Complex interactions in EML cell stimulation by stem cell factor and IL-3
Ye ZJ, Gulcicek E, Stone K, Lam T, Schulz V, Weissman SM. Complex interactions in EML cell stimulation by stem cell factor and IL-3. Proceedings Of The National Academy Of Sciences Of The United States Of America 2011, 108: 4882-4887. PMID: 21383156, PMCID: PMC3064389, DOI: 10.1073/pnas.1018002108.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigens, CD34Cell LineHematopoietic Stem CellsHumansInterleukin-3MiceProto-Oncogene Proteins c-kitReceptors, Interleukin-3Stem Cell FactorConceptsStem cell factorHematopoietic precursor cell lineIL-3Cell factorPrecursor cell lineIL-3 receptorEML cellsTyrosine phosphorylationSubset of cellsSCF receptorDirect interactionCell linesMixed populationRelative levelsCell stimulationCellsComplex interactionsHeterogeneous mixtureReceptorsPhosphorylationLymphoid cells