2022
Voltage imaging in the olfactory bulb using transgenic mouse lines expressing the genetically encoded voltage indicator ArcLight
Platisa J, Zeng H, Madisen L, Cohen LB, Pieribone VA, Storace DA. Voltage imaging in the olfactory bulb using transgenic mouse lines expressing the genetically encoded voltage indicator ArcLight. Scientific Reports 2022, 12: 1875. PMID: 35115567, PMCID: PMC8813909, DOI: 10.1038/s41598-021-04482-3.Peer-Reviewed Original ResearchConceptsTransgenic mouse lineMouse linesOlfactory bulbSubpopulation of interneuronsVivo mammalian brainTransgenic reporter animalsTransgenic reporter miceOlfactory receptor neuronsNeuronal electrical activityVoltage indicator ArcLightGlomerular layerReporter miceMammalian brainReceptor neuronsReporter animalsHigh expression levelsElectrical activityMembrane potential changesOdorant responsesNeural activityCell populationsSingle trialExpression levelsVivo experimentsDifferent cell types
2018
Genetically encoded fluorescent voltage indicators: are we there yet?
Platisa J, Pieribone VA. Genetically encoded fluorescent voltage indicators: are we there yet? Current Opinion In Neurobiology 2018, 50: 146-153. PMID: 29501950, PMCID: PMC5984684, DOI: 10.1016/j.conb.2018.02.006.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrainFluorescence Resonance Energy TransferHumansLuminescent ProteinsVoltage-Sensitive Dye ImagingConceptsNeuronal activity
2017
Directed Evolution of Key Residues in Fluorescent Protein Inverses the Polarity of Voltage Sensitivity in the Genetically Encoded Indicator ArcLight
Platisa J, Vasan G, Yang A, Pieribone VA. Directed Evolution of Key Residues in Fluorescent Protein Inverses the Polarity of Voltage Sensitivity in the Genetically Encoded Indicator ArcLight. ACS Chemical Neuroscience 2017, 8: 513-523. PMID: 28045247, PMCID: PMC5355904, DOI: 10.1021/acschemneuro.6b00234.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCells, CulturedCerebral CortexElectric StimulationEmbryo, MammalianGreen Fluorescent ProteinsHEK293 CellsHumansLuminescent ProteinsMiceModels, MolecularMolecular BiologyMutagenesis, Site-DirectedMutationNeuronsPatch-Clamp TechniquesRecombinant Fusion ProteinsTransfectionVoltage-Sensitive Dye Imaging
2012
Single Action Potentials and Subthreshold Electrical Events Imaged in Neurons with a Fluorescent Protein Voltage Probe
Jin L, Han Z, Platisa J, Wooltorton JR, Cohen LB, Pieribone VA. Single Action Potentials and Subthreshold Electrical Events Imaged in Neurons with a Fluorescent Protein Voltage Probe. Neuron 2012, 75: 779-785. PMID: 22958819, PMCID: PMC3439164, DOI: 10.1016/j.neuron.2012.06.040.Peer-Reviewed Original Research
2011
Effect of high velocity, large amplitude stimuli on the spread of depolarization in S1 “barrel” cortex
Davis DJ, Sachdev R, Pieribone VA. Effect of high velocity, large amplitude stimuli on the spread of depolarization in S1 “barrel” cortex. Somatosensory & Motor Research 2011, 28: 73-85. PMID: 22150170, PMCID: PMC3753103, DOI: 10.3109/08990220.2011.613177.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsMaleMiceNeuronsPhysical StimulationSomatosensory CortexVibrissaeVoltage-Sensitive Dye Imaging