2020
Identifying a Kidney Transplant Recipient COVID Phenotype to Aid Test Utilization in the Setting of Limited Testing Availability—Does One Exist?
Virmani S, Gleeson SE, Girone GF, Malhotra D, Cohen EA, Klarman SE, Asch WS. Identifying a Kidney Transplant Recipient COVID Phenotype to Aid Test Utilization in the Setting of Limited Testing Availability—Does One Exist? Transplantation Proceedings 2020, 52: 2584-2591. PMID: 32711848, PMCID: PMC7305913, DOI: 10.1016/j.transproceed.2020.05.033.Peer-Reviewed Original ResearchConceptsKidney transplant recipientsSARS-CoV-2BK viremiaLimited testing availabilityTesting availabilitySevere acute respiratory syndrome 2 virusImmunosuppressed kidney transplant recipientsOutpatient testing centerPolyoma BK viremiaCOVID-19 infectionPositive predictive valueTransplant recipientsImmunocompetent patientsSymptomatic patientsImmunosuppressed patientsTransplant centersHigh morbidityEmergency departmentInpatient treatmentGeneral populationHigh incidencePatientsCenter deliveriesPredictive valueTest utilization
2017
Delayed Graft Function Phenotypes and 12-Month Kidney Transplant Outcomes
Hall IE, Reese PP, Doshi MD, Weng FL, Schröppel B, Asch WS, Ficek J, Thiessen-Philbrook H, Parikh CR. Delayed Graft Function Phenotypes and 12-Month Kidney Transplant Outcomes. Transplantation 2017, 101: 1913-1923. PMID: 27495761, PMCID: PMC5292094, DOI: 10.1097/tp.0000000000001409.Peer-Reviewed Original ResearchConceptsIschemia-reperfusion injurySlow graft functionDelayed graft functionKidney transplant outcomesGraft functionTransplant outcomesCreatinine reductionDeath-censored graft failureDeceased donor kidney recipientsPoor kidney transplant outcomesSevere ischemia-reperfusion injuryGlomerular filtration rateLong-term outcomesLarger translational studiesDGF definitionsIRI severityKidney recipientsDialysis initiationGraft failureProspective studyUnited NetworkFiltration rateRelative riskDialysis sessionOrgan Sharing
2000
Plasticin, a Type III Neuronal Intermediate Filament Protein, Assembles as an Obligate Heteropolymer
Asch WS, Schechter N. Plasticin, a Type III Neuronal Intermediate Filament Protein, Assembles as an Obligate Heteropolymer. Journal Of Neurochemistry 2000, 75: 1475-1486. PMID: 10987827, DOI: 10.1046/j.1471-4159.2000.0751475.x.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SubstitutionAnimalsAxonsBiopolymersCatalysisCell LineEpidermolysis Bullosa SimplexEye ProteinsHemagglutininsHumansImmunohistochemistryIntermediate Filament ProteinsIntermediate FilamentsMutagenesis, Site-DirectedNerve Tissue ProteinsNeuronsPhenotypeRecombinant Fusion ProteinsTemperatureTransfectionVimentinZebrafishConceptsIntermediate filament proteinsEpidermolysis bullosa simplexPoint mutationsMammalian intermediate filament proteinsFilament proteinsCytoplasmic filament networkNeuronal intermediate filament proteinWeight NF proteinsTermination sequenceSW13 cellsObligate heteropolymersStructural differencesFilament networkCoil regionFilament aggregationKeratin mutationsMutationsImportant structural differencesAssembly propertiesProteinNF proteinsFirst heptadNumber of aggregatesPlasticinGrowth characteristics