1990
Anatomical evidence for multiple pathways leading from the rostral ventrolateral medulla (nucleus paragigantocellularis) to the locus coeruleus in rat
Astier B, Van Bockstaele E, Aston-Jones G, Pieribone V. Anatomical evidence for multiple pathways leading from the rostral ventrolateral medulla (nucleus paragigantocellularis) to the locus coeruleus in rat. Neuroscience Letters 1990, 118: 141-146. PMID: 2274260, DOI: 10.1016/0304-3940(90)90612-d.Peer-Reviewed Original ResearchConceptsRostral ventrolateral medullaLocus coeruleusPhenylethanolamine N-methyltransferaseVentrolateral medullaFluoro-GoldNucleus locus coeruleusNon-lesioned animalsNeurons persistC1 neuronsAfferent neuronsAdrenergic inputSuch lesionsLesionsAnatomical evidenceRatsRetrograde transportCoeruleusMedullaNeuronsMultiple pathways
1988
Adrenergic and non-adrenergic neurons in the C1 and C3 areas project to locus coeruleus: A fluorescent double labeling study
Pieribone V, Aston-Jones G, Bohn M. Adrenergic and non-adrenergic neurons in the C1 and C3 areas project to locus coeruleus: A fluorescent double labeling study. Neuroscience Letters 1988, 85: 297-303. PMID: 3362420, DOI: 10.1016/0304-3940(88)90582-4.Peer-Reviewed Original ResearchConceptsLocus coeruleusAfferent neuronsAdrenergic neuronsFluorescent double-labeling studyRetrograde tracer Fluoro-GoldNon-adrenergic neuronsC1 adrenergic neuronsTracer Fluoro-GoldRat locus coeruleusDouble-labeling studiesPhenylethanolamine N-methyltransferaseVentrolateral medullaDorsomedial medullaFluoro-GoldIontophoretic injectionNeuronsSubsequent immunofluorescenceCoeruleusMedullaAreas project
1986
The Brain Nucleus Locus Coeruleus: Restricted Afferent Control of a Broad Efferent Network
Aston-Jones G, Ennis M, Pieribone V, Nickell W, Shipley M. The Brain Nucleus Locus Coeruleus: Restricted Afferent Control of a Broad Efferent Network. Science 1986, 234: 734-737. PMID: 3775363, DOI: 10.1126/science.3775363.Peer-Reviewed Original ResearchConceptsLocus coeruleusWheat germ agglutinin conjugated horseradish peroxidaseParaventricular hypothalamic nucleusNucleus locus coeruleusConjugated horseradish peroxidaseMinor afferentsAfferent neuronsRetrograde labelingHypothalamic nucleiIntermediate grayElectrophysiologic experimentsFocal injectionsPrepositus hypoglossiRostral medullaDorsal capAfferent controlBrain nucleiCoeruleusEfferent networkBrain regionsAnatomic organizationAbsence of inputParagigantocellularisAfferentsHypoglossi