Reductions in World Health Organization Risk Drinking Level Are Associated With Reductions in Alcohol Use Disorder Diagnosis and Criteria: Evidence From an Alcohol Pharmacotherapy Trial
Richards D, Tuchman F, Hallgren K, Kranzler H, Aubin H, O'Malley S, Mann K, Aldridge A, Anton R, Witkiewitz K. Reductions in World Health Organization Risk Drinking Level Are Associated With Reductions in Alcohol Use Disorder Diagnosis and Criteria: Evidence From an Alcohol Pharmacotherapy Trial. Journal Of Addiction Medicine 2024, 18: 418-424. PMID: 38606854, PMCID: PMC11290995, DOI: 10.1097/adm.0000000000001303.Peer-Reviewed Original ResearchConceptsWorld Health Organization risk drinking levelsAlcohol use disorderAlcohol use disorder diagnosisAlcohol use disorder criteriaDrinking levelsMini International Neuropsychiatric InterviewSevere alcohol use disorderCurrent alcohol use disorderGabapentin enacarbilRisk drinking levelsMultisite randomized controlled trialAlcohol intervention trialPharmacotherapy trialsAUD diagnosisAUD treatmentNeuropsychiatric InterviewBaseline to endDisorder diagnosisEnd of treatmentFollow-backUse disorderAssess DiagnosticWorld Health OrganizationAssociated with reductionsSecondary data analysisReductions in WHO risk drinking levels correlate with alcohol craving among individuals with alcohol use disorder
Tuchman F, Hallgren K, Richards D, Aldridge A, Anton R, Aubin H, Kranzler H, Mann K, O'Malley S, Witkiewitz K. Reductions in WHO risk drinking levels correlate with alcohol craving among individuals with alcohol use disorder. Alcohol Clinical And Experimental Research 2024, 48: 420-429. PMID: 38149364, PMCID: PMC10922776, DOI: 10.1111/acer.15257.Peer-Reviewed Original ResearchWorld Health Organization risk drinking levelsAlcohol use disorderAlcohol use disorder severityDrinking reductionDrinking levelsAlcohol cravingUse disorderAlcohol use disorder treatmentAssociated with lower cravingRisk drinking levelsSelf-report measuresEnd-of-treatmentCraving reductionLower cravingCravingModeration analysisWorld Health OrganizationBehavioral interventionsSecondary analysis of dataAssociated with reductionsClinical trial endpointsDisordersSecondary analysisAlcoholDrinking