2024
Associations of alcohol and tobacco use with psychotic, depressive and developmental disorders revealed via multimodal neuroimaging
Qiu L, Liang C, Kochunov P, Hutchison K, Sui J, Jiang R, Zhi D, Vergara V, Yang X, Zhang D, Fu Z, Bustillo J, Qi S, Calhoun V. Associations of alcohol and tobacco use with psychotic, depressive and developmental disorders revealed via multimodal neuroimaging. Translational Psychiatry 2024, 14: 326. PMID: 39112461, PMCID: PMC11306356, DOI: 10.1038/s41398-024-03035-2.Peer-Reviewed Original ResearchConceptsFronto-limbic networkSalience networkAssociated with cognitionFronto-basal gangliaDevelopmental disordersBrain networksLimbic systemAlcohol useAssociated with alcohol useMultimodal brain networksTobacco useAssociation of alcoholPsychiatric disordersMultimodal neuroimagingDMNBrain featuresCognitionAlcohol/tobacco useDisordersAssociated with tobacco useDepressionSymptomsFunctional abnormalitiesAlcoholBrainWhite-matter changes associated with a synergetic treatment for myalgic encephalomyelitis/chronic fatigue syndrome
Mohamed A, do Campo J, Del Fante P, Kwiatek R, Calhoun V, Shan Z. White-matter changes associated with a synergetic treatment for myalgic encephalomyelitis/chronic fatigue syndrome. Fatigue Biomedicine Health & Behavior 2024, ahead-of-print: 1-11. DOI: 10.1080/21641846.2024.2367921.Peer-Reviewed Original ResearchMyalgic encephalomyelitis/chronic fatigue syndromeLow-dose naltrexoneFatigue syndromeWhite-matter tractsPre-treatment baselineDebilitating chronic illnessDeficit symptomsME/CFS patientsDiffusion-weighted imaging dataReducing depressionTreating ME/CFSSymptom improvementFractional anisotropyOff-label treatmentWhite-matter changesNaltrexoneNICE guidelinesPost-treatmentSymptomsME/CFSNeuroimaging characteristicsClinical measuresChronic illnessControl groupRandomized controlled trialsCross‐cohort replicable resting‐state functional connectivity in predicting symptoms and cognition of schizophrenia
Zhao C, Jiang R, Bustillo J, Kochunov P, Turner J, Liang C, Fu Z, Zhang D, Qi S, Calhoun V. Cross‐cohort replicable resting‐state functional connectivity in predicting symptoms and cognition of schizophrenia. Human Brain Mapping 2024, 45: e26694. PMID: 38727014, PMCID: PMC11083889, DOI: 10.1002/hbm.26694.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingNegative symptomsFunctional connectivityCognitive impairmentPrediction of negative symptomsResting-state functional connectivityAssociated with reduced cognitive functionDebilitating mental illnessHealthy controlsPredicting functional connectivityEarly adulthood onsetPositive symptomsNeural underpinningsSchizophreniaCognitive functionSensorimotor networkPredicting symptomsMental illnessConnectivity patternsClinical interventionsMagnetic resonance imagingAdulthood onsetSymptomsImpairmentResonance imaging
2023
Revisiting Functional Dysconnectivity: a Review of Three Model Frameworks in Schizophrenia
Harikumar A, Solovyeva K, Misiura M, Iraji A, Plis S, Pearlson G, Turner J, Calhoun V. Revisiting Functional Dysconnectivity: a Review of Three Model Frameworks in Schizophrenia. Current Neurology And Neuroscience Reports 2023, 23: 937-946. PMID: 37999830, PMCID: PMC11126894, DOI: 10.1007/s11910-023-01325-8.Peer-Reviewed Original ResearchConceptsNetwork dysconnectivityFunctional dysconnectivityExecutive functioningState fMRI studyAttentional deficitsFMRI studyHypothesized modelSalience networkBrain networksConnectivity findingsBehavioral symptomsNeurodevelopmental modelSymptom severityDysconnectivityHypothesized mechanismsSchizophreniaDeficitsVital modelsSummaryThis paperMotor symptomsFunctioningSymptomsFindingsPurpose of ReviewOverThought