2022
Neighbourhood prevalence-to-notification ratios for adult bacteriologically-confirmed tuberculosis reveals hotspots of underdiagnosis in Blantyre, Malawi
Khundi M, Carpenter JR, Corbett EL, Feasey HRA, Soko RN, Nliwasa M, Twabi H, Chiume L, Burke RM, Horton KC, Dodd PJ, Cohen T, MacPherson P. Neighbourhood prevalence-to-notification ratios for adult bacteriologically-confirmed tuberculosis reveals hotspots of underdiagnosis in Blantyre, Malawi. PLOS ONE 2022, 17: e0268749. PMID: 35605004, PMCID: PMC9126376, DOI: 10.1371/journal.pone.0268749.Peer-Reviewed Original ResearchConceptsCase notification ratesPrevalence surveyNotification ratioNeighbourhood prevalenceTB case notification ratesXpert MTB/RIFCase-finding interventionsTrue disease burdenChest X-ray screeningTB prevalence surveyTB surveillance systemMTB/RIFDiagnosis of tuberculosisSputum smear microscopyTB clinicTB patientsRespiratory infectionsTB prevalenceDisease burdenNotification ratesSmear microscopyX-ray screeningTuberculosisPrevalenceUrban tuberculosis
2019
Disparities in access to diagnosis and care in Blantyre, Malawi, identified through enhanced tuberculosis surveillance and spatial analysis
MacPherson P, Khundi M, Nliwasa M, Choko AT, Phiri VK, Webb EL, Dodd PJ, Cohen T, Harris R, Corbett EL. Disparities in access to diagnosis and care in Blantyre, Malawi, identified through enhanced tuberculosis surveillance and spatial analysis. BMC Medicine 2019, 17: 21. PMID: 30691470, PMCID: PMC6350280, DOI: 10.1186/s12916-019-1260-6.Peer-Reviewed Original ResearchConceptsTB case notification ratesCase notification ratesCommunity health workersNotification ratesTB casesLow case detectionSingle sputum sampleInverse care lawArea-level factorsTB registrationTB clinicTB patientsClinical characteristicsTB diagnosisTuberculosis casesResultsIn totalTB surveillanceCase detectionModifiable predictorsSputum samplesHealth workersTB officersTB microscopyAdjusted modelTuberculosis surveillance