Putamen volume and its clinical and neurological correlates in primary HIV infection
Wright PW, Pyakurel A, Vaida FF, Price RW, Lee E, Peterson J, Fuchs D, Zetterberg H, Robertson KR, Walter R, Meyerhoff DJ, Spudich SS, Ances BM. Putamen volume and its clinical and neurological correlates in primary HIV infection. AIDS 2016, 30: 1789-1794. PMID: 27045376, PMCID: PMC4925211, DOI: 10.1097/qad.0000000000001103.Peer-Reviewed Original ResearchConceptsEarly HIV infectionHIV infectionPutamen volumeCerebrospinal fluidCD4/CD8 ratioCentral nervous system changesCross-sectional neuroimaging studiesTrajectory of HIVCD4 cell countPrimary HIV infectionCortical white matterTotal gray matterNervous system changesEarly HIVFreeSurfer 5.1CD8 ratioT1 MRI scansNeuropsychometric testsNatural coursePHI groupCorpus callosumInterventional strategiesInfection durationNeuropsychological testingVolumetric alterations