1984
Time-intensity profiles of cutaneous pain in normal and hyperalgesic skin: a comparison with C-fiber nociceptor activities in monkey and human
LaMotte R, Torebjörk H, Robinson C, Thalhammer J. Time-intensity profiles of cutaneous pain in normal and hyperalgesic skin: a comparison with C-fiber nociceptor activities in monkey and human. Journal Of Neurophysiology 1984, 51: 1434-1450. PMID: 6737035, DOI: 10.1152/jn.1984.51.6.1434.Peer-Reviewed Original ResearchConceptsNociceptive afferent fibersDevelopment of hyperalgesiaConditioning stimulusPain ratingsHeat stimulationAfferent fibersHairy skinHeat-evoked dischargesCervical spinal cordMagnitude of painMild heat injurySimilar response magnitudesMean frequencyPoststimulus time histogramsNociceptor activityCutaneous painResponse latencyHyperalgesic skinSpinal cordAwake humansC-fibersAnesthetized monkeysConduction velocityPainHeat stimuliPeripheral neural correlates of magnitude of cutaneous pain and hyperalgesia: simultaneous recordings in humans of sensory judgments of pain and evoked responses in nociceptors with C-fibers
Torebjörk H, LaMotte R, Robinson C. Peripheral neural correlates of magnitude of cutaneous pain and hyperalgesia: simultaneous recordings in humans of sensory judgments of pain and evoked responses in nociceptors with C-fibers. Journal Of Neurophysiology 1984, 51: 325-339. PMID: 6707724, DOI: 10.1152/jn.1984.51.2.325.Peer-Reviewed Original ResearchConceptsConditioning stimulusIntensity-response functionsNormal skinMost subjectsC-mechanoheat nociceptorsPeripheral neural correlateHeat pain sensationMild heat injuryMagnitude ratingsReceptive fieldsHeat injurySupra-threshold stimuliShort-duration stimuliPain thresholdCutaneous painHeat painPain sensationC-fibersPainNociceptorsHairy skinUninjured skinHeat stimulationMagnitude of responseNeuronal correlates
1982
Peripheral neural mechanisms of cutaneous hyperalgesia following mild injury by heat
LaMotte R, Thalhammer J, Torebjörk H, Robinson C. Peripheral neural mechanisms of cutaneous hyperalgesia following mild injury by heat. Journal Of Neuroscience 1982, 2: 765-781. PMID: 7086482, PMCID: PMC6564351, DOI: 10.1523/jneurosci.02-06-00765.1982.Peer-Reviewed Original ResearchConceptsConditioning stimulusCutaneous hyperalgesiaMild injuryDevelopment of hyperalgesiaHeat injuryMagnitude of hyperalgesiaMild heat injurySingle conditioning stimulusMagnitude of sensitizationPeripheral neural mechanismsReceptive fieldsPeroneal nervePeripheral determinantsCutaneous receptorsC-fibersAwake humansConduction blockAnesthetized monkeysHyperalgesiaNociceptorsPainGlabrous skinNormal skinInjuryHeat stimulation