The Predictive Role of Model for End‐Stage Liver Disease–Lactate and Lactate Clearance for In‐Hospital Mortality Among a National Cirrhosis Cohort
Mahmud N, Asrani SK, Kaplan DE, Ogola GO, Taddei TH, Kamath PS, Serper M. The Predictive Role of Model for End‐Stage Liver Disease–Lactate and Lactate Clearance for In‐Hospital Mortality Among a National Cirrhosis Cohort. Liver Transplantation 2021, 27: 177-189. PMID: 33025731, PMCID: PMC7880877, DOI: 10.1002/lt.25913.Peer-Reviewed Original ResearchConceptsEnd-stage liver diseaseHospital mortalityLactate clearanceCirrhosis hospitalizationsMELD-NaLiver diseaseDay 1Predictive roleRetrospective cohort studyIn-Hospital MortalityRisk-stratify patientsVeterans Health AdministrationCirrhosis cohortMELD categoriesGastrointestinal bleedingCohort studyClinical dataLimited cohortStratified analysisLactate levelsHospitalizationHealth AdministrationMELDClinical toolMortalityPatient Frailty Is Independently Associated With the Risk of Hospitalization for Acute‐on‐Chronic Liver Failure
Shah S, Goldberg DS, Kaplan DE, Sundaram V, Taddei TH, Mahmud N. Patient Frailty Is Independently Associated With the Risk of Hospitalization for Acute‐on‐Chronic Liver Failure. Liver Transplantation 2021, 27: 16-26. PMID: 32946660, PMCID: PMC8249075, DOI: 10.1002/lt.25896.Peer-Reviewed Original ResearchConceptsChronic liver failureFrailty scoreACLF mortalityPatient frailtyLiver failureLongterm survivalPoorer longterm survivalImpact of frailtyRisk of hospitalizationTime of hospitalizationWait-list mortalityACLF developmentCirrhosis hospitalizationsFrail outpatientsTransplant evaluationFirst hospitalizationPosttransplant outcomesTransplant candidatesCox analysisRetrospective studyCox regressionUS veteransRisk factorsHospitalizationAdjusted model