2022
Increasing angular sampling through deep learning for stationary cardiac SPECT image reconstruction
Xie H, Thorn S, Chen X, Zhou B, Liu H, Liu Z, Lee S, Wang G, Liu YH, Sinusas AJ, Liu C. Increasing angular sampling through deep learning for stationary cardiac SPECT image reconstruction. Journal Of Nuclear Cardiology 2022, 30: 86-100. PMID: 35508796, DOI: 10.1007/s12350-022-02972-z.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDeep LearningHumansImage Processing, Computer-AssistedPhantoms, ImagingSwineTomography, Emission-Computed, Single-PhotonTomography, X-Ray ComputedConceptsDeep learningReconstruction qualityImage reconstructionDeep learning methodsDeep neural networksDeep learning resultsImage qualityNetwork trainingSPECT image reconstructionNeural networkLearning methodsHigh image resolutionImage volumesClinical softwareImage metricsImage resolutionReconstruction resultsImproved image qualityTesting dataLearning resultsNetwork resultsPhysical phantomStationary imagingDifferent subjectsLearning
2020
Quantification of myocardial blood flow (MBF) and reserve (MFR) incorporated with a novel segmentation approach: Assessments of quantitative precision and the lower limit of normal MBF and MFR in patients
Liu H, Thorn S, Wu J, Fazzone-Chettiar R, Sandoval V, Miller EJ, Sinusas AJ, Liu YH. Quantification of myocardial blood flow (MBF) and reserve (MFR) incorporated with a novel segmentation approach: Assessments of quantitative precision and the lower limit of normal MBF and MFR in patients. Journal Of Nuclear Cardiology 2020, 28: 1236-1248. PMID: 32715416, DOI: 10.1007/s12350-020-02278-y.Peer-Reviewed Original Research
2019
A robust segmentation method with triple‐factor non‐negative matrix factorization for myocardial blood flow quantification from dynamic 82Rb positron emission tomography
Liu H, Wu J, Sun J, Wu T, Fazzone‐Chettiar R, Thorn S, Sinusas AJ, Liu Y. A robust segmentation method with triple‐factor non‐negative matrix factorization for myocardial blood flow quantification from dynamic 82Rb positron emission tomography. Medical Physics 2019, 46: 5002-5013. PMID: 31444909, DOI: 10.1002/mp.13783.Peer-Reviewed Original ResearchCoronary CirculationFeasibility StudiesHeart VentriclesHumansImage Processing, Computer-AssistedPositron-Emission TomographyRubidium RadioisotopesDirect List Mode Parametric Reconstruction for Dynamic Cardiac SPECT
Shi L, Lu Y, Wu J, Gallezot JD, Boutagy N, Thorn S, Sinusas AJ, Carson RE, Liu C. Direct List Mode Parametric Reconstruction for Dynamic Cardiac SPECT. IEEE Transactions On Medical Imaging 2019, 39: 119-128. PMID: 31180845, PMCID: PMC7030971, DOI: 10.1109/tmi.2019.2921969.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsAnimalsCardiac Imaging TechniquesComputer SimulationDogsHeartImage Processing, Computer-AssistedPhantoms, ImagingTomography, Emission-Computed, Single-PhotonConceptsAppropriate kinetic modelConventional indirect methodImage reconstruction algorithmKinetic modelHigh noise levelsLow count levelsVivo canine studyIndirect methodImage noiseNoise levelParametric reconstructionNoiseReconstruction algorithmFrame imagePatient radiation dose reductionMethodDirect methodLower image noise
2018
Simplified Quantification and Acquisition Protocol for 123I-MIBG Dynamic SPECT
Wu J, Gallezot JD, Lu Y, Ye Q, Liu H, Esserman DA, Kyriakides TC, Thorn S, Zonouz TH, Liu YH, Lampert R, Sinusas AJ, Carson RE, Liu C. Simplified Quantification and Acquisition Protocol for 123I-MIBG Dynamic SPECT. Journal Of Nuclear Medicine 2018, 59: 1574-1580. PMID: 29476001, DOI: 10.2967/jnumed.117.202143.Peer-Reviewed Original Research3-IodobenzylguanidineFemaleHealthy VolunteersHumansImage Processing, Computer-AssistedKineticsMaleMiddle AgedTomography, Emission-Computed, Single-Photon
2012
A three-dimensional model-based partial volume correction strategy for gated cardiac mouse PET imaging
Dumouchel T, Thorn S, Kordos M, DaSilva J, Beanlands RS, deKemp RA. A three-dimensional model-based partial volume correction strategy for gated cardiac mouse PET imaging. Physics In Medicine And Biology 2012, 57: 4309-4334. PMID: 22705820, DOI: 10.1088/0031-9155/57/13/4309.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsAnimalsCardiac-Gated Imaging TechniquesElectrocardiographyHeart VentriclesImage Processing, Computer-AssistedMiceModels, BiologicalMovementPhantoms, ImagingPositron-Emission Tomography