2019
Sequel and therapeutic modalities of leptospirosis associated severe pulmonary haemorrhagic syndrome (SPHS); a Sri Lankan experience
Herath N, Uluwattage W, Weliwitiya T, Karunanayake L, Lekamwasam S, Ratnatunga N, Karunanayake P, Wickramasinghe S, Patabendi S, Senaviratne S, Agampodi S. Sequel and therapeutic modalities of leptospirosis associated severe pulmonary haemorrhagic syndrome (SPHS); a Sri Lankan experience. BMC Infectious Diseases 2019, 19: 451. PMID: 31113404, PMCID: PMC6530063, DOI: 10.1186/s12879-019-4094-0.Peer-Reviewed Original ResearchConceptsTeaching Hospital KarapitiyaTherapeutic plasma exchangeAcute kidney injuryMain tertiary care centerSevere pulmonary hemorrhagic syndromeTertiary care centerDay of admissionGroup of patientsHigh case fatalityCase fatality rateCases of leptospirosisDifferent therapeutic approachesAlveolar shadowsHospital KarapitiyaHemoglobin dropKidney injuryArterial hypoxemiaCase fatalityPlasma exchangePatient presentingTreatment modalitiesCare centerHemorrhagic syndromeChest radiographsClinical disease
2016
From organophosphate poisoning to diabetes mellitus: The incretin effect
Rathish D, Agampodi SB, Jayasumana MACS, Siribaddana SH. From organophosphate poisoning to diabetes mellitus: The incretin effect. Medical Hypotheses 2016, 91: 53-55. PMID: 27142144, DOI: 10.1016/j.mehy.2016.04.002.Peer-Reviewed Original ResearchConceptsAccumulation of acetylcholineIncretin effectGlucose homeostasisDiabetes mellitusOP poisoningType 2 diabetes mellitusPeptide-1 secretionAcute OPMuscarinic receptorsTreatment modalitiesOrganophosphate poisoningPositive findingsInhibition of acetylcholinesterasesMellitusInduced disruptionHomeostasisPoisoningInhibitionDisruptionT2DMAcetylcholineGlucagonIncidenceSecretionReceptors