In vivo evaluation of a neural stem cell-seeded prosthesis
Purcell E, Seymour J, Yandamuri S, Kipke D. In vivo evaluation of a neural stem cell-seeded prosthesis. Journal Of Neural Engineering 2009, 6: 026005. PMID: 19287078, PMCID: PMC2930820, DOI: 10.1088/1741-2560/6/2/026005.Peer-Reviewed Original ResearchConceptsNeuronal lossGlial encapsulationNeural stem cellsNeurotrophic factorSensory deficitsGraft cellsNeuronal activityChronic applicationBrain tissueHealing responseSubsequent cell deathDegenerative diseasesSynthetic prosthesesTime pointsProgenitor cellsInitial weeksVivo evaluationReactive tissue responseTissue responseCell deathStem cellsWeeksProsthesisImplantationCells