Design of Hydrazide-Bearing HDACIs Based on Panobinostat and Their p53 and FLT3-ITD Dependency in Antileukemia Activity
Li X, Jiang Y, Peterson YK, Xu T, Himes RA, Luo X, Yin G, Inks ES, Dolloff N, Halene S, Chan SSL, Chou CJ. Design of Hydrazide-Bearing HDACIs Based on Panobinostat and Their p53 and FLT3-ITD Dependency in Antileukemia Activity. Journal Of Medicinal Chemistry 2020, 63: 5501-5525. PMID: 32321249, PMCID: PMC7684764, DOI: 10.1021/acs.jmedchem.0c00442.Peer-Reviewed Original Research