1995
Distinct pools of synaptic vesicles in neurotransmitter release
Pieribone V, Shupliakov O, Brodin L, Hilfiker-Rothenfluh S, Czernik A, Greengard P. Distinct pools of synaptic vesicles in neurotransmitter release. Nature 1995, 375: 493-497. PMID: 7777058, DOI: 10.1038/375493a0.Peer-Reviewed Original ResearchConceptsNeurotransmitter releaseCellular secretory systemSynaptic vesiclesLow-frequency stimulationSynaptic release sitesRelease of neurotransmittersHigh-frequency burstsNeuron-specific proteinSynapsin antibodiesPool of vesiclesDistal poolNerve terminalsMarked depressionVesicular releasePresynaptic membraneSynapsinHigh rateClusters of vesiclesApparent effectReleaseSecretory systemSuch protein familiesNeurotransmittersRelease sites
1993
Evolutionary conservation of synaptosome-associated protein 25 kDa (SNAP-25) shown by Drosophila and Torpedo cDNA clones.
Risinger C, Blomqvist AG, Lundell I, Lambertsson A, Nässel D, Pieribone VA, Brodin L, Larhammar D. Evolutionary conservation of synaptosome-associated protein 25 kDa (SNAP-25) shown by Drosophila and Torpedo cDNA clones. Journal Of Biological Chemistry 1993, 268: 24408-24414. PMID: 8226991, DOI: 10.1016/s0021-9258(20)80540-7.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBase SequenceBiological EvolutionBlotting, NorthernConserved SequenceDNA, ComplementaryDrosophila melanogasterDrosophila ProteinsIn Situ HybridizationMembrane ProteinsMolecular Sequence DataNerve Tissue ProteinsSequence Homology, Amino AcidSynaptosomal-Associated Protein 25TorpedoConceptsVesicle dockingCDNA clonesMembrane fusionSNAP-25Basic molecular machineryDisplay sequence similarityMembrane-spanning regionSynaptic vesicle dockingDegree of conservationAmino acid identityRay Torpedo marmorataEvolutionary conservationTorpedo proteinDrosophila melanogasterMolecular machinerySequence similarityMembrane attachmentAcid identityNeuron-specific proteinCysteine residuesDrosophilaSynaptobrevinProtein 25Situ hybridizationProtein