2016
UCP2 Regulates Mitochondrial Fission and Ventromedial Nucleus Control of Glucose Responsiveness
Toda C, Kim JD, Impellizzeri D, Cuzzocrea S, Liu ZW, Diano S. UCP2 Regulates Mitochondrial Fission and Ventromedial Nucleus Control of Glucose Responsiveness. Cell 2016, 164: 872-883. PMID: 26919426, PMCID: PMC4770556, DOI: 10.1016/j.cell.2016.02.010.Peer-Reviewed Original ResearchConceptsSystemic glucose homeostasisMitochondrial fissionCellular biological processesMitochondrial dynamicsGenetic manipulationGlucose homeostasisReactive oxygen speciesBiological processesMitochondrial adaptationsProtein 2Reduced reactive oxygen speciesOxygen speciesHomeostasisCritical roleMetabolic environmentGlucose-excited neuronsGlucose responsivenessFissionNeuronal circuitrySpeciesNeuronsRegulationVMH neuronsGlucose loadPool
2001
Minireview: Ghrelin and the Regulation of Energy Balance—A Hypothalamic Perspective
Horvath T, Diano S, Sotonyi P, Heiman M, Tschöp M. Minireview: Ghrelin and the Regulation of Energy Balance—A Hypothalamic Perspective. Endocrinology 2001, 142: 4163-4169. DOI: 10.1210/en.142.10.4163.Peer-Reviewed Original ResearchGH secretionSynthetic ghrelin receptor agonistRegulation of GH secretionGhrelin receptor agonistEtiology of obesityEnergy homeostasisRegulate energy homeostasisGH secretagoguesReceptor agonistsLeptin actionClinical trialsGhrelinChronic changesNeuroendocrine networkPrevent energy deficitRegulation of metabolismNutritional stateCentral regulatorCentral regulator of metabolismSubject of ongoing discussionsRegulation of growth processesEnergy deficitSecretionHomeostasisStomach