2024
Adverse Pregnancy Outcomes and Predicted 30-Year Risk of Maternal Cardiovascular Disease 2–7 Years After Delivery
Venkatesh K, Khan S, Yee L, Wu J, McNeil R, Greenland P, Chung J, Levine L, Simhan H, Catov J, Scifres C, Reddy U, Pemberton V, Saade G, Merz C, Grobman W, Mothers-to-Be A. Adverse Pregnancy Outcomes and Predicted 30-Year Risk of Maternal Cardiovascular Disease 2–7 Years After Delivery. Obstetrics And Gynecology 2024, 143: 775-784. PMID: 38574364, PMCID: PMC11098696, DOI: 10.1097/aog.0000000000005569.Peer-Reviewed Original ResearchConceptsRisk of atherosclerotic CVDAtherosclerotic CVD riskAdverse pregnancy outcomesHypertensive disorders of pregnancyAtherosclerotic CVDCVD riskDisorders of pregnancyPregnancy outcomesHypertensive disordersPreterm birthModified Poisson modelsFramingham risk scoreRisk of CVDRisk of atherosclerotic cardiovascular diseaseMagnitude of riskAbsolute riskAtherosclerotic cardiovascular diseaseSecondary analysisLongitudinal cohortRisk scoreGestational ageGreater riskBaseline covariatesCardiovascular diseaseDisease 2
2023
Researching COVID to enhance recovery (RECOVER) pregnancy study: Rationale, objectives and design
Metz T, Clifton R, Gallagher R, Gross R, Horwitz L, Jacoby V, Martin-Herz S, Peralta-Carcelen M, Reeder H, Beamon C, Chan J, Chang A, Costantine M, Fitzgerald M, Foulkes A, Gibson K, Güthe N, Habli M, Hackney D, Hoffman M, Hoffman M, Hughes B, Katz S, Laleau V, Mallett G, Mendez-Figueroa H, Monzon V, Palatnik A, Palomares K, Parry S, Pettker C, Plunkett B, Poppas A, Reddy U, Rouse D, Saade G, Sandoval G, Schlater S, Sciurba F, Simhan H, Skupski D, Sowles A, Thaweethai T, Thomas G, Thorp J, Tita A, Weiner S, Weigand S, Yee L, Flaherman V, Initiative O. Researching COVID to enhance recovery (RECOVER) pregnancy study: Rationale, objectives and design. PLOS ONE 2023, 18: e0285351. PMID: 38128008, PMCID: PMC10734909, DOI: 10.1371/journal.pone.0285351.Peer-Reviewed Original ResearchMeSH KeywordsAdultCOVID-19FemaleHumansPandemicsPost-Acute COVID-19 SyndromePregnancyProspective StudiesRetrospective StudiesSARS-CoV-2ConceptsSARS-CoV-2 infectionSARS-CoV-2Long-term outcomesMonths of agePregnancy cohortMaternal-Fetal Medicine Units NetworkHealth outcomesSARS-CoV-2 antibody testingAdverse long-term outcomesEunice Kennedy Shriver National InstitutePost-acute sequelaeLong-term sequelaeClinical trial registrationMaternal-child dyadsNational InstituteMulti-site observational studyCalifornia San FranciscoUnique physiologic changesPregnancy modifiesMaternal infectionMultiple gestationsOverall cohortRetrospective cohortAntibody testingLong COVIDSodium intake and the development of hypertensive disorders of pregnancy
Bank T, Grasch J, Chung J, Mercer B, McNeil R, Parry S, Saade G, Shanks A, Silver R, Simhan H, Yee L, Reddy U, Grobman W, Frey H. Sodium intake and the development of hypertensive disorders of pregnancy. American Journal Of Obstetrics & Gynecology MFM 2023, 5: 101166. PMID: 37741626, DOI: 10.1016/j.ajogmf.2023.101166.Peer-Reviewed Original ResearchMeSH KeywordsFemaleHumansHypertension, Pregnancy-InducedInfant, NewbornPre-EclampsiaPregnancyPremature BirthProspective StudiesSodium, DietaryConceptsHypertensive disordersHigh sodium intakeSodium intakeChronic hypertensionNonpregnant populationLow platelet count syndromeNeonatal intensive care unitNulliparous Pregnancy Outcomes StudyElevated liver enzymesGestational age neonatesFood frequency questionnaireLow sodium intakeIncidence risk ratioIntensive care unitWeeks of gestationPregnancy Outcomes StudyLack of associationChi-square testGestational hypertensionNeonatal outcomesNonpregnant stateSodium restrictionFrequency questionnairePreterm birthSingleton pregnanciesRisk Factors for Perinatal Transmission of Hepatitis C Virus
Prasad M, Saade G, Clifton R, Sandoval G, Hughes B, Reddy U, Bartholomew A, Salazar A, Chien E, Tita A, Thorp J, Metz T, Wapner R, Sabharwal V, Simhan H, Swamy G, Heyborne K, Sibai B, Grobman W, El-Sayed Y, Casey B, Parry S, Rathore M, Diaz-Velasco R, Puga A, Wiznia A, Kovacs A, Garry D, Macones G. Risk Factors for Perinatal Transmission of Hepatitis C Virus. Obstetrics And Gynecology 2023, 142: 449-456. PMID: 37590978, PMCID: PMC10437102, DOI: 10.1097/aog.0000000000005306.Peer-Reviewed Original ResearchMeSH KeywordsChildFemaleHepacivirusHepatitis CHumansPregnancyProspective StudiesRisk FactorsRNAUterine HemorrhageConceptsPerinatal transmissionHCV infectionRisk factorsPrimary outcomeHuman Development Maternal-Fetal Medicine Units NetworkMaternal-Fetal Medicine Units NetworkHepatitis C virus infectionEunice Kennedy Shriver National InstituteC virus infectionPerinatal transmission rateWeeks of gestationHigh viral loadHepatitis C virusMonths of lifePositive test resultsAntepartum bleedingViremic participantsVaginal bleedingHCV RNAViremic individualsViral loadC virusObservational studyVirus infectionDemonstrable viremiaAssociation of maternal body mass index with success and outcomes of attempted operative vaginal delivery
Grasch J, Venkatesh K, Grobman W, Silver R, Saade G, Mercer B, Yee L, Scifres C, Parry S, Simhan H, Reddy U, Frey H. Association of maternal body mass index with success and outcomes of attempted operative vaginal delivery. American Journal Of Obstetrics & Gynecology MFM 2023, 5: 101081. PMID: 37422004, DOI: 10.1016/j.ajogmf.2023.101081.Peer-Reviewed Original ResearchMeSH KeywordsBody Mass IndexCesarean SectionDelivery, ObstetricFemaleHumansInfant, NewbornPregnancyPregnancy OutcomeProspective StudiesConceptsMaternal body mass indexBody mass indexOperative vaginal deliveryVaginal delivery attemptComposite maternal morbidityComposite neonatal morbidityVaginal deliveryMass indexNeonatal morbidityCesarean deliveryMaternal morbidityAdverse outcomesSecond-stage cesarean deliveryBody mass index groupsBody mass index categoriesNulliparous Pregnancy Outcomes StudyNonanomalous singleton pregnanciesNeonatal adverse outcomesMultivariable logistic regressionPregnancy Outcomes StudyNulliparous individualsDose-dependent mannerSecondary outcomesSingleton pregnanciesPrimary outcomeAssociation of Living in a Food Desert and Poor Periconceptional Diet Quality in a Cohort of Nulliparous Pregnant Individuals
Venkatesh K, Walker D, Yee L, Wu J, Garner J, McNeil B, Haas D, Mercer B, Reddy U, Silver R, Wapner R, Saade G, Parry S, Simhan H, Lindsay K, Grobman W. Association of Living in a Food Desert and Poor Periconceptional Diet Quality in a Cohort of Nulliparous Pregnant Individuals. Journal Of Nutrition 2023, 153: 2432-2441. PMID: 37364682, PMCID: PMC10447609, DOI: 10.1016/j.tjnut.2023.06.032.Peer-Reviewed Original ResearchConceptsDiet qualityPregnant individualsDietary qualityNulliparous Pregnancy Outcomes StudyWorse dietary qualityAdverse pregnancy outcomesHealthy Eating IndexPregnancy Outcomes StudyAdverse social determinantsFood desertsPregnancy outcomesProspective cohortTotal vegetablesMean HEIMonitoring MothersLowest quartileOutcome studiesPoor dietExcess intakeEmpty caloriesSocial determinantsAdequacy componentsAssessed individualsSupermarket accessFood access indicatorsResearching COVID to Enhance Recovery (RECOVER) adult study protocol: Rationale, objectives, and design
Horwitz L, Thaweethai T, Brosnahan S, Cicek M, Fitzgerald M, Goldman J, Hess R, Hodder S, Jacoby V, Jordan M, Krishnan J, Laiyemo A, Metz T, Nichols L, Patzer R, Sekar A, Singer N, Stiles L, Taylor B, Ahmed S, Algren H, Anglin K, Aponte-Soto L, Ashktorab H, Bassett I, Bedi B, Bhadelia N, Bime C, Bind M, Black L, Blomkalns A, Brim H, Castro M, Chan J, Charney A, Chen B, Chen L, Chen P, Chestek D, Chibnik L, Chow D, Chu H, Clifton R, Collins S, Costantine M, Cribbs S, Deeks S, Dickinson J, Donohue S, Durstenfeld M, Emery I, Erlandson K, Facelli J, Farah-Abraham R, Finn A, Fischer M, Flaherman V, Fleurimont J, Fonseca V, Gallagher E, Gander J, Gennaro M, Gibson K, Go M, Goodman S, Granger J, Greenway F, Hafner J, Han J, Harkins M, Hauser K, Heath J, Hernandez C, Ho O, Hoffman M, Hoover S, Horowitz C, Hsu H, Hsue P, Hughes B, Jagannathan P, James J, John J, Jolley S, Judd S, Juskowich J, Kanjilal D, Karlson E, Katz S, Kelly J, Kelly S, Kim A, Kirwan J, Knox K, Kumar A, Lamendola-Essel M, Lanca M, Lee-Lannotti J, Lefebvre R, Levy B, Lin J, Logarbo B, Logue J, Longo M, Luciano C, Lutrick K, Malakooti S, Mallett G, Maranga G, Marathe J, Marconi V, Marshall G, Martin C, Martin J, May H, McComsey G, McDonald D, Mendez-Figueroa H, Miele L, Mittleman M, Mohandas S, Mouchati C, Mullington J, Nadkarni G, Nahin E, Neuman R, Newman L, Nguyen A, Nikolich J, Ofotokun I, Ogbogu P, Palatnik A, Palomares K, Parimon T, Parry S, Parthasarathy S, Patterson T, Pearman A, Peluso M, Pemu P, Pettker C, Plunkett B, Pogreba-Brown K, Poppas A, Porterfield J, Quigley J, Quinn D, Raissy H, Rebello C, Reddy U, Reece R, Reeder H, Rischard F, Rosas J, Rosen C, Rouphael N, Rouse D, Ruff A, Saint Jean C, Sandoval G, Santana J, Schlater S, Sciurba F, Selvaggi C, Seshadri S, Sesso H, Shah D, Shemesh E, Sherif Z, Shinnick D, Simhan H, Singh U, Sowles A, Subbian V, Sun J, Suthar M, Teunis L, Thorp J, Ticotsky A, Tita A, Tragus R, Tuttle K, Urdaneta A, Utz P, VanWagoner T, Vasey A, Vernon S, Vidal C, Walker T, Ward H, Warren D, Weeks R, Weiner S, Weyer J, Wheeler J, Whiteheart S, Wiley Z, Williams N, Wisnivesky J, Wood J, Yee L, Young N, Zisis S, Foulkes A. Researching COVID to Enhance Recovery (RECOVER) adult study protocol: Rationale, objectives, and design. PLOS ONE 2023, 18: e0286297. PMID: 37352211, PMCID: PMC10289397, DOI: 10.1371/journal.pone.0286297.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 infectionRisk factorsClinical risk factorsPost-acute sequelaePrimary study outcomeProportional hazards regressionCommunity-based outreachMulti-site observational studyPASC symptomsQuarterly questionnairesRetrospective cohortVaccination statusOrgan dysfunctionAcute phaseLong COVIDHazards regressionEligible participantsTreatment optionsPrior infectionStudy protocolClinical trialsNew symptomsLongitudinal cohortLaboratory examinationsObservational studyDevelopment of a Definition of Postacute Sequelae of SARS-CoV-2 Infection
Thaweethai T, Jolley S, Karlson E, Levitan E, Levy B, McComsey G, McCorkell L, Nadkarni G, Parthasarathy S, Singh U, Walker T, Selvaggi C, Shinnick D, Schulte C, Atchley-Challenner R, Horwitz L, Foulkes A, Aberg J, Adolphi N, Ahirwar S, Ahmed S, Ahuja N, Aikawa M, Akerlundh A, Akintonwa T, Al-Jadiri A, Alekhina N, Algren H, Alshawabkeh A, Ammar N, Anand A, Anderson B, Aponte-Soto L, Aschner J, Atha M, Atz A, Aupperle R, Ayache M, Azziz-Baumgartner E, Bailey L, Baker F, Balaraman V, Bandy J, Banerjee D, Barch D, Bardes J, Barlocker J, Barr R, Baskin-Sommers A, Basu S, Battaglia T, Baucom L, Beamon C, Beaty C, Beckmann N, Berry J, Bhadelia N, Bhargava D, Bhuiyan S, Bian J, Bime C, Bjork J, Black L, Blish C, Block J, Bogie A, Bolliger D, Bonaventura W, Bose-Brill S, Bower M, Boyd A, Boyineni J, Bradfute S, Bramante C, Brannock M, Bremner J, Brosnahan S, Buchbinder N, Bueler E, Buhimschi I, Bukulmez H, Bunnell H, Buse J, Calhoun E, Cao T, Carrithers M, Carton T, Case A, Casey B, Casimero F, Castro L, Cato T, Ceger P, Cerullo C, Chang L, Chang A, Chebrolu P, Chen Y, Chen L, Chen B, Chestek D, Chew R, Chisolm D, Chow D, Chrisant M, Christakis D, Chute C, Cicek M, Clark C, Clark D, Clarke G, Clouser K, Connors T, Cook J, Coombs K, Cordon-Cardo C, Costello J, Cottrell L, Cowan K, Cowell L, Cranford S, Cronin J, Cummins M, Curry H, D'Sa V, Dabney S, Daniel C, Dapretto M, Darbar D, Darden P, Dasgupta R, Dasgupta S, Davis Blakley F, Dea K, Deakyne Davies S, Decker L, DeFronzo R, Dehority W, Deitchman A, del Alcazar J, Del Boccio P, del Rio C, Del Rios M, DeLisa J, Deoni S, Diaz M, Dickinson J, Dionne A, Diviak K, Donohue S, Downey M, Dozor A, Dreyer B, Dummer K, Durstenfeld M, Dworkin M, Edmonds S, Elias M, Elifritz J, Ellingworth E, Elliott A, Ellison A, Enger M, Espinosa J, Esquenazi-Karonika S, Evans M, Evans D, Facelli J, Fang C, Faustino E, Fayad Lara M, Feldman C, Fiks A, Fineman R, Finn A, Fischer M, Fitzgerald M, Flaherman V, Flotte T, Forsha D, Fortune M, Foxe J, Franks N, Freedman M, Freeland C, Friedman N, Fry G, Gage Witvliet M, Gallagher E, Gallagher R, Garavan H, Gaur S, Gee D, Gennaro M, Gerald L, Ghosh S, Giacino J, Girvin A, Godfrey S, Goldberg M, Goodman S, Gordon H, Gouripeddi R, Graham P, Granger J, Gray K, Greimes T, Gross R, Guthe N, Gutter E, Haasnoot S, Hadley E, Haendel M, Hafner S, Halabi K, Hanley P, Harahsheh A, Harkins M, Hartwig K, Hasbani K, Hasek S, Hauser K, Heath A, Hebson C, Heitzeg M, Hendrickson M, Henrich T, Hernandez-Romieu A, Hester C, Higginbotham M, Hill S, Hirabayashi K, Ho O, Hobart-Porter L, Hoffman M, Holtcamp M, Hong T, Horne B, Horowitz C, Hsia D, Hsu H, Hsue P, Huentelman M, Huerta B, Huling J, Hummel K, Iacono W, Ibanez A, Ibeawuchi C, Irby K, Ismail N, Jacobus J, Jacoby V, Jason L, Javia V, Jennette K, Jernigan T, Jiang S, Jing N, Johnny J, Johnson N, Johnson B, Johnson B, Jone P, Judd S, Juskowich J, Kabagambe E, Kaelber D, Kanjilal D, Kansal M, Kasmarcak T, Kaufman D, Kawakami R, Kellogg D, Kent D, Kewlani D, Khullar D, Kim K, Kim A, Kinser P, Kleinman L, Klerman E, Kluko M, Knight S, Kobayashi M, Kopp K, Koropsak M, Kosut J, Kraig E, Krausert A, Krieger A, Krishna H, Krishnamoorthy A, Krishnan S, Lahs J, Laird A, Laleau V, Lamendola-Essel M, Landeo-Gutierrez J, Lang S, Larson C, Lash J, Lasky-Su J, Laynor G, Lee S, Lee G, Lee F, Lee M, Leese P, Lefebvre R, Levreault A, Lewis K, Li L, Lim P, Lin J, Lisdahl K, Litvack M, Liu X, Lloyd J, Logue J, Loomba J, Lorman V, Lu Y, Ludwig K, Lutz A, Mack J, Mahmoud A, Maier C, Malakooti S, Malchenko S, Mallett G, Maranga G, Martel M, Martin-Herz S, Martinez-Lage M, Maughan C, Mauntel-Medici C, May H, Mayer K, Mazzotti D, McCallum C, McCrindle B, McCulloh R, McDonald D, McInnis S, McMurry J, Mejias A, Melamed J, Menchaca M, Mendelsohn A, Miele L, Miglis M, Milne C, Milner J, Mitchell R, Mittleman M, Mohandas S, Monteiro J, Monzon V, Moreno D, Morgan L, Morozyuk D, Morse K, Moyneur E, Mudumbi P, Müller-Oehring E, Muramatsu N, Musick H, Nagavedu K, Nahin E, Nambiar A, Natelson B, Neale M, Ness-Cochinwala M, Newburger J, Newman L, Nguyen A, Nichols L, Nolan S, Noland S, Novak R, O'Connor G, O'Keefe J, Ogbogu P, Oliveira C, Oster M, Padera R, Paik H, Pajor N, Pan H, Pant D, Partridge A, Patel P, Patel S, Patel K, Paulus M, Payne R, Pearman A, Peralta-Carcelen M, Perez N, Pfaff E, Pillers D, Pitsch C, Pliskin N, Portman M, Postelnicu R, Potter J, Prabhakar B, Prahalad P, Prasad B, Predki B, Preiss A, Prendergast H, Quinn D, Quintana Y, Rabideau D, Radosta J, Radwell J, Raissy H, Ramchandran R, Randall I, Rao S, Rapkiewicz A, Rasmussen S, Razzaghi H, Rebello C, Rebolledo P, Reddy N, Reddy U, Reedy C, Rehman J, Reichard R, Reid K, Reusch J, Rhee K, Rice M, Rizzo J, Roan N, Robarts P, Roberts T, Rochez N, Rodgers K, Rogerson C, Romero M, Rosas J, Rosenzweig E, Rothman R, Rouphael N, Russell M, Rutherfoord M, Sabati A, Sader S, Salehi M, Salisbury A, Sampson B, Sanil Y, Sato A, Saydah S, Schechter M, Schenck E, Schlepphorst K, Schuchard J, Schuh T, Sculley J, Seifert A, Sekar A, Selvarangan R, Seshadri S, Sesso H, Shah D, Shakti D, Shapiro N, Sharma S, Sharma K, Sharma S, Sharma K, Shaw G, Shemesh E, Shen Y, Shenkman E, Shiau S, Siciliano M, Simsir A, Smith V, Snowden J, Solomon I, Spikes L, Squeglia L, Srivastava S, St. Jean M, Stapleford K, Stein C, Stevenson M, Stewart de Ramirez S, Stiles L, Stock A, Stockwell M, Stone J, Stratford J, Stürmer T, Subbian V, Sun J, Suthar M, Sylvera A, Systrom D, Szmuszkovicz J, Talavera-Barber M, Tantisira K, Tartt N, Terlinde T, Teufel R, Thacker D, Thakrar M, Thibodeau S, Thomas G, Thomason M, Tong J, Torres R, Traenkner J, Tragus R, Trinity J, Tronieri J, Troxel A, Truong J, Truong D, Tsevat J, Udosen M, Unterberger K, Utz P, Vaccarino V, Vallejos B, Vanden Hoek T, Vangeepuram N, Varma J, Vernon S, Vidal C, Vivensi S, Vohra A, Wagner L, Wang F, Warburton D, Warner M, Watkins R, Watson S, Webb R, Weeks R, Weiner M, Werzberger A, West S, Weyer J, Wheeler J, Wilkins K, Williams N, Williams C, Wimberly E, Winter T, Woller S, Wong R, Wood J, Wood J, Wood M, Wu Q, Xia Y, Xu J, Yang S, Yin H, Yin H, Yoo Y, Young C, Young N, Zang C, Zempsky W, Zhang B, Zhang Y, Zhang D, Zimmerman E, Andrefsky J, Marrazzo J, Dixon J, Gale L, Maholovich P, Sudhindra P, Thompson T, Sheehan E, Parada A, Knowlton K, Anderson J, McIntyre M, McCandless S, Montoya S, Davis D, Spanier E, Wodushek T, Sokol R, Maldonado Y, Jacobson K, Jia X, Scott J, Quintero O, Haddad F, Valantine H, Zamanian R, Pathak D, Boyce J, Facco F, Hankle S, Vargo J, Campbell D, Armstrong D, Mann M, Burrell N, Bartholomew A, Grobman W, Cackovic B, Klopfenstein B, Weigand S, Snow E, Fennig K, Esplin M, Lamb D, Nelsen A, Phipers J, Fischer L, Docter O, Brown J, DeMartino A, Allard D, Miller E, Bousleiman S, Loffredo M, Vanneman A, Beche I, Chan-Akeley R, Pacheco L, DeVolder J, Salazar A, Thibodeaux L, Cornwell J, Nounes A, Sweet E, Pierse A, Desantis B, Gill-Jones P, Hackney D, Chauhan S, Ortiz F, Treadway J, Rugerio J, Clark K, Leatherland M, Timlin S, Grinnan C, Ferrara J, Kominiarek M, Jones D, Reynolds T, Kearns K, Saffian E, Karasti M, Pizzi C, Filipczak A, Long E, Mitchell M, Barrett K, Mullowney C, Macones G, Alba G, Alicic R, Altman N, Anglin K, Argueta U, Ashktorab H, Baslet G, Bassett I, Bateman L, Bedi B, Bhattacharyya S, Bind M, Blomkalns A, Bonilla H, Brim H, Bush P, Castro M, Chan J, Charney A, Chen P, Chibnik L, Chu H, Clifton R, Costantine M, Cribbs S, Davila Nieves S, Deeks S, Duven A, Emery I, Erdmann N, Erlandson K, Ernst K, Farah-Abraham R, Farner C, Feuerriegel E, Fleurimont J, Fonseca V, Franko N, Gainer V, Gander J, Gardner E, Geng L, Gibson K, Go M, Goldman J, Grebe H, Greenway F, Habli M, Hafner J, Han J, Hanson K, Heath J, Hernandez C, Hess R, Hodder S, Hoffman M, Hoover S, Huang B, Hughes B, Jagannathan P, John J, Jordan M, Katz S, Kaufman E, Kelly J, Kelly S, Kemp M, Kirwan J, Klein J, Knox K, Krishnan J, Kumar A, Laiyemo A, Lambert A, Lanca M, Lee-Iannotti J, Logarbo B, Longo M, Luciano C, Lutrick K, Maley J, Mallett G, Marathe J, Marconi V, Marshall G, Martin C, Matusov Y, Mehari A, Mendez-Figueroa H, Mermelstein R, Metz T, Morse R, Mosier J, Mouchati C, Mullington J, Murphy S, Neuman R, Nikolich J, Ofotokun I, Ojemakinde E, Palatnik A, Palomares K, Parimon T, Parry S, Patterson J, Patterson T, Patzer R, Peluso M, Pemu P, Pettker C, Plunkett B, Pogreba-Brown K, Poppas A, Quigley J, Reddy U, Reece R, Reeder H, Reeves W, Reiman E, Rischard F, Rosand J, Rouse D, Ruff A, Saade G, Sandoval G, Santana J, Schlater S, Sciurba F, Shepherd F, Sherif Z, Simhan H, Singer N, Skupski D, Sowles A, Sparks J, Sukhera F, Taylor B, Teunis L, Thomas R, Thorp J, Thuluvath P, Ticotsky A, Tita A, Tuttle K, Urdaneta A, Valdivieso D, VanWagoner T, Vasey A, Verduzco-Gutierrez M, Wallace Z, Ward H, Warren D, Weiner S, Welch S, Whiteheart S, Wiley Z, Wisnivesky J, Yee L, Zisis S. Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection. JAMA 2023, 329: 1934-1946. PMID: 37278994, PMCID: PMC10214179, DOI: 10.1001/jama.2023.8823.Peer-Reviewed Original ResearchMeSH KeywordsAdultCohort StudiesCOVID-19Disease ProgressionFatigueFemaleHumansMaleMiddle AgedPost-Acute COVID-19 SyndromeProspective StudiesSARS-CoV-2ConceptsSARS-CoV-2 infectionCohort studyPostacute sequelaeProspective observational cohort studyAcute symptom onsetObservational cohort studyProspective cohort studyAdjusted odds ratioDays of infectionSelf-reported symptomsSurvey 6 monthsNumber of infectionsBrain fogChest painChronic coughGastrointestinal symptomsSymptom onsetVaccination statusAcute infectionPostexertional malaiseClinical featuresLong COVIDNew symptomsOdds ratioAbnormal movementsAssociation of Neighborhood Socioeconomic Disadvantage and Postpartum Readmission
Meiman J, Grobman W, Haas D, Yee L, Wu J, McNeil B, Wu J, Mercer B, Simhan H, Reddy U, Silver R, Parry S, Saade G, Lynch C, Venkatesh K. Association of Neighborhood Socioeconomic Disadvantage and Postpartum Readmission. Obstetrics And Gynecology 2023, 141: 967-970. PMID: 37026732, PMCID: PMC10147577, DOI: 10.1097/aog.0000000000005151.Peer-Reviewed Original ResearchConceptsArea Deprivation IndexPostpartum readmissionNeighborhood socioeconomic disadvantageNeighbourhood deprivationSocioeconomic disadvantageWeeks of deliveryAdverse social determinantsProspective cohortPostpartum careDelivery dischargePregnant individualsReadmissionPoisson regressionSecondary analysisSocial determinantsDeprivation indexAssessed individualsRiskDeprivationIndividualsPostpartumCohortQuartileWeeksCare
2022
Association of a Mediterranean Diet Pattern With Adverse Pregnancy Outcomes Among US Women
Makarem N, Chau K, Miller E, Gyamfi-Bannerman C, Tous I, Booker W, Catov J, Haas D, Grobman W, Levine L, McNeil R, Merz C, Reddy U, Wapner R, Wong M, Bello N. Association of a Mediterranean Diet Pattern With Adverse Pregnancy Outcomes Among US Women. JAMA Network Open 2022, 5: e2248165. PMID: 36547978, PMCID: PMC9857221, DOI: 10.1001/jamanetworkopen.2022.48165.Peer-Reviewed Original ResearchConceptsAdverse pregnancy outcomesMediterranean diet patternTime of conceptionPregnancy outcomesDiet patternLower oddsAMED scoresGestational diabetesCohort studyUS womenLower riskRisk of APOsPrepregnancy body mass indexCardiovascular disease risk factorsSemiquantitative food frequency questionnaireAlternate Mediterranean diet scoreNulliparous Pregnancy Outcomes StudyLowest AMED scoresGestational age infantsDisease risk factorsDose-response associationFood frequency questionnaireMediterranean diet scoreBody mass indexCause of morbidityAssociation of Social Determinants of Health and Clinical Factors with Postpartum Hospital Readmissions among Nulliparous Individuals
Kumar N, Grobman W, Haas D, Silver R, Reddy U, Simhan H, Wing D, Mercer B, Yee L. Association of Social Determinants of Health and Clinical Factors with Postpartum Hospital Readmissions among Nulliparous Individuals. American Journal Of Perinatology 2022, 40: 348-355. PMID: 36427510, DOI: 10.1055/s-0042-1758485.Peer-Reviewed Original ResearchConceptsPostpartum readmissionSocial determinantsHypertensive disordersHigher oddsMulticenter prospective cohort studyPostpartum hospital readmissionProspective cohort studyInitial hospital dischargeHemorrhage requiring transfusionSuch risk factorsAntecedent diagnosisHDP patientsNulliparous participantsGestational diabetesIntrapartum complicationsPerinatal morbidityCesarean deliveryCohort studyHospital dischargeClinical factorsHospital readmissionPrimary outcomeBivariable analysisModifiable factorsInsurance statusAssociation of N-Terminal Pro–Brain Natriuretic Peptide Concentration in Early Pregnancy With Development of Hypertensive Disorders of Pregnancy and Future Hypertension
Hauspurg A, Marsh D, McNeil R, Bairey Merz C, Greenland P, Straub A, Rouse C, Grobman W, Pemberton V, Silver R, Chen Y, Mercer B, Levine L, Hameed A, Hoffman M, Simhan H, Catov J, Reddy U, Willinger M, Davis M, Laposky A, Iams J, Dalton W, Latimer C, Polito L, Louis J, Wapner R, Fuchs K, Torres C, Lynch S, Onativia A, DiVito M, Nhan-Chang C, Basner R, Haas D, Foroud T, Perkins E, Barnes S, Winters A, McCormick C, Schubert F, Caritis S, Bickus M, Speer P, Emery S, Daftary A, Facco F, Peaceman A, Zee P, Campbell P, Shepard J, Williams C, Wing D, Wadhwa P, Nageotte M, Chung J, Rumney P, Porto M, Pham V, Parry S, Ludmir J, Elovitz M, Peters M, Araujo B, Pien G, Esplin M, Vorwaller K, Postma J, Morby V, Williams M, Meadows L, Parker C, Koch M, McFadden D, Alexander B, Yetukuri V, Hunter S, Holder T, Franklin H, DeCain M, Griggs C, Redline S, Mobley D, Surovec S, Ulanski J, Saade G. Association of N-Terminal Pro–Brain Natriuretic Peptide Concentration in Early Pregnancy With Development of Hypertensive Disorders of Pregnancy and Future Hypertension. JAMA Cardiology 2022, 7: 268-276. PMID: 35044418, PMCID: PMC8771430, DOI: 10.1001/jamacardio.2021.5617.Peer-Reviewed Original ResearchConceptsHigher NT-proBNP concentrationsNT-proBNP concentrationsHypertensive disordersSubclinical cardiac dysfunctionEarly pregnancyYear post partumHypertension 2Lower riskPregnancy outcomesCohort studyCardiac dysfunctionNatriuretic peptideN-terminal pro-brain natriuretic peptide concentrationN-terminal pro-brain natriuretic peptideEarly pregnancy body mass indexProspective multicenter observational studyPro-brain natriuretic peptidePost partumNulliparous Pregnancy Outcomes StudyFirst-trimester blood samplesAdverse pregnancy outcomesMulticenter observational studyFuture cardiovascular diseaseNatriuretic peptide concentrationsCardiovascular disease risk
2020
Stillbirth and fetal anomalies: secondary analysis of a case–control study
Son S, Allshouse A, Page J, Debbink M, Pinar H, Reddy U, Gibbins K, Stoll B, Parker C, Dudley D, Varner M, Silver R. Stillbirth and fetal anomalies: secondary analysis of a case–control study. BJOG An International Journal Of Obstetrics & Gynaecology 2020, 128: 252-258. PMID: 32946651, PMCID: PMC7902300, DOI: 10.1111/1471-0528.16517.Peer-Reviewed Original Research
2018
Smith–Lemli–Opitz Mutations in Unexplained Stillbirths
Gibbins KJ, Reddy UM, Saade GR, Goldenberg RL, Dudley DJ, Parker CB, Thorsten V, Pinar H, Bukowski R, Hogue CJ, Silver RM. Smith–Lemli–Opitz Mutations in Unexplained Stillbirths. American Journal Of Perinatology 2018, 35: 936-939. PMID: 29433144, PMCID: PMC6060008, DOI: 10.1055/s-0038-1626705.Peer-Reviewed Original ResearchConceptsUnexplained stillbirthLive birthsPopulation-based case-control studyCase-control studySmith-LemliAutosomal recessive syndromeObstetric complicationsHistologic featuresExon 3Placental tissueStillbirthRecessive syndromeDeoxyribonucleic acidStrong associationBidirectional sequencingDHCR7 mutationsCompound heterozygotesSyndromeCholesterol biosynthesisOpitz syndromeHomozygote frequencyBirthRepresentative sampleSLOS mutationsDHCR7
2015
Predictors of response to 17-alpha hydroxyprogesterone caproate for prevention of recurrent spontaneous preterm birth
Manuck TA, Esplin MS, Biggio J, Bukowski R, Parry S, Zhang H, Huang H, Varner MW, Andrews W, Saade G, Sadovsky Y, Reddy UM, Ilekis J, Research E. Predictors of response to 17-alpha hydroxyprogesterone caproate for prevention of recurrent spontaneous preterm birth. American Journal Of Obstetrics And Gynecology 2015, 214: 376.e1-376.e8. PMID: 26692181, PMCID: PMC4803498, DOI: 10.1016/j.ajog.2015.12.010.Peer-Reviewed Original ResearchConceptsSpontaneous preterm birthPrevious spontaneous preterm birthRecurrent spontaneous preterm birthDelivery gestational ageRecurrent preterm birthPreterm birthSimilar gestational ageGestational ageHydroxyprogesterone caproateSingleton spontaneous preterm birthEarly spontaneous preterm birthFirst-degree family historyPreterm birth preventionHigh-risk womenPlanned secondary analysisPredictors of responseChi-square testPenultimate pregnancyPregnancy characteristicsNeonatal morbidityPregnancy coursePreterm pregnanciesBirth preventionCurrent pregnancyRegression modelsCluster analysis of spontaneous preterm birth phenotypes identifies potential associations among preterm birth mechanisms
Esplin MS, Manuck TA, Varner MW, Christensen B, Biggio J, Bukowski R, Parry S, Zhang H, Huang H, Andrews W, Saade G, Sadovsky Y, Reddy UM, Ilekis J. Cluster analysis of spontaneous preterm birth phenotypes identifies potential associations among preterm birth mechanisms. American Journal Of Obstetrics And Gynecology 2015, 213: 429.e1-429.e9. PMID: 26070700, PMCID: PMC4556543, DOI: 10.1016/j.ajog.2015.06.011.Peer-Reviewed Original ResearchConceptsSpontaneous preterm birthDecidual hemorrhagePlacental dysfunctionProspective case-control multicenter studyCase-control multicenter studyPremature membrane ruptureGroup of womenCommon biologic pathwaysMaternal comorbiditiesPreterm singletonsPreterm birthWeeks' gestationMulticenter studyMaternal stressSecondary analysisBiologic pathwaysFamilial factorsGenetic factorsWomenPhenotypic profileGestationInfectionMembrane ruptureCommon mechanismPhenotypeThe phenotype of spontaneous preterm birth: application of a clinical phenotyping tool
Manuck TA, Esplin MS, Biggio J, Bukowski R, Parry S, Zhang H, Huang H, Varner MW, Andrews W, Saade G, Sadovsky Y, Reddy UM, Ilekis J, Research E. The phenotype of spontaneous preterm birth: application of a clinical phenotyping tool. American Journal Of Obstetrics And Gynecology 2015, 212: 487.e1-487.e11. PMID: 25687564, PMCID: PMC4456184, DOI: 10.1016/j.ajog.2015.02.010.Peer-Reviewed Original ResearchMeSH KeywordsAdultCase-Control StudiesFemaleGestational AgeHumansPhenotypePregnancyPremature BirthProspective StudiesRisk FactorsUnited StatesConceptsSpontaneous preterm birthEarly spontaneous preterm birthInfection/inflammationDecidual hemorrhageGestational ageCervical insufficiencyPreterm birthWeeks' gestationPlacental dysfunctionWhite womenMaternal stressSingleton spontaneous preterm birthDelivery gestational ageFinal common pathwayAfrican American womenMaternal comorbiditiesPremature ruptureProspective studyPlanned analysisUterine distentionClinical dataMultiple possible causesGestationHemorrhageComprehensive classification systemThe association of beta‐2 adrenoceptor genotype with short‐cervix mediated preterm birth: a case–control study
Miller R, Smiley R, Thom E, Grobman W, Iams J, Mercer B, Saade G, Tita A, Reddy U, Rouse D, Sorokin Y, Blackwell S, Esplin, Tolosa J, Caritis, Network E. The association of beta‐2 adrenoceptor genotype with short‐cervix mediated preterm birth: a case–control study. BJOG An International Journal Of Obstetrics & Gynaecology 2015, 122: 1387-1394. PMID: 25600430, PMCID: PMC4508241, DOI: 10.1111/1471-0528.13243.Peer-Reviewed Original ResearchConceptsShort cervixCervical lengthAR genotypeMaternal-Fetal Medicine Units NetworkEunice Kennedy Shriver National InstituteNormal cervical lengthShort cervical lengthShort cervix groupPreterm birth riskCase-control studyRace/ethnicitySpontaneous PTBNulliparous womenPregnancy outcomesPreterm birthTransvaginal sonogramsPrimary outcomePTB riskSecond trimesterAncillary studiesChild healthBirth riskCervixAdrenoceptor genotypeControl group
2014
Maternal serum serpin B7 is associated with early spontaneous preterm birth
Parry S, Zhang H, Biggio J, Bukowski R, Varner M, Xu Y, Andrews WW, Saade GR, Esplin MS, Leite R, Ilekis J, Reddy UM, Sadovsky Y, Blair IA, Research E. Maternal serum serpin B7 is associated with early spontaneous preterm birth. American Journal Of Obstetrics And Gynecology 2014, 211: 678.e1-678.e12. PMID: 24954659, PMCID: PMC4254341, DOI: 10.1016/j.ajog.2014.06.035.Peer-Reviewed Original ResearchConceptsSpontaneous preterm birthEarly spontaneous preterm birthPreterm birthMaternal serumSerum samplesPrevious spontaneous preterm birthSubsequent preterm deliveryProtein expressionLower gestational ageGestational age windowsCase-control studyCandidate protein expressionSerum proteomic analysisIndividual serum samplesPooled serum samplesSpontaneous pretermPreterm deliveryWeeks' gestationGestational ageTerm deliveryPregnant womenSerum biomarkersSerum concentrationsFetal membranesClinical sites
2011
Stillbirth Collaborative Research Network: design, methods and recruitment experience
Parker CB, Hogue CJ, Koch MA, Willinger M, Reddy UM, Thorsten VR, Dudley DJ, Silver RM, Coustan D, Saade GR, Conway D, Varner MW, Stoll B, Pinar H, Bukowski R, Carpenter M, Goldenberg R, Network F. Stillbirth Collaborative Research Network: design, methods and recruitment experience. Paediatric And Perinatal Epidemiology 2011, 25: 425-435. PMID: 21819424, PMCID: PMC3665402, DOI: 10.1111/j.1365-3016.2011.01218.x.Peer-Reviewed Original ResearchConceptsStillbirth Collaborative Research NetworkPost-mortem examinationMaternal interviewsPlacental pathological examinationMedical record abstractionCase-control studyCase-control study participantsTime of deliveryHigher consent ratesGeographical catchment areasRecruitment experienceRecruitment hospitalChart abstractionProspective enrollmentPlacental pathologyRecord abstractionWeeks' gestationPathological examinationRisk factorsConsent ratesLivebirthsStillbirthClinical sitesStudy participantsAdditional surveillance