2024
A Method to Estimate Longitudinal Change Patterns in Functional Network Connectivity of the Developing Brain Relevant to Psychiatric Problems, Cognition, and Age
Saha R, Saha D, Rahaman A, Fu Z, Liu J, Calhoun V. A Method to Estimate Longitudinal Change Patterns in Functional Network Connectivity of the Developing Brain Relevant to Psychiatric Problems, Cognition, and Age. Brain Connectivity 2024, 14: 130-140. PMID: 38308475, PMCID: PMC10954605, DOI: 10.1089/brain.2023.0040.Peer-Reviewed Original ResearchFunctional network connectivityFunctional connectivityPsychiatric problemsFunctional network connectivity matricesNetwork connectivityMultivariate patternsWhole-brain functional networksIntrinsic functional connectivityPattern of functional changesBrain functional connectivityIntrinsic functional relationshipLongitudinal changesAdolescent brainAge-related changesBrain networksStudy developmental changesScanning sessionBrain functionAssociated with longitudinal changesCognitive scoresDevelopmental changesBrain developmentFunctional changesCognitionLongitudinal change patternsBetter with age: Developmental changes in oscillatory activity during verbal working memory encoding and maintenance
Killanin A, Ward T, Embury C, Calhoun V, Wang Y, Stephen J, Picci G, Heinrichs-Graham E, Wilson T. Better with age: Developmental changes in oscillatory activity during verbal working memory encoding and maintenance. Developmental Cognitive Neuroscience 2024, 66: 101354. PMID: 38330526, PMCID: PMC10864839, DOI: 10.1016/j.dcn.2024.101354.Peer-Reviewed Original ResearchWorking memory encodingMemory encodingLeft hemisphere language regionsSternberg verbal working memory taskVerbal working memory taskRight superior temporal regionOlder participantsWorking memory taskWorking memory developmentSuperior temporal regionsSignificant oscillatory responsesWhole-brain mappingDevelopmental effectsMemory taskWorking memoryOscillatory responsesLanguage regionsBrain regionsMemory developmentOscillatory dynamicsTheta powerParticipants aged 6Whole-brainTemporal regionsDevelopmental changes
2023
Developmental changes in endogenous testosterone have sexually‐dimorphic effects on spontaneous cortical dynamics
Picci G, Ott L, Penhale S, Taylor B, Johnson H, Willett M, Okelberry H, Wang Y, Calhoun V, Stephen J, Wilson T. Developmental changes in endogenous testosterone have sexually‐dimorphic effects on spontaneous cortical dynamics. Human Brain Mapping 2023, 44: 6043-6054. PMID: 37811842, PMCID: PMC10619376, DOI: 10.1002/hbm.26496.Peer-Reviewed Original ResearchConceptsCortical activityRobust sex differencesFunctional brain developmentTypically-developing youthSpontaneous cortical activityLowest relative powerCortical dynamicsEndogenous testosteronePrefrontal cortexExecutive functionFrontal cortexPubertal hormonesNeural circuitryResting-stateStructural MRIEffects of testosteroneSex differencesEffects of endogenous testosteroneDevelopmental changesBrain developmentReverse patternBehavioral changesGamma activityDevelopmental windowDevelopmental patternsTransdiagnostic indicators predict developmental changes in cognitive control resting-state networks.
Picci G, Petro N, Son J, Agcaoglu O, Eastman J, Wang Y, Stephen J, Calhoun V, Taylor B, Wilson T. Transdiagnostic indicators predict developmental changes in cognitive control resting-state networks. Development And Psychopathology 2023, 1-11. PMID: 37615120, PMCID: PMC11140239, DOI: 10.1017/s0954579423001013.Peer-Reviewed Original ResearchResting-state networksExposure to childhood traumaLatent growth curve analysisResting-state fMRI studiesResting-state functional networksWithin-network connectivityFunctional networksMental health symptomsGrowth curve analysisLevels of dysregulationCognitive controlFMRI studyChildhood traumaNeurobiological processesTraumatic exposureDevelopmental trajectoriesHealth symptomsClinical populationsLongitudinal designPredictive utilityPsychopathologyDevelopmental changesYouth riskConnectivity patternsGreater levelsTestosterone levels mediate the dynamics of motor oscillatory coding and behavior in developing youth
Killanin A, Taylor B, Embury C, Picci G, Wang Y, Calhoun V, Stephen J, Heinrichs-Graham E, Wilson T. Testosterone levels mediate the dynamics of motor oscillatory coding and behavior in developing youth. Developmental Cognitive Neuroscience 2023, 61: 101257. PMID: 37236034, PMCID: PMC10232658, DOI: 10.1016/j.dcn.2023.101257.Peer-Reviewed Original ResearchConceptsMotor performanceEffects of ageSalivary testosterone samplesMotor sequence taskMultiple mediation modelMovement-related beta activityBeta oscillatory dynamicsMeasures of motor performanceYouth aged 9Complex motor performanceLeft primary motor cortexPubertal transition periodBeta activitySequencing taskTestosterone samplesMediation modelMotor planningMotor regionsTask behaviorPrimary motor cortexDevelopmental changesBehavior indexYoung adulthoodTestosterone levelsAged 9