental Research 2024, 258: 119411. PMID: 38876423, DOI: 10.1016/j.envres.2024.119411.Peer-Reviewed Original Research[Prediction model related to 6-year risk of frailty in older adults aged 65 years or above in China].
Zhou J, Qi L, Wang J, Liu S, Shi W, Ye L, Zhang Z, Zhang Z, Meng X, Cui J, Chen C, Lyu Y, Shi X. [Prediction model related to 6-year risk of frailty in older adults aged 65 years or above in China]. Chinese Journal Of Epidemiology 2024, 45: 809-816. PMID: 38889980, DOI: 10.3760/cma.j.cn112338-20231205-00333.Peer-Reviewed Original ResearchConceptsDaily living scoresPredictors of frailtyArea under the receiver operating characteristic curveIncident frailtyOlder adultsLiving scoresChinese Longitudinal Healthy Longevity SurveyRisk thresholdSelf-rated healthChinese older adultsRisk of incident frailtyRisk of frailtyFree of frailtyPhysical examination variablesCox proportional hazards regression modelsProportional hazards regression modelsRisk prediction modelInstrumental activitiesHazards regression modelsLongevity SurveyFrailty incidenceFollow-up timeDecision-curve analysisOlder personsReceiver operating characteristic curveA Prospective Cohort Study of Antimony Exposure and Cognitive Impairment in Older Adults — China, 2017–2021
Qiu Y, Ji S, Chen C, Zhou J, Wang J, Wu B, Wei Y, Li F, Zheng X, Xu L, Zhang Z, Zhao F, Chen G, Ji J, Lyu Y, Tong S, Shi X. A Prospective Cohort Study of Antimony Exposure and Cognitive Impairment in Older Adults — China, 2017–2021. China CDC Weekly 2024, 6: 537-541. PMID: 38933661, PMCID: PMC11196874, DOI: 10.46234/ccdcw2024.104.Peer-Reviewed Original ResearchHealthy Lifestyle and the Likelihood of Becoming a Centenarian
Li Y, Wang K, Jigeer G, Jensen G, Tucker K, Lv Y, Shi X, Gao X. Healthy Lifestyle and the Likelihood of Becoming a Centenarian. JAMA Network Open 2024, 7: e2417931. PMID: 38900423, PMCID: PMC11190803, DOI: 10.1001/jamanetworkopen.2024.17931.Peer-Reviewed Original ResearchConceptsHealthy lifestyleCase-control studyLifestyle factorsOlder adultsChinese Longitudinal Healthy Longevity SurveySelf-reported chronic conditionsHealthy lifestyle scoreImprove lifestyle behaviorsChinese older adultsAssociated with life expectancyProspective nested case-control studyNested case-control studyLifestyle scoreLifestyle behaviorsLongevity SurveyOlder age groupsHealth outcomesChronic conditionsSociodemographic characteristicsCommunity-basedMental wellnessYear of entryMain OutcomesOdds ratioMiddle-agedAssociation between exposure to chemical mixtures and epigenetic ageing biomarkers: Modifying effects of thyroid hormones and physical activity
Shi W, Fang J, Ren H, Sun P, Liu J, Deng F, Zhang S, Wang Q, Wang J, Tong S, Tang S, Shi X. Association between exposure to chemical mixtures and epigenetic ageing biomarkers: Modifying effects of thyroid hormones and physical activity. Journal Of Hazardous Materials 2024, 469: 134009. PMID: 38492399, DOI: 10.1016/j.jhazmat.2024.134009.Peer-Reviewed Original ResearchPolycyclic aromatic hydrocarbonsChemical mixture exposureOrganophosphate estersPolyfluoroalkyl substancesMixture exposurePhysical activityAir pollution exposureExposure to chemical mixturesEffects of environmental chemicalsLevels of physical activityAromatic hydrocarbonsPollution exposureHealthy ageing strategiesAged care policyChemical mixturesHealthy older adultsEnvironmental chemicalsEpigenetic ageing biomarkersAdverse effects of environmental chemicalsAcceleration of population agingLifestyle factorsCare policyOlder adultsHormone homeostasisPhthalateAssociations of Low-density Lipoprotein Cholesterol With All-cause and Cause-specific Mortality in Older Adults in China
Ni W, Lv Y, Yuan X, Zhang Y, Zhang H, Zheng Y, Shi X, Xu J. Associations of Low-density Lipoprotein Cholesterol With All-cause and Cause-specific Mortality in Older Adults in China. The Journal Of Clinical Endocrinology & Metabolism 2024, dgae116. PMID: 38436437, DOI: 10.1210/clinem/dgae116.Peer-Reviewed Original ResearchCause-specific mortalityAssociation of low-density lipoprotein cholesterolAll-causeOlder adultsLDL-C levelsLow-density lipoprotein cholesterolAssociated with increased cancer mortalityHazard ratioRisk of all-cause mortalityCVD-specific mortalityLDL-CMultivariable-adjusted HRCardiovascular diseaseProspective cohort studyLipoprotein cholesterolAll-cause mortalityCox proportional hazards modelsOther-cause mortalityHealthy aging researchProportional hazards modelCancer mortalityVital statusMultivariate Cox proportional hazards modelLow LDL-C levelsMedian follow-up time[Association of urinary cadmium level with body mass index and body circumferences among older adults over 65 years old in 9 longevity areas of China].
Zhang Z, Wu B, Qu Y, Li Y, Xu L, Lyu C, Chen C, Wang J, Xue K, Wei Y, Zhou J, Zheng X, Qiu Y, Luo Y, Liu J, Lyu Y, Shi X. [Association of urinary cadmium level with body mass index and body circumferences among older adults over 65 years old in 9 longevity areas of China]. Chinese Preventive Medicine 2024, 58: 227-234. PMID: 38387955, DOI: 10.3760/cma.j.cn112150-20230912-00181.Peer-Reviewed Original ResearchConceptsBody mass indexWaist circumferenceHip circumferenceCalf circumferenceOlder adultsBody circumferencesLongevity areasUrinary cadmium levelsLinear regression modelsMultiple linear regression modelUrinary cadmium concentrationCadmium levelsUrinary cadmiumAssociated with decreased BMIChange of body mass indexCadmium concentrationsRegression modelsSocio-demographic characteristicsRestricted cubic spline curvesRestricted cubic splinesAge of subjectsBiomarkers Cohort StudyHealth statusNegative linear associationWaistSerum 25-Hydroxyvitamin D and Risk of Disability in Activities of Daily Living among the Oldest-Old: An Observational and Mendelian Randomization Study
Li X, Chen C, Zhang Y, Wang J, Cui X, Xu L, Zhou J, Deng L, Zhang M, Lv Y, Yu Q, Shi X. Serum 25-Hydroxyvitamin D and Risk of Disability in Activities of Daily Living among the Oldest-Old: An Observational and Mendelian Randomization Study. Journal Of Nutrition 2024, 154: 1004-1013. PMID: 38246357, DOI: 10.1016/j.tjnut.2024.01.016.Peer-Reviewed Original ResearchActivities of daily livingRisk of disabilityChinese oldest-oldOldest-oldMendelian randomizationDaily livingRisk of ADL disabilityActivities of daily living statusIncidence of physical disabilityBaseline ADL statusSample Mendelian randomizationMendelian randomization studiesGenetic risk scoreInverse causal relationshipPoor health conditionsFollow-up interviewsADL disabilityGenetic instrumentsMR analysisADL statusNonlinear MRSerum 25-hydroxyvitamin DBiomarkers Cohort StudyOlder adultsHealth conditionsVitamin B12 is associated negatively with anemia in older Chinese adults with a low dietary diversity level: evidence from the Healthy Ageing and Biomarkers Cohort Study (HABCS)
Liu L, Zhou J, Chen C, Qu Y, Wang J, Lu F, Liu Y, Cai J, Ji S, Li Y, Gu H, Zhao F, Lyu Y, Shi X. Vitamin B12 is associated negatively with anemia in older Chinese adults with a low dietary diversity level: evidence from the Healthy Ageing and Biomarkers Cohort Study (HABCS). BMC Geriatrics 2024, 24: 18. PMID: 38178043, PMCID: PMC10768404, DOI: 10.1186/s12877-023-04586-7.Peer-Reviewed Original ResearchConceptsVitamin B12 levelsDietary diversity scorePlasma vitamin B12 levelsB12 levelsFood frequency questionnaireDifferent dietary patternsOlder adultsFrequency questionnaireDietary patternsHigh vitamin B12 levelsVitamin B12Low dietary diversity scoreHigh dietary diversity scorePrevalence of anemiaElderly Chinese peopleBiomarker cohort studyOlder Chinese adultsCohort studyAnemia statusDecreased riskMean ageAnemiaChinese adultsConclusionThe relationshipConfounding factorsAssociation of Thallium Exposure with Decreased Renal Function among Chinese Adults — China, 2017–2018
Zhang Z, Zhang M, Qu Y, Zhao F, Ji S, Li Z, Wu B, Lyu C, Song H, Sun Q, Li Y, Zhang X, Zheng X, Qiu Y, Lu Z, Fu H, Xu L, Zhang W, Luo Y, Li F, Cai J, Zhu Y, Zhu Y, Cao Z, Lyu Y, Shi X. Association of Thallium Exposure with Decreased Renal Function among Chinese Adults — China, 2017–2018. China CDC Weekly 2024, 6: 867-871. PMID: 39211414, PMCID: PMC11350231, DOI: 10.46234/ccdcw2024.186.Peer-Reviewed Original Research