2009
How form follows functional genomics: gene expression profiling gastric epithelial cells with a particular discourse on the parietal cell
Capoccia BJ, Huh WJ, Mills JC. How form follows functional genomics: gene expression profiling gastric epithelial cells with a particular discourse on the parietal cell. Physiological Genomics 2009, 37: 67-78. PMID: 19208773, PMCID: PMC2685495, DOI: 10.1152/physiolgenomics.90408.2008.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsFunctional genomic studiesFunctional genomicsGene expressionGenomic studiesCell lineagesEntire cellular transcriptomeGene ontology analysisDifferentiated cell lineagesGene expression patternsCellular transcriptomeParietal cellsVascular endothelial growth factor BIndividual genesLineage-specific markersOntology analysisCell physiologyGene productsMolecular anatomyGastric parietal cellsExpression patternsMicroarray analysisMolecular mechanismsCell-specific markersGastric epithelial cellsGrowth factor B
2008
The gastric epithelial progenitor cell niche and differentiation of the zymogenic (chief) cell lineage
Bredemeyer AJ, Geahlen JH, Weis VG, Huh WJ, Zinselmeyer BH, Srivatsan S, Miller MJ, Shaw AS, Mills JC. The gastric epithelial progenitor cell niche and differentiation of the zymogenic (chief) cell lineage. Developmental Biology 2008, 325: 211-224. PMID: 19013146, PMCID: PMC2634829, DOI: 10.1016/j.ydbio.2008.10.025.Peer-Reviewed Original ResearchMeSH KeywordsAdaptor Proteins, Signal TransducingAnimalsBasic Helix-Loop-Helix Transcription FactorsCadherinsCell DifferentiationCell LineageCell PolarityCell ProliferationChief Cells, GastricCytoskeletal ProteinsEpithelial CellsIntercellular JunctionsMiceModels, BiologicalParietal Cells, GastricProtein BindingProtein TransportStem Cell NicheStem CellsConceptsZymogenic cellsProgenitor nicheCell fate decisionsE-cadherin localizationZymogenic cell lineagesMammalian gastrointestinal tractProgenitor cell nicheParietal cellsLineage progenitor cellsKey cellular componentsFate decisionsDiverse lineagesProgenitor stateDifferentiated cell markersCell nicheGastric parietal cellsCell lineagesPremature expressionCellular componentsGastric unitsLineagesNicheGenetic ablationLineage cellsProgenitor cells