2023
Identification of White Matter Hyperintensities in Routine Emergency Department Visits Using Portable Bedside Magnetic Resonance Imaging
de Havenon A, Parasuram N, Crawford A, Mazurek M, Chavva I, Yadlapalli V, Iglesias J, Rosen M, Falcone G, Payabvash S, Sze G, Sharma R, Schiff S, Safdar B, Wira C, Kimberly W, Sheth K. Identification of White Matter Hyperintensities in Routine Emergency Department Visits Using Portable Bedside Magnetic Resonance Imaging. Journal Of The American Heart Association 2023, 12: e029242. PMID: 37218590, PMCID: PMC10381997, DOI: 10.1161/jaha.122.029242.Peer-Reviewed Original ResearchConceptsWhite matter hyperintensitiesMagnetic resonance imagingSevere white matter hyperintensitiesConventional magnetic resonance imagingResonance imagingRetrospective cohortEmergency departmentMatter hyperintensitiesVascular risk factorsProspective observational studyVascular cognitive impairmentTesla magnetic resonance imagingArea Deprivation IndexProspective cohortAdult patientsAcute careRisk factorsCardiovascular diseaseObservational studyCognitive impairmentPatientsCare magnetic resonance imagingIntermodality agreementCohortDeprivation index
2022
Cytomegalovirus infections in infants in Uganda: Newborn-mother pairs, neonates with sepsis, and infants with hydrocephalus
Hehnly C, Ssentongo P, Bebell L, Burgoine K, Bazira J, Fronterre C, Kumbakumba E, Mulondo R, Mbabazi-Kabachelor E, Morton S, Ngonzi J, Ochora M, Olupot-Olupot P, Mugamba J, Onen J, Roberts D, Sheldon K, Sinnar S, Smith J, Ssenyonga P, Kiwanuka J, Paulson J, Meier F, Ericson J, Broach J, Schiff S. Cytomegalovirus infections in infants in Uganda: Newborn-mother pairs, neonates with sepsis, and infants with hydrocephalus. International Journal Of Infectious Diseases 2022, 118: 24-33. PMID: 35150915, PMCID: PMC9058984, DOI: 10.1016/j.ijid.2022.02.005.Peer-Reviewed Original ResearchConceptsNewborn-mother pairsCMV prevalenceClinical sepsisCytomegalovirus infectionCerebrospinal fluidPrevalence of CMVQuantitative PCRCMV positivityPostinfectious hydrocephalusVaginal sheddingCMV infectionHIV seropositivityNeonatal ageMaternal ageMaternal vaginalRisk factorsMedical CenterLong-term consequencesMother pairsSepsisNeonatesInfantsPrevalenceHydrocephalusCMV
2021
Congenital Cytomegalovirus Infection Burden and Epidemiologic Risk Factors in Countries With Universal Screening
Ssentongo P, Hehnly C, Birungi P, Roach M, Spady J, Fronterre C, Wang M, Murray-Kolb L, Al-Shaar L, Chinchilli V, Broach J, Ericson J, Schiff S. Congenital Cytomegalovirus Infection Burden and Epidemiologic Risk Factors in Countries With Universal Screening. JAMA Network Open 2021, 4: e2120736. PMID: 34424308, PMCID: PMC8383138, DOI: 10.1001/jamanetworkopen.2021.20736.Peer-Reviewed Original ResearchConceptsPrevalence of cCMVHigh-income countriesBirth prevalenceUniversal screeningInfection burdenHIV prevalenceRisk factorsBlood samplesCommon congenital infectionMaternal CMV seroprevalenceCongenital cytomegalovirus infectionEpidemiologic risk factorsPooled overall prevalenceNewcastle-Ottawa ScaleSystematic Reviews databasesMeta-Analyses (PRISMA) guidelinesPooled birth prevalenceMEDLINE/PubMedPreferred Reporting ItemsLow socioeconomic statusWorld Bank income levelsLower ratesCMV seroprevalenceCongenital infectionCohort study
2020
Micronutrient Supplementation During Pregnancy, Birth Weight and Neonatal Mortality in Uganda: A Causal Mediation Analysis
Ssentongo P, Ba D, Fronterre C, Ericson J, Gernand A, Wang M, Du P, Liao D, Chinchilli V, Schiff S. Micronutrient Supplementation During Pregnancy, Birth Weight and Neonatal Mortality in Uganda: A Causal Mediation Analysis. Current Developments In Nutrition 2020, 4: nzaa053_117. PMCID: PMC7257698, DOI: 10.1093/cdn/nzaa053_117.Peer-Reviewed Original ResearchLow birth weightIFA supplementationNeonatal mortalityBirth weightCausal mediation analysisIron/folic acid supplementsRisk of LBWPrevalence of LBWMaternal iron deficiency anemiaAntenatal IFA supplementationFolic acid supplementsSignificant risk factorsIron deficiency anemiaRetrospective birth cohortLinear dose-response relationshipDays of lifeRisk of VLBWDose-response relationshipIFA supplementsTerm infantsNeonatal deathMicronutrient supplementationRisk factorsHealth SurveyNeonatal survival