2021
Preoperative risk and postoperative outcome from subdural fluid collections in African infants with postinfectious hydrocephalus.
Lane J, Ssentongo P, Peterson M, Harper J, Mbabazi-Kabachelor E, Mugamba J, Ssenyonga P, Onen J, Donnelly R, Levenbach J, Cherukuri V, Monga V, Kulkarni A, Warf B, Schiff S. Preoperative risk and postoperative outcome from subdural fluid collections in African infants with postinfectious hydrocephalus. Journal Of Neurosurgery Pediatrics 2021, 29: 31-39. PMID: 34598146, PMCID: PMC9078082, DOI: 10.3171/2021.7.peds21209.Peer-Reviewed Original Research
2019
The Incidence of Postoperative Seizures Following Treatment of Postinfectious Hydrocephalus in Ugandan Infants: A Post Hoc Comparison of Endoscopic Treatment vs Shunt Placement in a Randomized Controlled Trial.
Punchak M, Mbabazi Kabachelor E, Ogwal M, Nalule E, Nalwoga J, Ssenyonga P, Mugamba J, Rattani A, Dewan M, Kulkarni A, Schiff S, Warf B. The Incidence of Postoperative Seizures Following Treatment of Postinfectious Hydrocephalus in Ugandan Infants: A Post Hoc Comparison of Endoscopic Treatment vs Shunt Placement in a Randomized Controlled Trial. Neurosurgery 2019, 85: e714-e721. PMID: 31086941, PMCID: PMC7534394, DOI: 10.1093/neuros/nyz122.Peer-Reviewed Original ResearchConceptsChoroid plexus cauterizationETV/CPCPostoperative seizure incidencePostinfectious hydrocephalusSeizure incidenceEndoscopic third ventriculostomyUgandan infantsShunt placementMantel-Haenszel hazard ratiosKaplan-Meier methodVentriculoperitoneal shunt placementPostoperative epilepsyPostoperative seizuresPreoperative symptomsEpilepsy incidenceFirst seizureHazard ratioControlled TrialsEndoscopic treatmentThird ventriculostomyTreatment modalitiesSeizure riskHead circumferenceRelative riskSeizure onset
2014
Volumetric brain analysis in neurosurgery: Part 3. Volumetric CT analysis as a predictor of seizure outcome following temporal lobectomy.
Mandell J, Hill K, Nguyen D, Moser K, Harbaugh R, McInerney J, Nsubuga B, Mugamba J, Johnson D, Warf B, Boling W, Webb A, Schiff S. Volumetric brain analysis in neurosurgery: Part 3. Volumetric CT analysis as a predictor of seizure outcome following temporal lobectomy. Journal Of Neurosurgery Pediatrics 2014, 15: 133-43. PMID: 25431899, DOI: 10.3171/2014.9.peds12428.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnterior Temporal LobectomyBrainCerebrospinal FluidChildChild, PreschoolCognitionCone-Beam Computed TomographyEpilepsy, Temporal LobeFemaleFrontal LobeHumansHydrocephalusInfantMagnetic Resonance ImagingMaleNeurosurgical ProceduresOccipital LobeOrgan SizePredictive Value of TestsSeizuresTreatment OutcomeUgandaConceptsTemporal lobe volumeMesial temporal sclerosisTemporal lobe epilepsyTemporal lobe resectionSeizure outcomeTemporal lobeVolumetric CT analysisBrain volumeLobe volumeSeizure controlStructural MRILobe resectionEngel class Ia outcomeClass Ia outcomeSelection of patientsCT volumetric analysisPreoperative CT scanSmaller brain volumesSmaller temporal lobeCURE Children's HospitalIncomplete seizure controlNormalized brain volumeWhole brain volumeCT analysisTemporal lobe structuresVolumetric brain analysis in neurosurgery: Part 2. Brain and CSF volumes discriminate neurocognitive outcomes in hydrocephalus.
Mandell J, Kulkarni A, Warf B, Schiff S. Volumetric brain analysis in neurosurgery: Part 2. Brain and CSF volumes discriminate neurocognitive outcomes in hydrocephalus. Journal Of Neurosurgery Pediatrics 2014, 15: 125-32. PMID: 25431901, DOI: 10.3171/2014.9.peds12427.Peer-Reviewed Original ResearchConceptsFrontal-occipital horn ratioNeurocognitive outcomesBrain volumeCSF volumeFluid volumePediatric patientsBrain developmentEvaluation of hydrocephalusGoal of treatmentSmaller brain volumesLower cognitive outcomesPoor neurocognitive outcomesNormal brain developmentLarge fluid volumesHealthy brain developmentVolumetric brain analysisSurgical treatmentVentricular sizeHydrocephalic patientsCT scanHydrocephalusPatientsBayley ScalesBrain growthFine motor
2011
Costs and benefits of neurosurgical intervention for infant hydrocephalus in sub-Saharan Africa.
Warf B, Alkire B, Bhai S, Hughes C, Schiff S, Vincent J, Meara J. Costs and benefits of neurosurgical intervention for infant hydrocephalus in sub-Saharan Africa. Journal Of Neurosurgery Pediatrics 2011, 8: 509-21. PMID: 22044378, DOI: 10.3171/2011.8.peds11163.Peer-Reviewed Original ResearchConceptsBenefit-cost ratioDisability-adjusted life yearsHuman capital approachEconomic benefitsNeurosurgical interventionCapital approachCost/disability-adjusted life yearStatistical life approachFavorable benefit-cost ratioTotal economic benefitPotential economic impactMajor public health priorityEndoscopic third ventriculostomyBenefits of treatmentCases of hydrocephalusVSL approachPublic health priorityEconomic modelingCURE Children's HospitalTreatment of hydrocephalusEconomic impactLife yearsUntreated hydrocephalusRetrospective reviewShunt placementFive-year survival and outcome of treatment for postinfectious hydrocephalus in Ugandan infants.
Warf B, Dagi A, Kaaya B, Schiff S. Five-year survival and outcome of treatment for postinfectious hydrocephalus in Ugandan infants. Journal Of Neurosurgery Pediatrics 2011, 8: 502-8. PMID: 22044377, DOI: 10.3171/2011.8.peds11221.Peer-Reviewed Original ResearchConceptsPostinfectious hydrocephalusFive-year survivalShunt placementPrimary brain injuryWorse functional outcomeKaplan-Meier methodLong-term outcomesLog-rank testOutcome of treatmentEndoscopic third ventriculostomyTreatment selection biasPublic health measuresOne-thirdUgandan infantsWorst sequelaeOperative mortalityNeonatal infectionFunctional outcomeThird ventriculostomyBrain injuryPrimary treatmentCommon causeInfant hydrocephalusSurvival advantageOriginal infection
1995
FDG-PET in children and adolescents with partial seizures: Role in epilepsy surgery,evaluation
Gaillard W, White S, MalOw B, Flamini R, Weinstein S, Sato S, Kufta C, Schiff S, Devinsky O, Fazilat S, Reeves P, Theodore W. FDG-PET in children and adolescents with partial seizures: Role in epilepsy surgery,evaluation. Epilepsy Research 1995, 20: 77-84. PMID: 7713062, DOI: 10.1016/0920-1211(94)00065-5.Peer-Reviewed Original ResearchConceptsComplex partial seizuresEEG fociPartial seizuresFDG-PETEpileptic focusGlucose metabolismRefractory complex partial epilepsyFocal MRI abnormalitiesInterictal glucose metabolismUnilateral EEG focusFDG-PET resultsFDG-PET hypometabolismComplex partial epilepsyFocal hypometabolismPET hypometabolismMRI abnormalitiesMetabolic abnormalitiesEpilepsy surgerySurgical interventionPartial epilepsyVideo-EEGEpileptogenic zonePoor responseRegional hypometabolismDrug treatment
1994
Time-related patterns of ventricular shunt failure
Kast J, Duong D, Nowzari F, Chadduck W, Schiff S. Time-related patterns of ventricular shunt failure. Child's Nervous System 1994, 10: 524-528. PMID: 7882375, DOI: 10.1007/bf00335075.Peer-Reviewed Original ResearchConceptsShunt failureVentricular shunt failureVentriculoperitoneal shunt failureAge of patientsCatheter placement techniqueVentricular catheter placementNovel valve systemDistal failureDistal malfunctionProximal malfunctionConsecutive patientsProximal obstructionShunt placementCatheter placementPrimary etiologyShunt revisionShunt malfunctionSite of failureTime-related patternOverall seriesProximal failureCommon causeOutcome studiesHigh incidencePatients