2011
Methicillin-Resistant Staphylococcus aureus Infection and Hospitalization in High-Risk Patients in the Year following Detection
Huang SS, Hinrichsen VL, Datta R, Spurchise L, Miroshnik I, Nelson K, Platt R. Methicillin-Resistant Staphylococcus aureus Infection and Hospitalization in High-Risk Patients in the Year following Detection. PLOS ONE 2011, 6: e24340. PMID: 21949707, PMCID: PMC3174953, DOI: 10.1371/journal.pone.0024340.Peer-Reviewed Original ResearchConceptsMethicillin-resistant Staphylococcus aureus (MRSA) infectionsPost-discharge infectionsStaphylococcus aureus infectionMRSA infectionHealthcare utilizationAureus infectionTertiary care medical centerPrimary bloodstream infectionsRetrospective cohort studyHigh-risk patientsTertiary care patientsHarvard Pilgrim Health CareSubstantial attributable mortalitySingle hospitalizationMRSA carriageMRSA carriersAdult patientsCohort studyHospital dischargeSubsequent readmissionCare patientsAttributable mortalityBloodstream infectionsCommon infectionsMost infectionsColonization with antibiotic-susceptible strains protects against methicillin-resistant Staphylococcus aureus but not vancomycin-resistant enterococci acquisition: a nested case-control study
Huang SS, Datta R, Rifas-Shiman S, Kleinman K, Placzek H, Lankiewicz JD, Platt R. Colonization with antibiotic-susceptible strains protects against methicillin-resistant Staphylococcus aureus but not vancomycin-resistant enterococci acquisition: a nested case-control study. Critical Care 2011, 15: r210. PMID: 21914221, PMCID: PMC3334754, DOI: 10.1186/cc10445.Peer-Reviewed Original ResearchConceptsMethicillin-resistant Staphylococcus aureusMethicillin-sensitive Staphylococcus aureusVancomycin-resistant enterococciInitial negative swabCase-control studyVancomycin-sensitive enterococciMRSA acquisitionVRE acquisitionICU admissionRisk factorsNegative swabsStaphylococcus aureusHigh endemic settingMRSA-positive patientsVancomycin-resistant enterococci acquisitionThird-generation cephalosporinsSensitive strainsPredictors of acquisitionBilateral naresMSSA carriageMSSA infectionsSame hospitalizationICU patientsLow albuminMRSA infection
2008
Risk of Infection and Death due to Methicillin- Resistant Staphylococcus aureus in Long-Term Carriers
Datta R, Huang SS. Risk of Infection and Death due to Methicillin- Resistant Staphylococcus aureus in Long-Term Carriers. Clinical Infectious Diseases 2008, 47: 176-181. PMID: 18532892, PMCID: PMC2649874, DOI: 10.1086/589241.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overBacteremiaBostonCarrier StateCatheterization, Central VenousCohort StudiesFemaleHospitalizationHumansLogistic ModelsMaleMethicillin ResistanceMiddle AgedPneumoniaRetrospective StudiesRisk FactorsSex FactorsSoft Tissue InfectionsStaphylococcal InfectionsStaphylococcus aureusTime FactorsConceptsMethicillin-resistant Staphylococcus aureusLong-term carriersRisk of infectionMRSA infectionSingle-center retrospective cohort studyCentral venous catheter infectionSubsequent MRSA infectionVenous catheter infectionRetrospective cohort studyShort-term morbiditySoft tissue infectionsDuration of carriageStaphylococcus aureusMRSA colonizationCohort studyCatheter infectionCommon infectionsNew hospitalizationHigh riskSubsequent infectionTime of detectionPersistent riskInfectionSignificant riskDeathStrain-Relatedness of Methicillin- Resistant Staphylococcus aureus Isolates Recovered from Patients with Repeated Infection
Huang SS, Diekema DJ, Warren DK, Zuccotti G, Winokur PL, Tendolkar S, Boyken L, Datta R, Jones RM, Ward MA, Aubrey T, Onderdonk AB, Garcia C, Platt R. Strain-Relatedness of Methicillin- Resistant Staphylococcus aureus Isolates Recovered from Patients with Repeated Infection. Clinical Infectious Diseases 2008, 46: 1241-1247. PMID: 18444862, PMCID: PMC2723744, DOI: 10.1086/529381.Peer-Reviewed Original ResearchConceptsMethicillin-Resistant Staphylococcus aureus IsolatesMethicillin-resistant Staphylococcus aureus (MRSA) detectionStaphylococcus aureus isolatesMRSA infectionRepeated infectionsInvasive diseaseLate infectionAureus isolatesInfectionSame strainInitial detectionMost casesStaphylococcus aureus detectionIsolatesPatientsDiseaseWeeks