Protective Nature of Platelet-Rich Plasma Against Chondrocyte Death When Combined With Corticosteroids or Local Anesthetics
Durant TJ, Dwyer CR, McCarthy MB, Cote MP, Bradley JP, Mazzocca AD. Protective Nature of Platelet-Rich Plasma Against Chondrocyte Death When Combined With Corticosteroids or Local Anesthetics. The American Journal Of Sports Medicine 2016, 45: 218-225. PMID: 27582279, DOI: 10.1177/0363546516664161.Peer-Reviewed Original ResearchConceptsPlatelet-rich plasmaUse of corticosteroidsLocal anestheticsChondrocyte viabilityEffect of PRPAddition of PRPTemporary symptomatic reliefRelief of painLocal anesthetic treatmentAnti-inflammatory characteristicsCytotoxic effectsPresence of PRPChronic progressive natureImprovement of functionChondrocyte proliferationRange of motionSymptomatic reliefPeripheral bloodCorticosteroidsAnesthetic treatmentProliferation of chondrocytesTissue atrophyAnestheticsProgressive natureThymidine assay