2018
Comparative Analysis of Zearalenone Effects on Thyroid Receptor Alpha (TRα) and Beta (TRβ) Expression in Rat Primary Cerebellar Cell Cultures
Kiss DS, Ioja E, Toth I, Barany Z, Jocsak G, Bartha T, Horvath TL, Zsarnovszky A. Comparative Analysis of Zearalenone Effects on Thyroid Receptor Alpha (TRα) and Beta (TRβ) Expression in Rat Primary Cerebellar Cell Cultures. International Journal Of Molecular Sciences 2018, 19: 1440. PMID: 29751674, PMCID: PMC5983839, DOI: 10.3390/ijms19051440.Peer-Reviewed Original ResearchConceptsQuantitative reverse transcription polymerase chain reactionThyroid hormonesExpression levelsAbsence of gliaExpression of TRsReverse transcription-polymerase chain reactionThyroid receptor alphaTranscription-polymerase chain reactionPrimary cerebellar neuronsPrimary cerebellar granule cellsPrimary cerebellar cell culturesPostnatal brain developmentCerebellar granule cellsSerious health problemCerebellar cell culturesHormonal milieuGlial cellsBeta expressionGranule cellsReceptor alphaReceptor αThyroid receptor αHealth problemsLow dosesCerebellar neurons
2008
Exercise-Induced Synaptogenesis in the Hippocampus Is Dependent on UCP2-Regulated Mitochondrial Adaptation
Dietrich MO, Andrews ZB, Horvath TL. Exercise-Induced Synaptogenesis in the Hippocampus Is Dependent on UCP2-Regulated Mitochondrial Adaptation. Journal Of Neuroscience 2008, 28: 10766-10771. PMID: 18923051, PMCID: PMC3865437, DOI: 10.1523/jneurosci.2744-08.2008.Peer-Reviewed Original ResearchConceptsSynaptic plasticityVoluntary exerciseEssential organellesUCP2 functionProtein-2 mRNA expressionDendritic spine synapsesBioenergetic adaptationMitochondrial metabolismMitochondrial oxygen consumptionMitochondrial numberEnergetic needsMitochondrial adaptationsMitochondrial mechanismsExercise inducesDentate gyrusStratum radiatumSpine synapsesCA1 regionGlial morphologyHippocampal formationNeuronal activityGranule cellsAction potentialsNeuronal morphologyMRNA expression