The interrelationship of body mass index with gray matter volume and resting-state functional connectivity of the hypothalamus
Le TM, Liao DL, Ide J, Zhang S, Zhornitsky S, Wang W, Li CR. The interrelationship of body mass index with gray matter volume and resting-state functional connectivity of the hypothalamus. International Journal Of Obesity 2019, 44: 1097-1107. PMID: 31796869, PMCID: PMC8643195, DOI: 10.1038/s41366-019-0496-8.Peer-Reviewed Original ResearchConceptsResting-state functional connectivityWhole-brain multiple regressionGray matter volumeInsula connectivityBody mass indexFunctional connectivitySeed-based resting-state functional connectivityMatter volumeSuperior parietal lobuleVoxel-based morphometry analysisMultiple regressionConclusionsThe current findingsBody weightCognitive controlMultiple brain circuitsBrain mechanismsIndividual differencesInhibitory controlParietal lobuleHypothalamic connectivityMass indexMediation analysisBrain circuitsHigher body mass indexCurrent findingsProblem drinking alters gray matter volume and food cue responses of the lateral orbitofrontal cortex
Le TM, Zhornitsky S, Wang W, Zhang S, Li C. Problem drinking alters gray matter volume and food cue responses of the lateral orbitofrontal cortex. Addiction Biology 2019, 26: e12857. PMID: 31746092, PMCID: PMC8627684, DOI: 10.1111/adb.12857.Peer-Reviewed Original ResearchConceptsLateral orbitofrontal cortexAlcohol Use Disorders Identification TestGray matter volumeEffect of ProblemOrbitofrontal cortexWhole-brain multiple regressionLeft middle frontal gyrusAlcohol misuseFood cue responsesFunctional magnetic resonance imaging (fMRI) dataVisual food cuesAUDIT scoresMatter volumeMiddle frontal gyrusAffective processesNonfood cuesFood cuesNonfood imagesBrain substratesDisorders Identification TestFrontal gyrusNeural mechanismsFood stimuliCue responsesFood images