2024
Blood Pressure Control in Pregnant Patients with Chronic Hypertension and Diabetes: Should <130/80 be the Target?
Harper L, Kuo H, Boggess K, Dugoff L, Sibai B, Lawrence K, Hughes B, Bell J, Aagaard K, Edwards R, Gibson K, Haas D, Plante L, Metz T, Casey B, Esplin S, Longo S, Hoffman M, Saade G, Hoppe K, Foroutan J, Tuuli M, Owens M, Simhan H, Frey H, Rosen T, Palatnik A, August P, Reddy U, Kinzler W, Su E, Krishna I, Nguyen N, Norton M, Skupski D, El-Sayed Y, Galis Z, Ambalavanan N, Oparil S, Szychowski J, Tita A. Blood Pressure Control in Pregnant Patients with Chronic Hypertension and Diabetes: Should <130/80 be the Target? American Journal Of Obstetrics And Gynecology 2024 PMID: 39288828, DOI: 10.1016/j.ajog.2024.09.006.Peer-Reviewed Original ResearchTarget blood pressureNeonatal intensive care unitLow blood pressure groupBlood pressure groupPerinatal outcomesAverage blood pressureChronic hypertensionMm HgBlood pressureCesarean deliveryNeonatal deathDiastolic BPRisk of NICU admissionCompare perinatal outcomesEvaluate risk ratiosLt;130/80 mm HgPreterm birth <Adverse perinatal outcomesMultivariable log-binomial regression modelsGoal blood pressureAverage diastolic BPPrimary composite outcomeSystolic BP <Log-binomial regression modelsAntenatal blood pressure
2023
Cannabis Exposure and Adverse Pregnancy Outcomes Related to Placental Function
Metz T, Allshouse A, McMillin G, Greene T, Chung J, Grobman W, Haas D, Mercer B, Parry S, Reddy U, Saade G, Simhan H, Silver R. Cannabis Exposure and Adverse Pregnancy Outcomes Related to Placental Function. JAMA 2023, 330: 2191-2199. PMID: 38085313, PMCID: PMC10716715, DOI: 10.1001/jama.2023.21146.Peer-Reviewed Original ResearchConceptsPrimary composite outcomeAdverse pregnancy outcomesComposite outcomeFirst trimesterCannabis exposurePregnancy outcomesCannabis usePlacental functionPropensity score-weighted analysisNulliparous Pregnancy Outcomes StudyOngoing exposureMaternal cannabis useUrine cotinine assayUrine samplesMedical record abstractionPregnancy outcome dataGestational-age birthsBody mass indexGestational age windowsPregnancy Outcomes StudyUS medical centersOngoing cannabis useAdjudication of outcomesMaternal cannabisHypertensive disorders