Featured Publications
Diagnosis of ventilator-associated pneumonia in critically ill adult patients—a systematic review and meta-analysis
Fernando SM, Tran A, Cheng W, Klompas M, Kyeremanteng K, Mehta S, English SW, Muscedere J, Cook DJ, Torres A, Ranzani OT, Fox-Robichaud AE, Alhazzani W, Munshi L, Guyatt GH, Rochwerg B. Diagnosis of ventilator-associated pneumonia in critically ill adult patients—a systematic review and meta-analysis. Intensive Care Medicine 2020, 46: 1170-1179. PMID: 32306086, PMCID: PMC7223448, DOI: 10.1007/s00134-020-06036-z.Peer-Reviewed Original ResearchConceptsVentilator-associated pneumoniaEndotracheal aspiratesChest radiographyDiagnosis of VAPBronchoscopic sampling methodsIll adult patientsPhysical examination findingsEnglish-language studiesUnnecessary antimicrobial useAdult patientsVAP diagnosisPurulent secretionsExamination findingsPhysical examinationClinical indicatorsAntibiotic treatmentHistopathological analysisStudy qualitySystematic reviewAntimicrobial usePooled sensitivityDiagnosisPneumoniaReference standardRadiography
2018
Prognostic Accuracy of the Quick Sequential Organ Failure Assessment for Mortality in Patients With Suspected Infection: A Systematic Review and Meta-analysis.
Fernando SM, Tran A, Taljaard M, Cheng W, Rochwerg B, Seely AJE, Perry JJ. Prognostic Accuracy of the Quick Sequential Organ Failure Assessment for Mortality in Patients With Suspected Infection: A Systematic Review and Meta-analysis. Annals Of Internal Medicine 2018, 168: 266-275. PMID: 29404582, DOI: 10.7326/m17-2820.Peer-Reviewed Original ResearchConceptsQuick Sequential Organ Failure AssessmentPrediction of mortalitySequential Organ Failure AssessmentOrgan Failure AssessmentIntensive care unitNon-ICU populationSIRS criteriaICU populationAdult patientsPooled specificityEmergency departmentPooled sensitivityPrognostic accuracySystemic inflammatory response syndrome criteriaShort-term mortalityScreening of patientsFailure AssessmentEnglish-language studiesSyndrome criteriaTreatment initiationCare unitPatient selectionStudy qualityEmergency physiciansHospital wards