Medical Therapy and Prognosis in Chronic Heart Failure Lessons from Clinical Trials
Ramahi T, Lee F. Medical Therapy and Prognosis in Chronic Heart Failure Lessons from Clinical Trials. Cardiology Clinics 1995, 13: 5-26. PMID: 7796432, DOI: 10.1016/s0733-8651(18)30058-4.Peer-Reviewed Original ResearchConceptsChronic heart failureLeft ventricular dysfunctionIntermediate-term improvementVentricular dysfunctionClinical trialsHeart failureLong-term improvementHemodynamic improvementLong-term effectsFunctional capacityShort-term hemodynamic improvementSystolic left ventricular dysfunctionChronic left ventricular dysfunctionACE inhibitor therapyRole of diureticsImmediate symptomatic reliefMajor clinical trialsSympathetic nervous systemMarker of prognosisGoal of therapyPure vasodilationAldosterone systemDirect vasodilatorAcute stabilizationPharmacologic therapy