2014
The Impact of Antiretroviral Therapy on Mortality in HIV Positive People during Tuberculosis Treatment: A Systematic Review and Meta-Analysis
Odone A, Amadasi S, White RG, Cohen T, Grant AD, Houben RM. The Impact of Antiretroviral Therapy on Mortality in HIV Positive People during Tuberculosis Treatment: A Systematic Review and Meta-Analysis. PLOS ONE 2014, 9: e112017. PMID: 25391135, PMCID: PMC4229142, DOI: 10.1371/journal.pone.0112017.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Retroviral AgentsComorbidityData Interpretation, StatisticalHIV InfectionsHIV SeropositivityHumansRisk FactorsTreatment OutcomeTuberculosisConceptsHIV-positive peopleAntiretroviral therapyTB treatmentTuberculosis treatmentSystematic reviewHIV-positive TB casesCoverage of ARTRisk of deathMain outcome measuresOutcomes of interestTB casesDual epidemicsTB therapyRelative riskOutcome measuresPooled estimatesStudy populationProportion of individualsFatality ratioPositive peopleMeta-AnalysisART statusClinical settingManual searchMortalityThe potential effects of changing HIV treatment policy on tuberculosis outcomes in South Africa
Pretorius C, Menzies NA, Chindelevitch L, Cohen T, Cori A, Eaton JW, Fraser C, Gopalappa C, Hallett TB, Salomon JA, Stover J, White RG, Dodd PJ. The potential effects of changing HIV treatment policy on tuberculosis outcomes in South Africa. AIDS 2014, 28: s25-s34. PMID: 24468944, DOI: 10.1097/qad.0000000000000085.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyTB incidenceART expansionHIV treatment policyHIV-positive individualsART eligibility criteriaTuberculosis outcomesART eligibilitySurvival benefitTB burdenTB casesHIV transmissionART coverageHIV treatmentHIV epidemicMortality reductionPositive individualsEligibility criteriaTreatment policyART servicesTuberculosisIncidenceCurrent eligibilityIndependent mathematical modelsRecent findings
2010
Prolonged deferral of antiretroviral therapy in the SAPIT trial: Did we need a clinical trial to tell us that this would increase mortality?
Boulle A, Clayden P, Cohen K, Cohen T, Conradie F, Dong K, Geffen N, Grimwood A, Hurtado R, Kenyon C, Lawn S, Maartens G, Meintjes G, Mendelson M, Murray M, Rangaka M, Sanne I, Spencer D, Taljaard J, Variava E, Venter WD, Wilson D. Prolonged deferral of antiretroviral therapy in the SAPIT trial: Did we need a clinical trial to tell us that this would increase mortality? South African Medical Journal 2010, 100: 566,568,570-571. PMID: 20822639, DOI: 10.7196/samj.4434.Peer-Reviewed Original Research