2016
The emerging role of microRNAs in hypoxia-induced pulmonary hypertension
Mohsenin V. The emerging role of microRNAs in hypoxia-induced pulmonary hypertension. Sleep And Breathing 2016, 20: 1059-1067. PMID: 27154628, DOI: 10.1007/s11325-016-1351-y.Peer-Reviewed Original ResearchConceptsPulmonary arterial hypertensionHypoxia-induced pulmonary hypertensionPulmonary hypertensionArterial hypertensionHeart failureRole of microRNAsMechanism of PHPulmonary arterial blood pressurePulmonary arterial smooth muscle cellsDevelopment of PHIdiopathic pulmonary arterial hypertensionChronic obstructive lung diseasePathogenesis of PHArterial smooth muscle cellsRight heart failureRight ventricular dysfunctionPoor prognostic signArterial blood pressureCongestive heart failureObstructive lung diseaseSleep-disordered breathingSetting of hypoxiaAberrant vascular remodelingQuality of lifeSmooth muscle cells
2006
Chronic obstructive pulmonary disease and sleep: the interaction.
Urbano F, Mohsenin V. Chronic obstructive pulmonary disease and sleep: the interaction. Panminerva Medica 2006, 48: 223-30. PMID: 17215794.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseObstructive pulmonary diseasePulmonary diseaseSevere chronic obstructive pulmonary diseaseRespiratory muscle fatigueRight ventricular overloadElevated pulmonary pressuresUpper airway resistanceFourth leading causeFunctional residual capacityGoal of therapyOxyhemoglobin dissociation curveProfound adverse effectsMillion adultsResultant hypoxemiaOxygen desaturationPulmonary rehabilitationPulmonary pressureVentricular overloadAirway resistanceRespiratory driveSmoking cessationMorning fatigueLung mechanicsSleep disturbances
1994
Daytime oxygen saturation does not predict nocturnal oxygen desaturation in patients with chronic obstructive pulmonary disease
Mohsenin V, Guffanti E, Hilbert J, Ferranti R. Daytime oxygen saturation does not predict nocturnal oxygen desaturation in patients with chronic obstructive pulmonary disease. Archives Of Physical Medicine And Rehabilitation 1994, 75: 285-289. PMID: 8129580, DOI: 10.1016/0003-9993(94)90030-2.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseNocturnal oxygen desaturationObstructive pulmonary diseaseOxygen desaturationAwake SaO2Nocturnal hypoxemiaPulmonary diseaseOxygen saturationDaytime oxygen saturationArterial oxygen saturationControl of breathingNocturnal SaO2COPD patientsPulmonary hypertensionAwake patientsPathologic mechanismsIndividual patientsNocturnal oximetryCardiac arrhythmiasPatientsSaO2HypoxemiaDesaturationOximetryDisease