2023
Maternal FGF2 levels associated with child anxiety and depression symptoms through child FGF2 levels
Lebowitz E, Marin C, Orbach M, Salmaso N, Vaccarino F, Silverman W. Maternal FGF2 levels associated with child anxiety and depression symptoms through child FGF2 levels. Journal Of Affective Disorders 2023, 326: 193-197. PMID: 36717031, PMCID: PMC10104478, DOI: 10.1016/j.jad.2023.01.090.Peer-Reviewed Original ResearchConceptsFGF2 levelsDepressive symptomsDepression symptomsChild anxietySymptoms of anxietyRatings of anxietyGrowth factor 2Maternal anxietySymptomsDepressed childrenDepressionChild depressionMothersChildrenFactor 2Self-report ratingsAnxietyIntergenerational pathwaysNon-referred childrenRange of anxietyFGF2AssociationLevelsMaternal
2022
Age and depressive symptoms change predict the 4‐year self‐concept trajectory for youth after anxiety treatment
Fjermestad KW, Bellika K, Matre C, Silverman WK, Wergeland GJ. Age and depressive symptoms change predict the 4‐year self‐concept trajectory for youth after anxiety treatment. Journal Of Clinical Psychology 2022, 78: 2109-2121. PMID: 35975330, PMCID: PMC9804830, DOI: 10.1002/jclp.23427.Peer-Reviewed Original ResearchSociodemographic and clinical characteristics of youths and parents seeking psychological treatment for school attendance problems
Johnsen DB, Lomholt JJ, Heyne D, Jeppesen P, Jensen MB, Silverman WK, Thastum M. Sociodemographic and clinical characteristics of youths and parents seeking psychological treatment for school attendance problems. PLOS ONE 2022, 17: e0261449. PMID: 35081106, PMCID: PMC8791456, DOI: 10.1371/journal.pone.0261449.Peer-Reviewed Original ResearchConceptsMental health problemsSchool attendance problemsPsychological treatmentHelp-seeking youthHealth problemsAttendance problemsClinical characteristicsBehavioral difficultiesCross-sectional designNegative outcomesOlder youthYouthEarly interventionClinical levelParentsTreatment startBaseline assessmentSchool absenceSociodemographic characteristicsTreatmentAnxietyHigh levelsLow levelsDepressionAbsenceShort report: COVID-19-related anxiety is associated with mental health problems among adults with rare disorders
Fjermestad KW, Orm S, Silverman WK, Cogo-Moreira H. Short report: COVID-19-related anxiety is associated with mental health problems among adults with rare disorders. Research In Developmental Disabilities 2022, 123: 104181. PMID: 35114595, PMCID: PMC8789552, DOI: 10.1016/j.ridd.2022.104181.Peer-Reviewed Original Research
2021
Effectiveness of Transdiagnostic Cognitive-Behavioral Psychotherapy Compared With Management as Usual for Youth With Common Mental Health Problems
Jeppesen P, Wolf RT, Nielsen SM, Christensen R, Plessen KJ, Bilenberg N, Thomsen PH, Thastum M, Neumer SP, Puggaard LB, Pedersen M, Pagsberg AK, Silverman WK, Correll CU. Effectiveness of Transdiagnostic Cognitive-Behavioral Psychotherapy Compared With Management as Usual for Youth With Common Mental Health Problems. JAMA Psychiatry 2021, 78: 250-260. PMID: 33355633, PMCID: PMC7758821, DOI: 10.1001/jamapsychiatry.2020.4045.Peer-Reviewed Original ResearchConceptsMental health problemsCommon mental health problemsHealth problemsMAU groupSecondary outcomesWeek 26Clinical trialsWeek 18Depressive symptomsPrimary outcome dataMain inclusion criteriaNumber of respondersMental health careBehavioral problemsHelp-seeking youthCognitive behavioral therapy programParent-reported changesTreat populationUsual carePrimary outcomeManualized CBTCognitive-behavioral psychotherapyInclusion criteriaMAIN OUTCOMEBehavioral disturbancesFibroblast Growth Factor 2 Implicated in Childhood Anxiety and Depression Symptoms
Lebowitz ER, Orbach M, Marin CE, Salmaso N, Vaccarino FM, Silverman WK. Fibroblast Growth Factor 2 Implicated in Childhood Anxiety and Depression Symptoms. Journal Of Affective Disorders 2021, 282: 611-616. PMID: 33445083, PMCID: PMC7897422, DOI: 10.1016/j.jad.2020.12.055.Peer-Reviewed Original ResearchMaternal Depression and Mother-Child Oxytocin Synchrony in Youth with Anxiety Disorders
Gadassi Polack R, Joormann J, Orbach M, Silverman WK, Lebowitz ER. Maternal Depression and Mother-Child Oxytocin Synchrony in Youth with Anxiety Disorders. Research On Child And Adolescent Psychopathology 2021, 49: 381-392. PMID: 33403493, DOI: 10.1007/s10802-020-00744-2.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnxiety DisordersChildDepressionFemaleHumansMother-Child RelationsMothersOxytocinConceptsMaternal depressionAnxiety disordersDepressive symptomsOT levelsBehavior problemsOwn depressive symptomsChild internalizing symptomsChild behavior problemsMother-child dyadsPsychiatric evaluationHigh levelsPeripheral measuresNegative affectChild anxietyNeuropeptide oxytocinInternalizing symptomsPhysiological synchronyBehavioral synchronySymptomsBehavioral codingInteraction tasksSalivary oxytocinAffiliative bondsDisordersDepression
2018
Negative peer social interactions and oxytocin levels linked to suicidal ideation in anxious youth
Lebowitz ER, Blumberg HP, Silverman WK. Negative peer social interactions and oxytocin levels linked to suicidal ideation in anxious youth. Journal Of Affective Disorders 2018, 245: 806-811. PMID: 30699863, PMCID: PMC6361537, DOI: 10.1016/j.jad.2018.11.070.Peer-Reviewed Original ResearchConceptsNegative peer interactionsPeer social interactionSalivary oxytocin levelsAnxious youthPeer interactionsHigher oxytocin levelsAnxiety disordersOxytocin levelsSocial interactionSuicidal ideationSocial eventsSelf-report measuresPrimary anxiety disorderSemi-structured diagnostic interviewNegative social interactionsPeripheral oxytocin levelsSample of childrenPeer victimizationDevelopmental Window of Opportunity: Implications of Parent-Child Psychotherapy for Early Childhood Depression Treatment
Silverman WK, Pettit JW. Developmental Window of Opportunity: Implications of Parent-Child Psychotherapy for Early Childhood Depression Treatment. American Journal Of Psychiatry 2018, 175: 1051-1053. PMID: 30380932, DOI: 10.1176/appi.ajp.2018.18060733.Peer-Reviewed Original Research
2012
Race and Perceived Pubertal Transition Effects on Girls’ Depressive Symptoms and Delinquent Behaviors
Carter R, Silverman WK, Jaccard J. Race and Perceived Pubertal Transition Effects on Girls’ Depressive Symptoms and Delinquent Behaviors. Journal Of Youth And Adolescence 2012, 42: 1155-1168. PMID: 23275063, DOI: 10.1007/s10964-012-9885-1.Peer-Reviewed Original Research
2008
Pubertal timing and its link to behavioral and emotional problems among ‘at‐risk’ African American adolescent girls
Carter R, Jaccard J, Silverman WK, Pina AA. Pubertal timing and its link to behavioral and emotional problems among ‘at‐risk’ African American adolescent girls. Journal Of Adolescence 2008, 32: 467-481. PMID: 18801563, PMCID: PMC2796368, DOI: 10.1016/j.adolescence.2008.07.005.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAdolescentAge FactorsAnxietyBehavioral SymptomsBlack or African AmericanChildDepressionEmotionsFemaleFloridaHumansInternal-External ControlJuvenile DelinquencyParentsPubertyRetrospective StudiesRisk FactorsSchoolsSex FactorsSubstance-Related DisordersSurveys and QuestionnairesConceptsRetrospective reportsPubertal timingEmotional problemsTeacher reportsStructural equation modeling resultsAfrican American adolescent girlsAdolescent internalizing problemsAmerican adolescent girlsGirls' pubertal developmentAfrican American girlsPsychosocial adjustmentInternalizing problemsDelinquent behaviorBehavioral problemsPubertal developmentRelative pubertal timingAdolescent girlsAmerican girlsGirlsStudy findingsDisadvantaged urban settingTeachersPresent studyPeersFindingsMeasures matter: the relative contribution of anxiety and depression to suicidal ideation in clinically referred anxious youth using brief versus full length questionnaires
Carter R, Silverman WK, Allen A, Ham L. Measures matter: the relative contribution of anxiety and depression to suicidal ideation in clinically referred anxious youth using brief versus full length questionnaires. Depression And Anxiety 2008, 25: e27-e35. PMID: 18729149, DOI: 10.1002/da.20468.Peer-Reviewed Original ResearchConceptsManifest Anxiety ScaleAnxious youthChildren's Manifest Anxiety ScaleDepression InventoryIndirect effectsChildren's Depression InventoryStructural equation modelingSignificant direct effectSuicidal ideationChildhood anxietyLength versionCross-sectional designAnxiety ScaleFull-length questionnairesBrief versionEquation modelingAnxietyMeasurement strategyIdeationDepressionFull-length versionYouthDifferent findingsRelative contributionRCMAS
2001
Anxiety sensitivity, anxiety, and depression in older patients and their relation to hypochondriacal concerns and medical illnesses
Bravo IM, Silverman WK. Anxiety sensitivity, anxiety, and depression in older patients and their relation to hypochondriacal concerns and medical illnesses. Aging & Mental Health 2001, 5: 349-357. PMID: 11767983, DOI: 10.1080/13607860120080305.Peer-Reviewed Original ResearchMeSH KeywordsAgedAnxietyAttitude to HealthDepressionFemaleHumansHypochondriasisMaleSurveys and Questionnaires