Associations of Serum Per- and Polyfluoroalkyl Substances with Hyperuricemia in Adults: A Nationwide Cross-Sectional Study
Zheng X, Pan Y, Qu Y, Ji S, Wang J, Li Z, Zhao F, Wu B, Xie L, Li Y, Song H, Hu X, Qiu Y, Zhang Z, Zhang W, Yang Y, Cai J, Zhu Y, Zhu Y, Cao Z, Ji J, Lv Y, Dai J, Shi X. Associations of Serum Per- and Polyfluoroalkyl Substances with Hyperuricemia in Adults: A Nationwide Cross-Sectional Study. Environmental Science And Technology 2024, 58: 12875-12887. PMID: 38980177, DOI: 10.1021/acs.est.3c11095.Peer-Reviewed Original ResearchNationwide cross-sectional studyPublic health planningCross-sectional studyOdds of hyperuricemiaChinese adultsHealth plansJoint effectsElevated oddsGeneral populationNationwide studyNonmonotonic dose responsePositive associationRisk factorsAdultsHealthEffects of polyfluoroalkyl substancesHealth hazardsParticipantsSerum polyfluoroalkyl substancesJoint effects of PFAS mixtureMeasured serum concentrationsFish consumptionSerum concentrations of uric acidAssociationHyperuricemiaPositive Associations of Perfluoroalkyl and Polyfluoroalkyl Substances With Hypertension May Be Attenuated by Endogenous Sex Hormones: A Nationally Representative Cross-Sectional Study
Wu B, Sheng N, Li Z, Wang J, Ji S, Zhao F, Pan Y, Qu Y, Wei Y, Xie L, Li Y, Hu X, Wu C, Zhang Z, Qiu Y, Zheng X, Zhang W, Hu X, Song H, Cai J, Cao Z, Ji J, Lv Y, Dai J, Shi X. Positive Associations of Perfluoroalkyl and Polyfluoroalkyl Substances With Hypertension May Be Attenuated by Endogenous Sex Hormones: A Nationally Representative Cross-Sectional Study. Hypertension 2024, 81: 1799-1810. PMID: 38853753, DOI: 10.1161/hypertensionaha.123.22127.Peer-Reviewed Original ResearchDiastolic blood pressureSystolic blood pressureEndogenous sex hormonesBlood pressureNationally representative cross-sectional studyPositive associationPerfluoroheptane sulfonic acidWeighted multiple logistic regressionSex hormonesLevels of endogenous sex hormonesPrevalence of hypertensionCross-sectional studyMultiple logistic regressionAssociations of polyfluoroalkyl substancesPFAS mixtureJoint effects of PFAS mixtureAssociated with hypertensionProgression of hypertensionChinese adultsSynergy indexOdds ratioG-computationQuantile-based g-computationRisk ratioLogistic regression