2017
Contemporary risk model for inhospital major bleeding for patients with acute myocardial infarction: The acute coronary treatment and intervention outcomes network (ACTION) registry®–Get With The Guidelines (GWTG)®
Desai NR, Kennedy KF, Cohen DJ, Connolly T, Diercks DB, Moscucci M, Ramee S, Spertus J, Wang TY, McNamara RL. Contemporary risk model for inhospital major bleeding for patients with acute myocardial infarction: The acute coronary treatment and intervention outcomes network (ACTION) registry®–Get With The Guidelines (GWTG)®. American Heart Journal 2017, 194: 16-24. PMID: 29223432, DOI: 10.1016/j.ahj.2017.08.004.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionIntervention Outcomes Network RegistryAcute Coronary TreatmentInhospital major bleedingMajor bleedingRisk scoreCoronary TreatmentValidation cohortMyocardial infarctionHigh riskLower riskContemporary risk modelsProspective risk stratificationSimplified risk scoreHospital quality assessmentRisk adjustment methodsBaseline hemoglobinCardiogenic shockCreatinine clearanceFrequent complicationDerivation cohortHeart failureRisk stratificationSignificant morbidityCardiac arrest
2015
Development of a Hospital Outcome Measure Intended for Use With Electronic Health Records
McNamara RL, Wang Y, Partovian C, Montague J, Mody P, Eddy E, Krumholz HM, Bernheim SM. Development of a Hospital Outcome Measure Intended for Use With Electronic Health Records. Medical Care 2015, 53: 818-826. PMID: 26225445, DOI: 10.1097/mlr.0000000000000402.Peer-Reviewed Original ResearchConceptsElectronic health recordsOutcome measuresClinical dataMortality rateClinical practiceFuture quality improvement measuresRisk-standardized mortality ratesHospital risk-standardized mortality ratesLow-mortality hospitalsHealth recordsSystolic blood pressureOdds of mortalityClinical registry dataAcute myocardial infarctionHigh-mortality hospitalsHospital outcome measuresEHR dataFinal risk modelCurrent clinical practiceStandard clinical practiceFirst outcome measureNational Quality ForumCurrent electronic health recordsQuality improvement measuresChart abstraction
2014
International comparisons of the management of patients with non-ST segment elevation acute myocardial infarction in the United Kingdom, Sweden, and the United States: The MINAP/NICOR, SWEDEHEART/RIKS-HIA, and ACTION Registry-GWTG/NCDR registries
McNamara RL, Chung SC, Jernberg T, Holmes D, Roe M, Timmis A, James S, Deanfield J, Fonarow GC, Peterson ED, Jeppsson A, Hemingway H. International comparisons of the management of patients with non-ST segment elevation acute myocardial infarction in the United Kingdom, Sweden, and the United States: The MINAP/NICOR, SWEDEHEART/RIKS-HIA, and ACTION Registry-GWTG/NCDR registries. International Journal Of Cardiology 2014, 175: 240-247. PMID: 24882696, PMCID: PMC4112832, DOI: 10.1016/j.ijcard.2014.04.270.Peer-Reviewed Original ResearchConceptsNon-ST segment elevation myocardial infarctionPercutaneous coronary interventionManagement of patientsMyocardial infarctionRIKS-HIAAcute non-ST segment elevation myocardial infarctionNon-ST segment elevation acute myocardial infarctionEnzyme inhibitors/angiotensin receptor blockersSegment elevation acute myocardial infarctionElevation acute myocardial infarctionSegment elevation myocardial infarctionFuture comparative effectiveness researchAngiotensin receptor blockersPrior heart failureDual antiplatelet agentsElevation myocardial infarctionAcute myocardial infarctionComparative effectiveness researchCoronary interventionDischarge medicationsOngoing registryReceptor blockersHeart failureAntiplatelet agentsClinical registry
2007
Impact of Delay in Door-to-Needle Time on Mortality in Patients With ST-Segment Elevation Myocardial Infarction
McNamara RL, Herrin J, Wang Y, Curtis JP, Bradley EH, Magid DJ, Rathore SS, Nallamothu BK, Peterson ED, Blaney ME, Frederick P, Krumholz HM. Impact of Delay in Door-to-Needle Time on Mortality in Patients With ST-Segment Elevation Myocardial Infarction. The American Journal Of Cardiology 2007, 100: 1227-1232. PMID: 17920362, PMCID: PMC2715362, DOI: 10.1016/j.amjcard.2007.05.043.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overArrhythmias, CardiacCaliforniaCohort StudiesEmergency Service, HospitalEmergency TreatmentFemaleFibrinolytic AgentsHospital MortalityHumansMaleMedical RecordsMyocardial InfarctionOutcome Assessment, Health CareRegistriesRetrospective StudiesThrombolytic TherapyTime and Motion StudiesTime FactorsConceptsST-segment elevation myocardial infarctionElevation myocardial infarctionNeedle timeFibrinolytic therapyMyocardial infarctionHospital mortalitySymptom onsetOdds ratioReperfusion strategyAdjunctive medicationsHospital arrivalShorter doorTimely administrationNational registryRepresentative cohortPatientsMortalityInfarctionTherapyIndependent effectsCohortMinutesSmaller centersOnsetImpact of delay
2006
Strategies for Reducing the Door-to-Balloon Time in Acute Myocardial Infarction
Bradley EH, Herrin J, Wang Y, Barton BA, Webster TR, Mattera JA, Roumanis SA, Curtis JP, Nallamothu BK, Magid DJ, McNamara RL, Parkosewich J, Loeb JM, Krumholz HM. Strategies for Reducing the Door-to-Balloon Time in Acute Myocardial Infarction. New England Journal Of Medicine 2006, 355: 2308-2320. PMID: 17101617, DOI: 10.1056/nejmsa063117.Peer-Reviewed Original ResearchConceptsST-segment elevationBalloon timeCatheterization laboratoryMyocardial infarctionFaster doorEmergency departmentPrimary percutaneous coronary interventionHospital strategiesIntracoronary balloon inflationPercutaneous coronary interventionAcute myocardial infarctionMinority of hospitalsEmergency medicine physiciansReperfusion treatmentCoronary interventionBalloon inflationMedicine physiciansMultivariate analysisHospitalInfarctionPatientsMedicaid ServicesSignificant reductionReal-time data feedbackData feedback
2005
Hospital Improvement in Time to Reperfusion in Patients With Acute Myocardial Infarction, 1999 to 2002
McNamara RL, Herrin J, Bradley EH, Portnay EL, Curtis JP, Wang Y, Magid DJ, Blaney M, Krumholz HM, Investigators N. Hospital Improvement in Time to Reperfusion in Patients With Acute Myocardial Infarction, 1999 to 2002. Journal Of The American College Of Cardiology 2005, 47: 45-51. PMID: 16386663, PMCID: PMC1475926, DOI: 10.1016/j.jacc.2005.04.071.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionBalloon timeMin/yearNeedle timeMyocardial infarctionHospital characteristicsAcute ST-segment elevation myocardial infarctionPercutaneous coronary intervention cohortPercutaneous coronary intervention volumeElevation myocardial infarctionPercutaneous coronary interventionRetrospective observational studyFour-year study periodRapid reperfusionCoronary interventionFibrinolytic therapyHospital arrivalTherapy cohortReperfusion timeIntervention cohortNational registryIntervention volumeObservational studyHospital improvementPatients