2000
Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice
Bibb J, Yan Z, Svenningsson P, Snyder G, Pieribone V, Horiuchi A, Nairn A, Messer A, Greengard P. Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice. Proceedings Of The National Academy Of Sciences Of The United States Of America 2000, 97: 6809-6814. PMID: 10829080, PMCID: PMC18747, DOI: 10.1073/pnas.120166397.Peer-Reviewed Original ResearchConceptsMedium spiny neuronsDisease miceSpiny neuronsStriatal medium spiny neuronsHuntington's diseaseSevere deficiencyHuntington's disease miceHD model miceModel miceDopaminergic neurotransmissionHD miceSelective neurodegenerationHD pathologyMiceDARPP-32DopamineHuman huntingtinBehavioral phenotypesDiseaseNeuronsIon channelsTotal levelsDisease-causing formHuntingtinDeficiency
1993
CGRP-like immunoreactivity in A11 dopamine neurons projecting to the spinal cord and a note on CGRP-CCK cross-reactivity
Orazzo C, Pieribone V, Ceccatelli S, Terenius L, Hökfelt T. CGRP-like immunoreactivity in A11 dopamine neurons projecting to the spinal cord and a note on CGRP-CCK cross-reactivity. Brain Research 1993, 600: 39-48. PMID: 8422589, DOI: 10.1016/0006-8993(93)90399-8.Peer-Reviewed Original ResearchConceptsCGRP antiserumSpinal cordRat brainCalcitonin gene-related peptideDopamine cell groupsCGRP-like immunoreactivityGene-related peptideIndirect immunofluorescence techniqueLike immunoreactivityDopamine neuronsBrain areasDouble-labeling procedureImmunofluorescence techniqueCell groupsCholecystokininCatecholamine groupsCordImmunohistochemistryImmunoreactivityNeuronsRadioimmunoassayBrainPresent studyTerminal portionAntiserum