2015
Effect of empirical treatment on outcomes of clinical trials of diagnostic assays for tuberculosis
Menzies NA, Cohen T, Murray M, Salomon JA. Effect of empirical treatment on outcomes of clinical trials of diagnostic assays for tuberculosis. The Lancet Infectious Diseases 2015, 15: 16-17. PMID: 25541164, DOI: 10.1016/s1473-3099(14)71026-6.Peer-Reviewed Original ResearchAntitubercular AgentsHumansMycobacterium tuberculosisReal-Time Polymerase Chain ReactionTuberculosis
2012
Population Health Impact and Cost-Effectiveness of Tuberculosis Diagnosis with Xpert MTB/RIF: A Dynamic Simulation and Economic Evaluation
Menzies NA, Cohen T, Lin HH, Murray M, Salomon JA. Population Health Impact and Cost-Effectiveness of Tuberculosis Diagnosis with Xpert MTB/RIF: A Dynamic Simulation and Economic Evaluation. PLOS Medicine 2012, 9: e1001347. PMID: 23185139, PMCID: PMC3502465, DOI: 10.1371/journal.pmed.1001347.Peer-Reviewed Original ResearchConceptsMultidrug-resistant TBCost-effectiveness ratioInitial diagnosisXpert MTB/RIF testMTB/RIF testXpert MTB/RIFIntroduction of XpertTB natural historyTB-HIV coinfectionMultidrug-resistant tuberculosisHigh HIV prevalenceMTB/RIFHealth system costsImplementation of XpertHealth impactsPopulation health impactCost-effectiveness resultsLong-term transmission dynamicsWorld Health OrganizationAntiretroviral therapyTB casesTB deathsTB morbidityHIV prevalenceRIF test