2010
What Is the Future of Stroke Prevention?
Kernan WN, Launer LJ, Goldstein LB. What Is the Future of Stroke Prevention? Stroke 2010, 41: s35-s38. PMID: 20876501, PMCID: PMC4795938, DOI: 10.1161/strokeaha.110.592022.Peer-Reviewed Original ResearchConceptsRisk factorsPolypill approachDrug-related side effectsCardiovascular risk factorsFirst ischemic strokeStroke risk factorsMultiple risk factorsOlder adult populationStroke preventionIschemic strokeBlood pressureCholesterol levelsClinical trialsSide effectsAdult populationPolypillStrokeEntire populationRiskLarge populationPopulationCertain ageMedicationsPharmacodynamicsPharmacokinetics
2005
Altruism as a reason for participation in clinical trials was independently associated with adherence
Rosenbaum JR, Wells CK, Viscoli CM, Brass LM, Kernan WN, Horwitz RI. Altruism as a reason for participation in clinical trials was independently associated with adherence. Journal Of Clinical Epidemiology 2005, 58: 1109-1114. PMID: 16223653, DOI: 10.1016/j.jclinepi.2005.03.014.Peer-Reviewed Original ResearchConceptsClinical trialsBetter functional statusStudy medicationMedical regimenRecruitment of participantsClinical featuresStroke trialsFunctional statusWomen's EstrogenStratified analysisMultivariable regressionClinical researchEstrogenTrialsAdherenceBaseline featuresSocial supportFurther investigationWomenParticipantsAltruistic reasonsPossible contributionHigh levelsPlaceboMedications