2004
Is sleep apnea a risk factor for stroke? A critical analysis.
Mohsenin V. Is sleep apnea a risk factor for stroke? A critical analysis. Minerva Medica 2004, 95: 291-305. PMID: 15334043.Peer-Reviewed Original ResearchConceptsModifiable risk factorsSleep apneaRisk factorsSleep-related breathing disordersSerious long-term disabilityDevelopment of strokeObstructive sleep apneaCoronary artery diseaseLong-term disabilityManagement of strokePathogenesis of strokeRecent large epidemiological studiesCause of deathLarge epidemiological studiesArterial hypertensionNeurologic recoveryAcute strokeArtery diseaseHemodynamic changesSignificant morbidityBreathing disordersProspective studyCardiac diseaseTherapeutic approachesApnea
2001
Sleep-Related Breathing Disorders and Risk of Stroke
Mohsenin V. Sleep-Related Breathing Disorders and Risk of Stroke. Stroke 2001, 32: 1271-1278. PMID: 11387486, DOI: 10.1161/01.str.32.6.1271.Peer-Reviewed Original ResearchConceptsSleep-related breathing disordersTransient ischemic attackRisk of strokeBreathing disordersRisk factorsSleep apnea disorderIschemic attackApnea disorderHematologic changesHigh prevalenceNormal sleep stateModifiable risk factorsPresence of hypertensionRecent large epidemiological studiesPossible pathogenetic mechanismsLarge epidemiological studiesDiurnal hypertensionCerebral perfusionSignificant morbidityCerebral hemodynamicsPathogenetic mechanismsEpidemiological studiesStrokeHypertensionPatientsSleep-Related Breathing Disorders: Current Treatment Options
Mohsenin V. Sleep-Related Breathing Disorders: Current Treatment Options. Clinical Pulmonary Medicine 2001, 8: 95-100. DOI: 10.1097/00045413-200103000-00006.Peer-Reviewed Original ResearchBreathing disordersTreatment optionsNasal continuous positive airway pressureUpper airway anatomic abnormalitiesContinuous positive airway pressureSleep-related breathing disordersPositive airway pressurePresence of comorbiditiesMandibular advancement deviceCurrent treatment optionsHealth care needsPopular treatment modalityQuality of lifeCerebrovascular complicationsOverall acceptance rateAirway pressureHigh morbidityAnatomic abnormalitiesChronic fatigueTreatment modalitiesCognitive dysfunctionPatient complianceCare needsVolume reduction techniqueRadiofrequency energy
2000
Sleep-related breathing disorders and cardiovascular disease
Roux F, D’Ambrosio C, Mohsenin V. Sleep-related breathing disorders and cardiovascular disease. The American Journal Of Medicine 2000, 108: 396-402. PMID: 10759096, DOI: 10.1016/s0002-9343(00)00302-8.Peer-Reviewed Original ResearchConceptsSleep-related breathing disordersBreathing disordersRisk factorsUpper airway resistance syndromeIndependent risk factorMajority of patientsMajor health problemPulmonary hypertensionSympathetic toneBaroreflex controlIntermittent hypoxiaExcessive daytimeSleep apneaCerebrovascular diseaseResistance syndromeEarly recognitionCardiovascular functionCardiovascular diseaseEpidemiologic studiesNeuropsychological dysfunctionHealth problemsMemory impairmentPoor work performanceDisordersHypertension