2019
Efficacy and mechanisms underlying a gamified attention bias modification training in anxious youth: protocol for a randomized controlled trial
Linke JO, Jones E, Pagliaccio D, Swetlitz C, Lewis KM, Silverman WK, Bar-Haim Y, Pine DS, Brotman MA. Efficacy and mechanisms underlying a gamified attention bias modification training in anxious youth: protocol for a randomized controlled trial. BMC Psychiatry 2019, 19: 246. PMID: 31391027, PMCID: PMC6686536, DOI: 10.1186/s12888-019-2224-2.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyContext of CBTBias modification trainingDot-probe taskAttentional biasAnxious youthAmygdala connectivityAnxiety disordersAttention bias modification trainingPrimary anxiety disorder diagnosisHealthy comparison youthAnxiety disorder diagnosisVisual searchThreat responsesNeurobiological correlatesComparison youthBehavioral therapyTraining elementsDisorder diagnosisEngaging gameNeuronal levelYouthPrevious findingsMixed resultsTask
2016
Non-replication of the association between 5HTTLPR and response to psychological therapy for child anxiety disorders
Lester KJ, Roberts S, Keers R, Coleman JR, Breen G, Wong CC, Xu X, Arendt K, Blatter-Meunier J, Bögels S, Cooper P, Creswell C, Heiervang ER, Herren C, Hogendoorn SM, Hudson JL, Krause K, Lyneham HJ, McKinnon A, Morris T, Nauta MH, Rapee RM, Rey Y, Schneider S, Schneider SC, Silverman WK, Smith P, Thastum M, Thirlwall K, Waite P, Wergeland GJ, Eley TC. Non-replication of the association between 5HTTLPR and response to psychological therapy for child anxiety disorders. The British Journal Of Psychiatry 2016, 208: 182-188. PMID: 26294368, PMCID: PMC4837384, DOI: 10.1192/bjp.bp.114.154997.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyCBT outcomeChild anxietyAnxiety disordersChild anxiety disordersMore positive outcomesShort-allele homozygotesPositive treatment outcomesPsychological therapiesDisorder outcomesPositive outcomesTreatment studiesHomogenous sampleMixed resultsAnxietyMixed effects modelsNon-significant effectTreatment outcomesCohort 2DisordersSignificant associationFuture studiesOutcomesAssociationTherapy